<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11861

Description kelch-like protein 12
SequenceMGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVCIWLALKAFFFLCQDSHLSPCYPHLASRAKLRFFKQLRELREVLTLRWWTSCSHSFKACFASLVSQDYVNETDQEEIRTGVDQCIQKFLDIARQTECFFLQKRLQLSVQKPEQVIKEDVSELKNKLQQKDTLVQKHLTKVQHWQQVLEDINLQHKKPADIPQGSLAYLEQPFIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNICTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK
Length689
PositionHead
OrganismDipodomys ordii (Ord's kangaroo rat)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Castorimorpha> Heteromyidae> Dipodomyinae> Dipodomys.
Aromaticity0.08
Grand average of hydropathy-0.201
Instability index47.18
Isoelectric point5.86
Molecular weight77532.74
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11861
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     455.75|      45|      45|     596|     640|       1
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  406-  449 (56.76/34.48)	..VVGGF.GSqqSPIDVVEKYDPKTQE...WSFLPSITRKRRYVASVSLH
  452-  499 (73.06/46.58)	IYVIGGYDGR..SRLSSVECLDYTADEdgvWYSVAPMNVRRGLAGATTLG
  502-  546 (78.13/50.33)	IYVSGGFDGS..RRHTSMERYDPNIDQ...WSMLGDMQTAREGAGLVVAS
  549-  593 (81.36/52.73)	IYCLGGYDGL..NILNSVEKYDPHTGH...WTNVTPMATKRSGAGVALLN
  596-  640 (85.14/55.54)	IYVVGGFDGT..AHLSSVEAYNICTDS...WTTVTSMTTPRCYVGATVLR
  643-  687 (81.30/52.69)	LYAIAGYDGN..SLLSSIECYDPIIDS...WEVVTSMGTQRCDAGVCVLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.80|      22|      43|     147|     189|       2
---------------------------------------------------------------------------
  147-  168 (39.70/55.05)	CVDLMQAAEVF..SQKHFPEVVQH
  191-  214 (39.11/14.29)	CIWLALKAFFFlcQDSHLSPCYPH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     163.63|      40|      45|     240|     279|       3
---------------------------------------------------------------------------
  240-  279 (67.99/46.33)	TSCSH............................SFKACFASLVSQDYVNETDQEEIRTGVDQ...CIQKFL
  285-  327 (56.61/37.34)	TECFF............................LQKRLQLSVQKPEQVIKEDVSELKNKLQQkdtLVQKHL
  328-  390 (39.03/23.45)	TKVQHwqqvledinlqhkkpadipqgslayleqPFIRC..SLQCRDLVDEAKKFHLRPELRS...QMQ...
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11861 with Med28 domain of Kingdom Metazoa
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