<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11843

Description mediator of RNA polymerase II transcription subunit 15a-like
SequenceMDSNNWRPNPGTEPTIDTSEWRAQLQPDSRQRIVNKIMDTSKKHLPVSGSEGLLELWKIAQRFEEKIFTAATSQSDYLRKISMKMLTMETKSQSSIANNMPSNEGGPSNKPPDQDNSHLMDSNNWRPNPGTEPTIDTSEWRAQLQPDSRQRIVNKIMDTLKKHLPVSGSEGLLELWKIAQRFEEKIFTAATSQSDYLRKISMKMLTMETKSQSSIANNMPSNEGGPSNKPPDQDNSHLMDSNNWRPNPGTEPTIDTSEWRAQLQPDSRQRIVNKIMDTLKKHLPVSGSEGLLELWKIAQRFEEKIFTAATSQSDYLRKISMKMLTMETKSQSSIANNMPSNEGGPSNKPPDQGFVLQSQALNQGQQHPNPLPSQHQPRQQLLSQTIQNNVAPQPNLPSVSSLSQNSGQNINQNSNTQPGQNSAGNTIGHNSNVQSMFSGSQRQMPGRQQVVPQQQQQSQNQQHILYPQQLLKQKFQMSQMQQQQQQQNLLQPNQLQSSQQSVMQPSMLQSSLSSLPQNQQSNNVQQSTQSRLQQHSQIIRQQQLQQQNSIAHQQQTPMAQQQQQQQLVGTQSNATNGPHAQLLGQQNNVGDTQKSQRLLSQQNNLMNLQQRQQLMNQQNNLTNIHQQQLGNNVPGSQQQQQLFGTESGNQGIQTSHHSAHMLQQSKVSMQQQLQQNASKLLPSHLQQSQPQASQQQLMSQIHNQPTQMQQQLGLQQQPNTLQRDMQQKLQASGSLLQQQSVLDQQKQLYQSQRALPETSTTSVDSTTQTGQPSGVDWQEEVYQKMQTMKENYLPDMNEMCQKISLRLQQHDSNPQQPKSDQIEKLRAYKMMLERMIAILQIPKNSILPSFREKLGSYEKQIVNLINSIRPRRSGSSLQPGQLPPTHVPSMQQSQSQTHQMPQVNQMSDINDMKMRQGMSVKPGVFQPHLTSDGAYGNALAATSGKSTAEQPLERLVRAVQSMSTKTLSAAVNDISSVVSMTDRIAGSAPGNGSRAAVGEDLVSITNCRLQARNFTTQDGSNGTKKIKRYISSRPLKNVSSAGSMNDSINQFSASEASQQKSTASSNFTKPKAEVSHALLEEIRQINCRLIDTVVDICDEDVDPTIASVTAAEGAEGTIVKCSFIPVALSPSLKCHYASLQSPIQPLRLLVPQNYPNCSPIFLDKLPVESCKGNADLTEKAKLKFSVALRSVSQPFSVKDIAKTWDSSARGAVSDYAQQFGGGTFSSKYGTWEDCLAA
Length1237
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.04
Grand average of hydropathy-0.851
Instability index65.74
Isoelectric point9.22
Molecular weight137905.69
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11843
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|    1075.01|     116|     116|      56|     171|       1
---------------------------------------------------------------------------
    1-   52 (77.90/22.71)	...................................................................................MDSNN.WRPNP..GTE...PT.IDTSEWRAQL.QPDSR...........QRIVNKIMDTSKKHLPVSGSEG
   56-  171 (246.95/89.02)	LWKIAQR.FEEKIFTA..ATSQS......DYLRKISMKMLTMETKSQSSIANNMPSNEGGPSNKPPDQD........NSHL..MDSNN.WRPNP..GTE...PT.IDTSEWRAQL.QPDSR...........QRIVNKIMDTLKKHLPVSGSEG
  175-  290 (246.95/89.02)	LWKIAQR.FEEKIFTA..ATSQS......DYLRKISMKMLTMETKSQSSIANNMPSNEGGPSNKPPDQD........NSHL..MDSNN.WRPNP..GTE...PT.IDTSEWRAQL.QPDSR...........QRIVNKIMDTLKKHLPVSGSEG
  294-  397 (188.52/66.10)	LWKIAQR.FEEKIFTA..ATSQS......DYLRKISMKMLTMETKSQSSIANNMPSNEGGPSNKPPDQG.....fvlQSQA..LNQGQ.QHPNP....L...PS...QHQPRQQL.LS..............QTIQNNVAP..QPNLP......
  398-  478 (74.11/21.22)	.............................................SVSSLSQNSGQNINQNSNTQPGQNsagntighNSNVqsMFSGS.QRQMP..GRQ...QV.VP....QQQQ.QSQNQ...........QHILYP.QQLLKQKFQMS....
  507-  604 (82.47/24.50)	.........................................MLQSSLSSLPQNQQSNNVQQSTQSRLQQ........HSQI..IRQQQlQQQNSiaHQQ...QTpMAQQQQQQQLvGTQSNatngphaqllgQ..QNNVGDTQKSQRLLSQQNN
  608-  688 (94.04/29.04)	L...QQR...QQLM......NQQ......NNLTNIH..........QQQLGNNVP....GSQQQQ..Q...............LF...........GTEsgnQG.IQTSHHSAHM.LQQSK.......vsmqQQLQQNASKLLPSHLQQS....
  748-  821 (64.08/17.29)	LYQ.SQRaLPETSTTSvdSTTQTgqpsgvDWQEEVYQKMQTMKENYLPDM......NEMCQKISLRLQQ..........H....DSNP.QQPKS..DQ........................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     128.68|      26|      26|     689|     714|       2
---------------------------------------------------------------------------
  479-  503 (39.54/13.47)	QMQ..QQQQQQNL.LQPNQLQssQQSVM
  689-  714 (47.97/18.22)	QPQASQQQLMSQIHNQPTQMQ..QQLGL
  717-  742 (41.17/14.39)	QPNTLQRDMQQKLQASGSLLQ..QQSVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.81|      27|      61|     968|     994|       3
---------------------------------------------------------------------------
  968-  994 (44.72/32.55)	SAAVNDISSVVSMTDRIAGSAPGNGSR
 1032- 1058 (45.09/32.90)	SRPLKNVSSAGSMNDSINQFSASEASQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.76|      14|      16|     870|     883|       4
---------------------------------------------------------------------------
  870-  883 (26.68/12.13)	PRRSGSSLQPGQLP
  888-  901 (23.96/10.01)	PSMQQSQSQTHQMP
  913-  926 (23.12/ 9.37)	KMRQGMSVKPGVFQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11843 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FQMSQMQQQQQQQNLLQPNQLQSSQQSVMQPSMLQSSLSSLPQNQQSNNVQQSTQSRLQ
2) HSQIIRQQQLQQQNSIAHQQQTPMAQQQQQQQLVGTQSNATNGPHAQLLGQQNNVGDTQKSQRLLSQQNNLMNLQQRQQLMNQQNNLTNIHQQQLGNNVPGSQQQQQLFGTESGNQGIQTSHHSAHMLQQSKVSMQQQLQQNASKLLPSHLQQSQPQASQQQLMSQIHNQPTQMQQQLGLQQQPNTLQRDMQQKLQASGSLL
3) IRPRRSGSSLQPGQLPPTHVPSMQQSQSQTHQMPQVNQMSDINDMKMRQGMSVKPGVFQP
4) KQLYQSQRALPETSTTSVDSTTQTGQPSGVDWQEEV
5) LRKISMKMLTMETKSQSSIANNMPSNEGGPSNKPPDQGFVLQSQALNQGQQHPNPLPSQHQPRQQLLSQTIQNNVAPQPNLPSVSSLSQNSGQNINQNSNTQPGQNSAGNTIGHNSNVQSMFSGSQRQMPGRQQVVPQQQQQSQNQQHILYPQQLLKQ
6) MDSNNWRPNPGTEPTIDTSEWRAQLQPDSRQRIVNKIMDTSKKHL
7) METKSQSSIANNMPSNEGGPSNKPPDQDNSHLMDSNNWRPNPGTEPTIDTSEWRAQLQPDSRQRIVNKIMDTLK
8) METKSQSSIANNMPSNEGGPSNKPPDQDNSHLMDSNNWRPNPGTEPTIDTSEWRAQLQPDSRQRIVNKIMDTLK
9) QTMKENYLPDMNEMCQKISLRLQQHDSNPQQPKSDQIEKLR
475
535
868
746
316
1
88
207
786
533
736
927
781
473
45
161
280
826










Molecular Recognition Features






MoRF SequenceStartStop




1) KKIKRYIS
1024
1031