<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11842

Description mediator of RNA polymerase II transcription subunit 16-like isoform X1
SequenceMNQISVTKDSEQGEPVAQSILPQPQQNLPNVSDNTDSVSAQEQEVVAEDKSPPMEQPMDEDSVIPATVFTIMLKQSKSDLQHKMSVPELCRNFSAVSWCGKLNAIACAAETCARIPSSTANPPFWIPIHIVIPERPTECAVFNVIADSPRDSVQFIEWSPTSCPRALLIANFHGRVTIWTQPSQGPANLVRDASCWQHEHEWRQDIAVATKWLSGVSPYRWLSSKSSAPTNPKVTFEEKFLSQQSQTSARWPNFLCVCSVFSSGSVQLHWSQWPPSQNGSTPSWFHTSKGLLGCGPSGIMAGDAIITDSGAMHVAGVPIVNPSTIVVWEVTPGPGNSFQATPKTSTASGVPPLISPNWAGFAPLAGYLFCWQDYLLSQAKQGKKLTDKNLGDAVPLYCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRAGSVIAVVIVEGQYMSPSDPDEGPSITGWRVQRWESSLQQVVLHPIFGNPTSSMGGQPPMQTVWQSKVDLSIPPTNDFKCHQSPAIGMSTDVQKLSEPVPDKSKRVNFDPFDLPSDIRTLARIVYSAHGGEIAIAFLRGGVHIFSGPNFAPVDNYQVTVGSSIAAPAFSSTSCCSASVWHDTGKNCTILKIIRVLPPPTPISQVKANSSTWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSVQHRQQYGPSLDRIKCRLLEGSNAQEVRAMVLDMQARLLLDMLGRGIESAFINSSALVPELWQASGETLSSIDPETMAVEPALIPCVQAYVDAILDLASHFITRLRRYASFCRTLASHAVTAGTGSNRNLVASPTQSSATPATSQGGQNGSASSMGSTQLQTWVQGAIAKISNTTDGGSNPTPNPISGPSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLPRYMGAANRTTDTNIQKSNAPASGKVEEISKPVSAVAKSEDGLTGRAGQLMSGSKGSEEAPSGRSRLGSGNAGQGYTFEEVKVLFMMLMELCRRTAGLQHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDPEDVDFANDQSKVVFSDPRDLSSVEHCDAYYGTHRLWPRKRRMSERDAAFGLNTSVGLGAYLGIMGSRRDVVTATWKTGLEGVWYKCIRCQRQTSAFASSGSTASPSQNEREMWWISRWAYGCPMCGGTWVRVV
Length1245
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.08
Grand average of hydropathy-0.200
Instability index48.13
Isoelectric point6.25
Molecular weight134962.04
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11842
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     591.18|     130|     136|     328|     461|       1
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  158-  281 (194.38/78.22)	WSPTSCPRALLIAN..F....HGRVTIWTQPSQGP.....ANLVRDASCWQHE..HEWRQDIAVAT.KWLSGVSP.YRWLSSKSSAPTNPKVtfeekflSQQSQTSARWPN..FLCVCSV..FSSGSV......QLHW.SQWPPSQ...NGST
  328-  461 (215.82/95.09)	WEVTPGPGNSFQAT..P....KTSTASGVPPLISPNWAGFAPLAGYLFCWQDYLLSQAKQGKKLTD.KNLGDAVPLYCSPVSNFSAYVSPEA.......AAQSAATTTWGS..GVTAVAFdpTRAGSViaVVIVEGQYMSPSDPDE...GPSI
  464-  598 (180.97/72.39)	WRVQRWESSLQQVVlhPifgnPTSSMGGQPPM.QTVWQSKVDLS..IPPTNDFKCHQSPAIGMSTDvQKLSEPVPDKSKRV.NFDPFDLP.S.......DIRTLARIVYSAhgGEIAIAF..LRGG....VHIFSGPNFAPVDNYQvtvGSSI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     165.16|      47|     569|     614|     670|       2
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  614-  670 (74.25/63.73)	WHdTGKNCTILKIIRVlppPTPISQVKANSSTWERAIAER.FWWsllvgVDWWdAVGC
 1187- 1234 (90.91/49.56)	WK.TGLEGVWYKCIRC...QRQTSAFASSGSTASPSQNEReMWW.....ISRW.AYGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.37|      35|      72|     856|     894|       3
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  856-  894 (56.25/40.66)	TQLQTWVqGAIAKisnTTDGGSNPTPNPISGPSTFM..PIS
  931-  967 (57.12/30.30)	TQLPRYM.GAANR...TTDTNIQKSNAPASGKVEEIskPVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     234.08|      70|      74|    1011|    1083|       4
---------------------------------------------------------------------------
 1011- 1083 (111.84/76.20)	FEEVKvLFMMLMELCRRTA.GLQHPLPvSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHmQNMPRPRGA...DAA
 1087- 1160 (122.24/71.01)	LRELE.LHPPAEEWHRRNMfGGPWSDP.EDVDFANDQSKVVFSDPRDLSSVEHCDAYYGTH.RLWPRKRRMserDAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.82|      25|     114|     783|     810|       6
---------------------------------------------------------------------------
  783-  810 (38.55/46.25)	PCVQAyVDAILDlaSHFITRLRRYASFC
  901-  925 (50.27/43.02)	PGTPA.VRLIGD..CHFLHRLCQLLLFC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11842 with Med16 domain of Kingdom Viridiplantae
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