<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11828

Description mediator of RNA polymerase II transcription subunit 16-like isoform X4
SequenceMVPCLLSPCIIDIKFPWEGNYLDSTISTRWPNFLCVCSVFSSGSVQLHWSQWPPSQNATPPKWFYTSKGLLGCGPSGIMAGDAIITESGAMHVAGVPIVNPSTIVVWEVMPGPGNGFQLTPKISINNGVPPLSPPNWSGFAPLAAYLFSWQDYLLSAEKQGRNQTDQNLGESIPLHCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTCGGSVIAVVIVEGQYMSPSDPDEGPSITGWRVQRWESSFQHVVLHPIFGNPTSSMGGKPPMQTIWQSKVDMSIPPTNDFKSRQTPPIGMSANVQKASESGADKSKGVNFDPFDLPSDIRTLARVVYSAHGGEIAIAFLRGGVHIFSGLNFAPVANYQINVGSAIAAPAFSSTSCCSASVWHDASKDHTILKIIRVLPPAIPIGQVKANSSIWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAILDADFHSLPTAQHRQQYCPSLDRIKCRLLEGSNAQEVRAMVLDMQARLLLDMLGKGIESALINPSALVPDPWQVSGETLSNIDPEAVSVEPALIPCIQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGTGSNRSMVASPSQNSTTPATSQGGENGTTSSSGNTQMKAWVQGAIAKISSTSDGVSNLTPNPPISGPSSLMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRSQLPRYMSSAQRTADTNSQKPHPNASVPCKMEEVAKPVSSGVRSDDSQTGRVGQPVNGSKGGEEPSPGRSRLGTGNAGQGYTFEEVKVLFLVLMDLCRRTSGLQHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNTFGGPWTDPNDEDCANDSPKLVSLNPLDSSSLENSDVYYAANGLWPRKRRLSERDAAFGLNTSVGLGAYLGIMGSRRDVVTTLWKTGLEGVWYKCIRCLRQTCAFASPGSTNLPNQNDREIWWVSRWAYGCPMCGGRWARVV
Length1027
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.08
Grand average of hydropathy-0.148
Instability index44.53
Isoelectric point6.50
Molecular weight110836.33
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11828
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     522.16|     108|     137|      37|     172|       1
---------------------------------------------------------------------------
   37-  146 (198.29/97.06)	CSVFSSGSVQLhwSQWPPSQNATPPKWFYTSKGLLG......CGPSG.........IMAGDAIITESGAMHVAGV.......PIVNPSTIVVWEVMPGPGNGFQ...LTP....KISINNGVPPLSPPNWSGFAPLAAY
  177-  285 (143.16/92.67)	CSPVSNFSAYV..SPEAAAQSAATTTW...GSGVTAvafdptCGGSV.........IAV...VIVE.GQYMSPSD.......PDEGPS.ITGWRVQRWE.SSFQhvvLHPifgnPTSSMGGKPPMQ.TIWQSKVDMS..
  287-  369 (111.26/46.05)	.......................PPTNDFKSR...Q......TPPIG.........MSANVQKASESGADKSKGV....nfdPFDLPSDIRTLARVVYSAHGGE...IAI....AF.LRGGVHIFSGLN...FAPVANY
  611-  684 (69.44/23.56)	.................PSQNSTTPA...TSQG..........GENGttsssgntqMKAWVQGAIAKISSTSDGVsnltpnpPISGPSS..................LMP.....ISINTGTFPGTP............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.90|      13|     113|     577|     589|       2
---------------------------------------------------------------------------
  577-  589 (26.05/19.14)	HFITRLRRYASFC
  693-  705 (26.85/19.96)	HFLHRLCQLLLFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.43|      23|     533|     427|     454|       3
---------------------------------------------------------------------------
  427-  449 (46.57/20.16)	RAIAER....FWWSLLVGVDWWDAVGC
  962-  983 (40.82/16.30)	RDVVTT....LWKTGLEGV.WYKCIRC
  996- 1016 (30.03/15.35)	TNLPNQndreIWW.....VSRW.AYGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     284.79|      78|     286|     486|     565|       4
---------------------------------------------------------------------------
  486-  565 (129.54/74.16)	PSLDRikCRLLEGSNAQ.....EVRAMVLDMQAR...LLLDMLGK..GIESALINPSALV.PDPW.QVSGETLS...NIDPEAVSVEPALIPCIQ
  775-  854 (94.31/48.60)	PSPGR..SRLGTGNAGQgytfeEVKVLFL........VLMDLCRRtsGLQHPL..PVSQVgSSNI.QVRLHYIDgnyTVLPEV..VEASLGPHMQ
  856-  911 (60.94/28.40)	..........................MPRPRGADaagLLLRELEL..HPPAEEWHRRNTF.GGPWtDPNDEDCA...NDSPKLVSLNP.......
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11828 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GTGSNRSMVASPSQNSTTPATSQGGENGTTSSSGNTQ
2) MSSAQRTADTNSQKPHPNASVPCKMEEVAKPVSSGVRSDDSQTGRVGQPVNGSKGGEEPSPGRSRLGTGNA
600
717
636
787










Molecular Recognition Features






MoRF SequenceStartStop




NANANA