<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11827

Description mediator of RNA polymerase II transcription subunit 16-like isoform X1
SequenceMNQIKEDFDGEELSFSNSNSKNEATVTVSVPKEEDEAEEEEEEEEDPMEYPMEVDEQDSVSLSPATVFRIRLRQPTSNLLHKMPLPEICRNFSAVSWCGKLNAIACASETCARIPRSTVNPPFWIPIHIVIPERPTESAVFNVIADSPRDSVQFIEWSPACCPRALLISNFHGRVTIWTQPSQGPANLVVDSSCWLQEHEWRQDIAVATKWLSGVSLYRWLSSKSSAPSNSKSIFEEKFISQQSQTSARWPNFLCVCSVFSSGSVQLHWSQWPPSQNATPPKWFYTSKGLLGCGPSGIMAGDAIITESGAMHVAGVPIVNPSTIVVWEVMPGPGNGFQLTPKISINNGVPPLSPPNWSGFAPLAAYLFSWQDYLLSAEKQGRNQTDQNLGESIPLHCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTCGGSVIAVVIVEGQYMSPSDPDEGPSITGWRVQRWESSFQHVVLHPIFGNPTSSMGGKPPMQTIWQSKVDMSIPPTNDFKSRQTPPIGMSANVQKASESGADKSKGVNFDPFDLPSDIRTLARVVYSAHGGEIAIAFLRGGVHIFSGLNFAPVANYQINVGSAIAAPAFSSTSCCSASVWHDASKDHTILKIIRVLPPAIPIGQVKANSSIWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAILDADFHSLPTAQHRQQYCPSLDRIKCRLLEGSNAQEVRAMVLDMQARLLLDMLGKGIESALINPSALVPDPWQVSGETLSNIDPEAVSVEPALIPCIQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGTGSNRSMVASPSQNSTTPATSQGGENGTTSSSGNTQMKAWVQGAIAKISSTSDGVSNLTPNPPISGPSSLMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRSQLPRYMSSAQRTADTNSQKPHPNASVPCKMEEVAKPVSSGVRSDDSQTGRVGQPVNGSKGGEEPSPGRSRLGTGNAGQGYTFEEVKVLFLVLMDLCRRTSGLQHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNTFGGPWTDPNDEDCANDSPKLVSLNPLDSSSLENSDVYYAANGLWPRKRRLSERDAAFGLNTSVGLGAYLGIMGSRRDVVTTLWKTGLEGVWYKCIRCLRQTCAFASPGSTNLPNQNDREIWWVSRWAYGCPMCGGRWARVV
Length1247
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.08
Grand average of hydropathy-0.220
Instability index50.20
Isoelectric point5.78
Molecular weight135628.57
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11827
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     519.95|     108|     137|     257|     392|       1
---------------------------------------------------------------------------
  257-  366 (200.57/81.44)	CSVFSSGSVQLhwSQWPPSQNATPPKWFYTSKGLLG......CGPSGIMAGD...........AII....TESG.AMHVAGV...PIVNPSTIVVWEVMPGPGNGFQ...LTP....KISINNGVPPLSPPNWSGFAPLAAY
  397-  500 (135.24/73.23)	CSPVSNFSAYV..SPEAAAQSAATTTW...GSGVTAvafdptCGGSVIAV..............VI....VE.G.QYMSPSD...PDEGPS.ITGWRVQRWE.SSFQhvvLHPifgnPTSSMGGKPPMQ.TIWQS.......
  505-  589 (120.72/42.67)	.SI....................PPTNDFKSR...Q......TPPIGMSANV...........QKA....SESG.ADKSKGVnfdPFDLPSDIRTLARVVYSAHGGE...IAI....AF.LRGGVHIFSGLN...FAPVANY
  831-  904 (63.43/16.75)	.................PSQNSTTPA...TSQG..........GENGTTSSSgntqmkawvqgAIAkissTSDGvSNLTPNP...PISGPSS..................LMP.....ISINTGTFPGTP............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     142.61|      31|     533|     629|     674|       2
---------------------------------------------------------------------------
  639-  669 (60.02/40.64)	KANSSIWERAIAERFWWSLLVGVDWWDAVGC
 1182- 1203 (33.55/10.42)	........RDVVTTLWKTGLEGV.WYKCIRC
 1212- 1236 (49.04/27.73)	SPGSTNLPNQNDREIWW.....VSRW.AYGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.90|      13|     115|     797|     809|       3
---------------------------------------------------------------------------
  797-  809 (26.05/17.80)	HFITRLRRYASFC
  913-  925 (26.85/18.56)	HFLHRLCQLLLFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     284.79|      78|     286|     706|     785|       6
---------------------------------------------------------------------------
  706-  785 (129.54/69.27)	PSLDRikCRLLEGSNAQ.....EVRAMVLDMQAR...LLLDMLGK..GIESALINPSALV.PDPW.QVSGETLS...NIDPEAVSVEPALIPCIQ
  995- 1074 (94.31/45.32)	PSPGR..SRLGTGNAGQgytfeEVKVLFL........VLMDLCRRtsGLQHPL..PVSQVgSSNI.QVRLHYIDgnyTVLPEV..VEASLGPHMQ
 1076- 1131 (60.94/26.40)	..........................MPRPRGADaagLLLRELEL..HPPAEEWHRRNTF.GGPWtDPNDEDCA...NDSPKLVSLNP.......
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11827 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GTGSNRSMVASPSQNSTTPATSQGGENGTTSSSGNTQ
2) MNQIKEDFDGEELSFSNSNSKNEATVTVSVPKEEDEAEEEEEEEEDPMEYPMEVDEQ
3) MSSAQRTADTNSQKPHPNASVPCKMEEVAKPVSSGVRSDDSQTGRVGQPVNGSKGGEEPSPGRSRLGTGNA
820
1
937
856
57
1007










Molecular Recognition Features






MoRF SequenceStartStop




1) MNQIKEDFDGEELSF
1
15