Description | Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MISGLQEIDKLKSQVQDIHVPLEVFDYIDQGRNPQLYTKDCIEKALTKNEQVKGKIDAYRKFKAHMLVELSGAFPNELAKYRAIRGGDETPPSY |
Length | 94 |
Position | Middle |
Organism | Diaphorina citri (Asian citrus psyllid) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Paraneoptera> Hemiptera> Sternorrhyncha> Psylloidea> Liviidae> Diaphorina. |
Aromaticity | 0.09 |
Grand average of hydropathy | -0.614 |
Instability index | 27.33 |
Isoelectric point | 6.72 |
Molecular weight | 10741.17 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP11823 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) QLYTKDCIEKALTKNEQVKGKIDAYRKFKAHMLVELSGAFPNELAKYRAIRGGDETPPSY 2) QVQDIHVPLEVFDYIDQGR | 35 14 | 94 32 |
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