<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11813

Description mediator of RNA polymerase II transcription subunit 26
SequenceFQTTRLGKYINELRRKTKNELLAKRAKDLVRRWRDMILPTQASDSSVNGKTVSQPTSPDPPVEAVPRTHAANKRLRKEDSPDSKSEEPVTKIARLNGSTVRPIFTPETSRDGFNSKSDNELVPQEIINIDDEPEVPTGPKKRGRKKGSKNKSTLAKAAAALAQKSTEDIVQDKIVALARTPKVKTTQELLADLRSRSGEEIPLVKLPQSIENKASLANCVLTKLEPHEDEDDGVDIKSDHKSLTKQECDNNSNNVNVVVIDKEKKSKKHKHSDTNRSEAAQSMKSSPPPPPVPPEPSSVEEILSRLPPLNLDAIDWSEDSYSVPNSPRPVCEEDVEQLHTEHCEGLNGNWEKRDDQKTEFREWHEMLTIRSSSNESEPPLFVLPYAVVD
Length387
PositionUnknown
OrganismDiaphorina citri (Asian citrus psyllid)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Paraneoptera> Hemiptera> Sternorrhyncha> Psylloidea> Liviidae> Diaphorina.
Aromaticity0.03
Grand average of hydropathy-0.949
Instability index68.61
Isoelectric point6.17
Molecular weight43526.21
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11813
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     178.77|      55|     121|     111|     231|       2
---------------------------------------------------------------------------
  107-  161 (90.85/56.25)	ETSRDGFNSKSDNE.LVPQEIINIDDEPEVPTGPKKRGRKKGSKNKSTLAKAAAAL
  228-  283 (87.91/84.21)	EDEDDGVDIKSDHKsLTKQECDNNSNNVNVVVIDKEKKSKKHKHSDTNRSEAAQSM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.82|       8|     227|      57|      66|       3
---------------------------------------------------------------------------
   57-   66 (13.69/ 9.83)	SPDPPveAVP
  286-  293 (20.14/ 8.67)	SPPPP..PVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.69|      20|     174|     187|     207|       4
---------------------------------------------------------------------------
  187-  207 (30.89/22.44)	QELLAdLRSRSGE.EIPLVKLP
  364-  384 (33.80/19.71)	HEMLT.IRSSSNEsEPPLFVLP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11813 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IDWSEDSYSVPNSPRPVCEEDVEQLHTEHCEGLNGNWEKRDDQKTEFREWHEMLTI
2) SLANCVLTKLEPHEDEDDGVDIKSDHKSLTKQECDNNSNNVNVVVIDKEKKSKKHKHSDTNRSEAAQSMKSSPPPPPVPPEPSSVEEILSR
3) WRDMILPTQASDSSVNGKTVSQPTSPDPPVEAVPRTHAANKRLRKEDSPDSKSEEPVTKIARLNGSTVRPIFTPETSRDGFNSKSDNELVPQEIINIDDEPEVPTGPKKRGRKKGSKNKSTLAKAAAALA
314
215
33
369
305
162










Molecular Recognition Features






MoRF SequenceStartStop




1) LLAKRAKDLVRRWRDMILPTQA
2) PLFVLPYAVVD
3) PLNLDAIDWSEDSY
4) QKTEFREWHEMLTIRS
21
379
308
356
42
389
321
371