Description | mediator of RNA polymerase II transcription subunit 21-like isoform X2 |
Sequence | MADRLTQLQDFINQQADNFCNSVGILQQTAIPSKFSGFDRGGSQTPQQQTQQEDYAHLFATLISRCARDIDALIESLPNEDSTTELQLASLRKLEQDNQGAAERLEDTVRRGELLLEQIQAALTDIAQSQLETNGVVQEKPVEPS |
Length | 145 |
Position | Middle |
Organism | Diaphorina citri (Asian citrus psyllid) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Paraneoptera> Hemiptera> Sternorrhyncha> Psylloidea> Liviidae> Diaphorina. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.577 |
Instability index | 53.77 |
Isoelectric point | 4.31 |
Molecular weight | 16103.56 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP11810 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) ERLEDT 2) FSGFDRG 3) QQTQQEDYAHLFATLISRCARDIDALIESLPNEDSTTELQLASLRKLEQDNQ | 103 35 48 | 108 41 99 |
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