<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11799

Description mediator of RNA polymerase II transcription subunit 23 isoform X1
SequenceMDQSQRSSSLTAVSTSRAYQFHPARAAIVNLFDLYLGRSNRLKHEDSAREPPNKAQKRVLAINRELPPRNEQFLLDFEQIQNQFSDHDQLRAVTESVLISLVVQCSGHVPRAEFLLFALRSLCSISYINWDTFLPSLLSSISSAEVSMGQGSQAAPTVSTTNLSQSGVLPSSNPVPNSSTFQSSNPASPLPSVHGISSPAQSSIDPSSCTALSPIKSSDLSGTGLPSAVRVNSFLRNNAISSLRQLCCKIILSGLKFDLKPVTHADIFSHMLNWMVNWDQRQQGMEESENMKSWRPDKALIEWLHSCLDVVWLLVEENKCRVPFYELLRSGLQFIDNIPDDEALFTLILEIHRRRDMMAMHMQMLDQHLHSPTFGTQRIFSQTMQNISGEAVASLRYSPITYPSVLGEPLHGEDIASAIQRGTRDWERAMRCIRHALRTTPSPDWWKRVLLVAPGYRSSAQGLSPGAVFTSEMICEATIDRIFELLKLTNSEIHCWQEWLVFSDIFFFLMKSGCIDFADFVAKLFSRVTEGGQHVLRTNHVTWLFAQIIRVELVMSALNSDARKVETTRKIISFHREDKNADPNNPQSILLDFISSCQNLRIWSLNTTTREYLNSEQLQKGKQIDEWWRQASKGDRMVDYMNMDDKSIGMFWVVSYTMAQPACETVMNWLTSAGAPELSSAQNLQTNERIMVMREVSPLPMSLLSGFSMNLCSKLAYQMEESLFSGQAVPSIALAETYTRLLLLAPHSLFRSHFNHLAQRNPSLLSRPGVTLLVLEILNYRLLPLYRYQGKSKALMYDVTKIISALKGKRGDHRVFRLAENLCMNLIFSLRDFFFVKREGKGPTEFTETLNRLAVVTLAILIKTRGIADADHLLYLQTMLEQTMATSQHTWSEKTLRYFPPVLREVLIGRIDKRGVAIQAWQQAETTVINQCNQLLSPSADPTYVMTYISHSFPQHKQYLCAGAWILMQGHPESINCTTLARVLREFSPEEVTANIYTMVDVLLHHIQIEPQHGHSTQDILLKVCANLSFFVWTQELLPLDILLLAFIDRDDDPNALRIVISLLDRQELQQRVKLYCISRGSPEHWLHSVVFKRNELQKALGNHLSWKDRYPVFFDDIAARLLPVIPLIVYRLIENDAVDQADRVLAMYSPFLAYHPLRFTFVRDILAYFYSHLPNKLIVRILYVLDISKIPFSESFPQHISSAGPVMCPPMDYFATLLLGLVNNVIPSLQTSKSGTAGDASSSSMRPSHNKAPGTNPPVATSAPESQKAFYQIQDPGTYTQLVLETAVIELLSLPVSAGQIVSSLVQIVVNIQPTLIQSSNNLHVAPSSMGQGSALPTSPSGGSTDSLNAGRSNTSVSGINTPNFVSRSGYTCQQLSSLMIQACGLLLAQLPQEFHGQLYLEASRIIKETWWLSDATRSLGELNSAVGYSLMDPTWAAQDNTSTAIGNTVALLHSLFSNLPQEWLEGAHVIIKHLRPVTSVAMLRIVFRIIGPLLPKLANAHSLFCKTLSSLLSVMVDVFGKNSQTSIPVEAAEIADLIDFLHHVVHYEGQGGPVVASSKPRQEVLAIIGRALENLRPDVQHLLSHLKPDTTSSIYAATHPKLVQNPA
Length1609
PositionTail
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.08
Grand average of hydropathy-0.062
Instability index45.63
Isoelectric point6.90
Molecular weight180205.86
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11799
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.62|      18|     123|     114|     146|       1
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  116-  133 (35.32/36.25)	LFALRSLCSISYINWDTF
 1349- 1366 (33.30/ 6.47)	LNAGRSNTSVSGINTPNF
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.78|      18|     324|     388|     406|       2
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  388-  406 (27.88/22.16)	SGEAVASLRYSPiTYPSVL
  725-  742 (30.90/19.49)	SGQAVPSIALAE.TYTRLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     135.79|      65|     324|    1086|    1162|       3
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  303-  330 (22.17/ 6.39)	...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................WLHScldVVWLLVEENK......C...RVP.FYELLRS
  333-  374 (53.49/24.67)	QFIDNIPddEALFTLILE..IHRRRDMMAMHMQMLDQHLHSPTF.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
 1086- 1120 ( 9.75/21.96)	............................................gtqrifsqtmqnisgeavaslryspitypsvlgeplhgediasaiqrgtrdweramrcirhalrttpspdwwkrvllvapgyrssaqglspgavftsemiceatidrifellkltnseihcwqewlvfsdiffflmksgcidfadfvaklfsrvteggqhvlrtnhvtwlfaqiirvelvmsalnsdarkvettrkiisfhredknadpnnpqsilldfisscqnlriwslntttreylnseqlqkgkqidewwrqaskgdrmvdymnmddksigmfwvvsytmaqpacetvmnwltsagapelssaqnlqtnerimvmrevsplpmsllsgfsmnlcsklayqmeeslfsgqavpsialaetytrllllaphslfrshfnhlaqrnpsllsrpgvtllvleilnyrllplyryqgkskalmydvtkiisalkgkrgdhrvfrlaenlcmnlifslrdfffvkregkgpteftetlnrlavvtlailiktrgiadadhllylqtmleqtmatsqhtwsektlryfppvlrevligridkrgvaiqawqqaettvinqcnqllspsadptyvmtyishsfpqhkqylcagawilmqghpesincttlarvlrefspeevtaniytmvdvllhhiqiepqhghstqdillkvcanlsffvwtqellpldilllafidrdddpnalrivislldrqelqqrvklycisrgspehWLHS...VVFKRNELQKalgnhlSwkdRYPvFFDDIAA
 1121- 1162 (50.38/28.06)	RLLPVIP..LIVYRLIENdaVDQADRVLAMYSPFLAYHPLRFTF.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.81|      18|     181|    1011|    1031|       4
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 1011- 1031 (29.91/25.66)	PQHGHSTQDILlkvCANLSFF
 1198- 1215 (37.89/24.11)	PQHISSAGPVM...CPPMDYF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.97|      22|      43|     913|     935|       6
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  913-  935 (35.11/24.24)	KRGVAIQAW..QQAETTVINqCNQL
  957-  980 (38.86/22.38)	KQYLCAGAWilMQGHPESIN.CTTL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     189.16|      71|    1180|      47|     167|       7
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   47-  167 (81.74/88.13)	SAREPPNKAQKRVLAINRELPPRNEQFLldfeQIQNQfSDHDQLRAVTESVlislvvqcsghvpraefllfalrslcsisyinwdtflpSLLS.SISSAEV...........................SMGQGSqAAPTvsttnlSQSG
 1245- 1343 (107.41/53.35)	SMRPSHNKAPGTNPPVATSAPESQKAFY....QIQDP.GTYTQLVLETAVI......................................ELLSlPVSAGQIvsslvqivvniqptliqssnnlhvapsSMGQGS.ALPT......SPSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     183.07|      54|     965|     445|     500|       8
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  445-  500 (90.92/58.78)	WWKRVLLVAPGYRSSAQGLS.PGAVFTSEMICEATIDRIFELLKLTNSEIHcwQEWL
 1412- 1466 (92.16/52.03)	WWLSDATRSLGELNSAVGYSlMDPTWAAQDNTSTAIGNTVALLHSLFSNLP..QEWL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.81|      17|      41|     200|     216|       9
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  200-  216 (30.34/17.29)	AQSSIDPSSC.TALSPIK
  239-  256 (25.48/13.31)	AISSLRQLCCkIILSGLK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11799 with Med23 domain of Kingdom Viridiplantae
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