<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11797

Description mediator of RNA polymerase II transcription subunit 8 isoform X1
SequenceMATIDGAVQNQPQQQQPLPAQQVVFAERLNQAVQQQLNLEALKNRATTLFKAISRILEDFDVYGRTNTTPKWQDILGQYSMVNLELFNIVDEIKKVSKAFVVHPKNVNAENSTILPVMLSSKLLPEMEVDDNSKREQLLLGMHNMPVSTQIEKLKTRIEMIGAACESAEKILAETRKAYCFGMRQGPAITPTLDKAQAAKIQEQENLLRAAVNFGEGLRLPGEQRQITSTLPMHLIDVLNAGDGVQSFNETSGMYAKSTPLTSTNISSQGAVIQQPPGSQLVGRSAASPSGATSATSFDNSTSPMPYANSPRSSANIMNTPSPQQQTQQQQQQQLQQVQQRKLMLPQHQQLLAQQQMRQSSMQGIGQIHGQHQMQFSQPLAHQQFQGRQMSSGHVQHGITQSQLGQGNQMNRHLHQFSGAANSSLFNVAQTTPTSQMIPNISATMSSQPLMSRMQHGLPGTNLQRNHASQILSDQMFMGGGSTGGMMPMQQQQQQQQAQLASQGAFGNMPANAQSLQSGMVPLQNMQQTHPNFGQQRQQNQQ
Length542
PositionHead
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.04
Grand average of hydropathy-0.592
Instability index61.73
Isoelectric point9.30
Molecular weight59635.68
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11797
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.81|      26|      27|     324|     349|       1
---------------------------------------------------------------------------
  324-  343 (31.46/ 8.36)	..........QQQTQQQQQQQLQQVQQRKL
  344-  369 (27.29/ 6.09)	MLPQHQqllaQQQMRQSSMQGIGQIH....
  486-  507 (38.05/11.94)	MMPMQQ....QQQ...QQQAQLAS.QGAFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.20|      31|      71|     436|     470|       4
---------------------------------------------------------------------------
  439-  470 (51.44/26.42)	PNISATMSSQ.PLmSRMQHGLPGTNLQRNHASQ
  511-  542 (50.76/18.48)	ANAQSLQSGMvPL.QNMQQTHPNFGQQRQQNQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     103.89|      26|      26|     252|     277|       6
---------------------------------------------------------------------------
  252-  277 (45.92/26.22)	SGMYAKS..TPLTSTNISSQGAVIQQPP
  279-  306 (38.32/20.71)	SQLVGRSaaSPSGATSATSFDNSTSPMP
  418-  433 (19.65/ 7.17)	...........SGAAN.SSLFNVAQTTP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11797 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SFNETSGMYAKSTPLTSTNISSQGAVIQQPPGSQLVGRSAASPSGATSATSFDNSTSPMPYANSPRSSANIMNTPSPQQQTQQQQQQQLQQVQQRKLMLPQHQQLLAQQQMRQSSMQGIGQIHGQHQMQFSQPLAHQQFQGRQMSSGHVQHGITQSQLGQGNQMNRHLHQFSGAANSSLFNVAQTTPTSQMIPNISATMSSQPLMSRMQHGLPGTNLQRNHASQILSDQMFMGGGSTGGMMPMQQQQQQQQAQLASQGAFGNMPANAQSLQSGMVPLQNMQQTHPNFGQQRQQNQQ
247
542










Molecular Recognition Features






MoRF SequenceStartStop




NANANA