<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11796

Description mediator of RNA polymerase II transcription subunit 8 isoform X2
SequenceMATIDGAVQNQPQQQQPLPAQQVVFAERLNQAVQQQLNLEALKNRATTLFKAISRILEDFDVYGRTNTTPKWQDILGQYSMVNLELFNIVDEIKKVSKAFVVHPKNVNAENSTILPVMLSSKLLPEMEVDDNSKREQLLLGMHNMPVSTQIEKLKTRIEMIGAACESAEKILAETRKAYCFGMRQGPAITPTLDKAQAAKIQEQENLLRAAVNFGEGLRLPGEQRQITSTLPMHLIDVLNAGDGVQSFNETSGMYAKSTPLTSTNISSQGAVIQPPGSQLVGRSAASPSGATSATSFDNSTSPMPYANSPRSSANIMNTPSPQQQTQQQQQQQLQQVQQRKLMLPQHQQLLAQQQMRQSSMQGIGQIHGQHQMQFSQPLAHQQFQGRQMSSGHVQHGITQSQLGQGNQMNRHLHQFSGAANSSLFNVAQTTPTSQMIPNISATMSSQPLMSRMQHGLPGTNLQRNHASQILSDQMFMGGGSTGGMMPMQQQQQQQQAQLASQGAFGNMPANAQSLQSGMVPLQNMQQTHPNFGQQRQQNQQ
Length541
PositionHead
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.04
Grand average of hydropathy-0.587
Instability index61.47
Isoelectric point9.30
Molecular weight59507.55
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11796
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     173.31|      24|      26|     346|     369|       1
---------------------------------------------------------------------------
   12-   35 (28.54/ 6.00)	..PQQQ....QPLPAQQvvFAERLNQA.VQQ
  343-  366 (44.30/13.02)	MLPQHQ....QLLAQQQ..MRQSSMQG.IGQ
  367-  393 (34.37/ 8.60)	IHGQHQmqfsQPLAHQQ..FQGRQMSS..GH
  485-  507 (34.02/ 8.44)	MMPMQQ....Q..QQQQ..QAQLASQGaFGN
  508-  527 (32.09/ 7.59)	M.PANA....QSL.QSG..M..VPLQN.MQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.99|      17|      26|     252|     275|       2
---------------------------------------------------------------------------
  252-  268 (30.77/ 9.69)	SGMYAKS..TPLTSTNISS
  278-  296 (21.22/13.40)	SQLVGRSaaSPSGATSATS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.27|      12|     207|     320|     331|       3
---------------------------------------------------------------------------
  320-  331 (25.01/ 9.65)	PSPQQQTQQQQQ
  530-  541 (25.26/ 9.82)	PNFGQQRQQNQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.35|      19|      19|     438|     456|       4
---------------------------------------------------------------------------
  438-  456 (35.71/19.44)	P..NISATMSSQPLMSRMQHG
  458-  478 (30.64/15.67)	PgtNLQRNHASQILSDQMFMG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.69|      32|      39|     135|     172|       6
---------------------------------------------------------------------------
  135-  172 (46.79/38.75)	REQLLLGMHNMP.VSTQIEKLKtriemiGAACESAEKIL
  176-  208 (50.90/29.52)	RKAYCFGMRQGPaITPTLDKAQ......AAKIQEQENLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11796 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SFNETSGMYAKSTPLTSTNISSQGAVIQPPGSQLVGRSAASPSGATSATSFDNSTSPMPYANSPRSSANIMNTPSPQQQTQQQQQQQLQQVQQRKLMLPQHQQLLAQQQMRQSSMQGIGQIHGQHQMQFSQPLAHQQFQGRQMSSGHVQHGITQSQLGQGNQMNRHLHQFSGAANSSLFNVAQTTPTSQMIPNISATMSSQPLMSRMQHGLPGTNLQRNHASQILSDQMFMGGGSTGGMMPMQQQQQQQQAQLASQGAFGNMPANAQSLQSGMVPLQNMQQTHPNFGQQRQQNQQ
247
541










Molecular Recognition Features






MoRF SequenceStartStop




NANANA