<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11777

Description ATP-dependent DNA helicase
SequenceMREDQGNLGDGLKFGGKCPKMNWLEHSKAHKDFSCQKKFLCSNFLFSLPEQKPSTTGATDTGNLACQMQNLQRIQRSQIEKANNKKVFGNHSFRPNQREVINATMSGYDVFVLMPTGGGKSLTYQLPALICPGVTLVISPLVSLIQDQIMHLIQANISAAYLSANMEWSEQQEIFRDLSSDCTKYKLLYVTPEKVAKSDFLLRHLESLNARHLLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPKIPVLALTATATASVKEDVVQALGLINCIIFRQSFNRPNLWYSVIPKTKKCVDDIDKFIKENHFDECGIVYCLSRMDCEKVAERLQECGHKAAFYHGSMDPAQRSFIQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGLRSSCVLYYSYSDYIRVKHMISQGATEQSPLVSGYNRTNLGSSGRILETNTENLLRMVSYCENDVDCRRLLQLVHFGEKFDPGNCKKTCDNCLKSMNLIEKDVTDIAKQLVDLVRSMGQQFSSAHILEVYRGSLSQFVKKHRHEKLSLHGAGKHLLKSDASRILHYLVIEDILVEEVKKNDIYGSVSSLLKVNETKVQSLLNGGQRITLRFPSITKTNKLSKFEMTPAKGSLVFGKMYPNIDTPAQPQSEVDVQLSAKLYSSLRMLRTNLVKEAADGVMAYHIFGNATLQQISRRVPRSKEELLDINGIGKAKVSKYGDRILETIESTINEFYGAGKNGSNSNDSNDSGKRRRGGNKDKDEYLDENDATKSFDRSKKRATNIQSIDPKVHNSSRPEHPDQFFDSELDFDDSHYEIRDLELNNNLDHGNDGRVLPSWS
Length844
PositionUnknown
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.08
Grand average of hydropathy-0.479
Instability index48.55
Isoelectric point8.63
Molecular weight95281.42
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
plasmodesma	GO:0009506	IEA:EnsemblPlants

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:EnsemblPlants
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
cellular response to abscisic acid stimulus	GO:0071215	IEA:EnsemblPlants
cellular response to cold	GO:0070417	IEA:EnsemblPlants
DNA replication	GO:0006260	IEA:InterPro
double-strand break repair via homologous recombination	GO:0000724	IEA:EnsemblPlants









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11777
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     564.49|     156|     274|     299|     456|       1
---------------------------------------------------------------------------
  299-  456 (265.08/180.47)	VDDI.DKFIKENhfDECGIVYCLSRMDCEKVAERLQECGHKAAFYHG....SMDPAQRS..FIQKQWSKDEINIICATVAFG.M..GINKP.....DVRFVIHHSLPKSIEGYHQE...CGRAGRDGLRS..SCVLYYSYSDYIRVKHMISQGATEQSPL..VSGYNRTNLGSSG.RILET
  464-  573 (107.40/65.24)	.................MVSYCENDVDCRRLLQ.LVHFGEK..FDPGnckkTCDNCLKSmnLIEKDVTDIAKQLVDLVRSMG.Q..QFSSA.....HILEVYRGSLSQFVKKHRHEklsLHGAGKHLLKSdaSRILHY...........................................
  576-  731 (192.02/123.78)	IEDIlVEEVKKN..DIYGSVSSLLKVNETKV.QSLLNGGQRITLRFP....SITKTNK........LSKFEMTPAKGSLVFGkMypNIDTPaqpqsEVDVQLSAKLYSSLRMLRTN...LVKEAADG.......VMAYHIFGNATLQQISRRVPRSKEELldINGIGKAKVSKYGdRILET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.14|      24|      45|      36|      62|       3
---------------------------------------------------------------------------
   36-   62 (29.17/30.43)	QKKFLcSNFLFSlPEQKpSTTGATDTG
   84-  107 (43.97/26.15)	NKKVF.GNHSFR.PNQR.EVINATMSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.02|      17|      17|     741|     757|       4
---------------------------------------------------------------------------
  741-  757 (30.00/16.72)	GAGKNGSNSNDSNDSGK
  761-  777 (30.02/16.74)	GGNKDKDEYLDENDATK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.39|      14|     142|      21|      34|       5
---------------------------------------------------------------------------
   21-   34 (27.21/18.07)	MNWLEHSKAHKDFS
  166-  179 (26.18/17.12)	MEWSEQQEIFRDLS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11777 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FYGAGKNGSNSNDSNDSGKRRRGGNKDKDEYLDENDATKSFDRSKKRATNIQSIDPKVHNSSRPEHPDQFFDSEL
739
813










Molecular Recognition Features






MoRF SequenceStartStop




1) GRVLPSWS
2) QFFDSELDFDDSHYEIRDLELNN
837
807
844
829