<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11776

Description ATP-dependent DNA helicase Q-like 4A isoform X3
SequenceMAKEVSMLEISLLFTRTKAFYYTGATDTGNLACQMQNLQRIQRSQIEKAWNALSNFQISCRHYAKLGNTRQVKDVFSDRPADSRRITSNSLSDANASSQHKKVHRHFSEYNVDTTKPSSFRSNLSASRNIKVMEDQNDVDGNNMARLRTINHSHFQRVGDSVSFATNQKNICPSFLEDEDDEIIENIDVDQIVEQYQSQSACTPQPSVSKLPPITPIFEKDNVAKQEESNYPDELCTNCSHGFKIELCPEASSHLQELKDRLISISNDLLDNVNNLSPVQIDKLRQERVHLNKQIQLLERHISLDAVNEERRRSHLFATTVTPKTFHFETPQGAEFRTDAKLNTSYIHQDLEPRRIEPWNSMGSSYVDERFGMSSGPVEREPYIPKVIDVNYIEGSNDKKWSSRNFSWTKELEANNKKVFGNHSFRPNQREVINATMSGYDVFVLMPTGGGKSLTYQLPALICPGVTLVISPLVSLIQDQIMHLIQANISAAYLSANMEWSEQQEIFRDLSSDCTKYKLLYVTPEKVAKSDFLLRHLESLNARHLLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPKIPVLALTATATASVKEDVVQALGLINCIIFRQSFNRPNLWYSVIPKTKKCVDDIDKFIKENHFDECGIVYCLSRMDCEKVAERLQECGHKAAFYHGSMDPAQRSFIQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGLRSSCVLYYSYSDYIRVKHMISQGATEQSPLVSGYNRTNLGSSGRILETNTENLLRMVSYCENDVDCRRLLQLVHFGEKFDPGNCKKTCDNCLKSMNLIEKDVTDIAKQLVDLVRSMGQQFSSAHILEVYRGSLSQFVKKHRHEKLSLHGAGKHLLKSDASRILHYLVIEDILVEEVKKNDIYGSVSSLLKVNETKVQSLLNGGQRITLRFPSITKTNKLSKFEMTPAKGSLVFGKMYPNIDTPAQPQSEVDVQLSAKLYSSLRMLRTNLVKEAADGVMAYHIFGNATLQQISRRVPRSKEELLDINGIGKAKVSKYGDRILETIESTINEFYGAGKNGSNSNDSNDSGKRRRGGNKDKDEYLDENDATKSFDRSKKRATNIQSIDPKVHNSSRPEHPDQFFDSELDFDDSHYEIRDLELNNNLDHGNDGRVLPSWS
Length1176
PositionUnknown
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.08
Grand average of hydropathy-0.556
Instability index52.70
Isoelectric point7.23
Molecular weight133542.26
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
plasmodesma	GO:0009506	IEA:EnsemblPlants

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:EnsemblPlants
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
cellular response to abscisic acid stimulus	GO:0071215	IEA:EnsemblPlants
cellular response to cold	GO:0070417	IEA:EnsemblPlants
DNA replication	GO:0006260	IEA:InterPro
double-strand break repair via homologous recombination	GO:0000724	IEA:EnsemblPlants









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11776
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     159.17|      40|     274|     392|     433|       1
---------------------------------------------------------------------------
   41-   86 (50.02/20.11)	IQRSQiEKAWNAlSNFQISCRHYAklgNTRQVKDVFSDRPaDSRRI
   96-  123 (36.74/16.66)	..ASS.QHKKVH.RHFS...EYNV...DTTK...PSSFRS.N....
  393-  432 (72.42/43.26)	IEGSN.DKKWSS.RNFSWTKELEA...NNKKVFGNHSFRP.NQREV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     315.25|      96|     274|     631|     788|       2
---------------------------------------------------------------------------
  650-  748 (167.69/131.79)	YCLSRMDCEKVAErLQECGHKaaFYHG....SMDPAQRS..FIQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQE...CGRAGRDGLRS..SCVLYY
  799-  905 (147.57/129.25)	YCENDVDCRRLLQ.LVHFGEK..FDPGnckkTCDNCLKSmnLIEKDVTDIAKQLVDLVRSMGQQFSSAHILEVYRGSLSQFVKKHRHEklsLHGAGKHLLKSdaSRILHY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.19|      35|     152|     978|    1016|       7
---------------------------------------------------------------------------
  978- 1016 (46.99/50.19)	PNIDTPAQPQ.......SEVDVQLSAklYS..SLRmLRTNLvKEAADG
 1126- 1169 (53.20/37.77)	PKVHNSSRPEhpdqffdSELDFDDSH..YEirDLE.LNNNL.DHGNDG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.17|      28|     772|     255|     283|      10
---------------------------------------------------------------------------
  255-  283 (40.28/31.49)	LQELKDRLISISNDLLDnVNNLSPVQIDK
 1028- 1055 (44.89/30.03)	LQQISRRVPRSKEELLD.INGIGKAKVSK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11776 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FYGAGKNGSNSNDSNDSGKRRRGGNKDKDEYLDENDATKSFDRSKKRATNIQSIDPKVHNSSRPEHPDQFFDSEL
2) NLSASRNIKVMEDQNDVDGNNMARLRTINH
1071
123
1145
152










Molecular Recognition Features






MoRF SequenceStartStop




1) QFFDSELDFDDSHYEIRDLELNN
2) RVLPSW
1139
1170
1161
1175