<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11772

Description mediator of RNA polymerase II transcription subunit 15a
SequenceMDANNWRPTQGGEPGMEAGDWRSQLQPDSRHRIVNKIMETLKRHLPVSGQEGLSELRKIAVRFEEKIFTAATSQSDYLRKISLKMLTMETKTQPTMGNPLPSNPMVPSNKPLDAASQSMQPPSISVPQSSNQSQQRQQIIPQNIPNNIVPQSSSSLSSAVPPVAGLAPSSMSNMVGQNPNIQNVSGVPQNSGGNAMGQGVPSNVFTNSQRPLQGRQVVPQQQQQQPQTQQQQYLYQQQQQQMHQIMKHKFQQGNMSHPLMQPPHIPQQQQNVMQSNQMQSSQQSVMQPSMMQSSLSNLQQNQQSPIQQSTQSMLQQPPQPVLRQQPQSQQHAVIHQQPTMSQQTNLSSQQQQQLINQQTNSSNMQQSPLIGQQTSVGDMQQQLPQQSRSHGQQSNLSNMQSPPSQQHMAQQSNLSSLQQQQLGPQSNVSGLQQMHGTQSGNSNMQSNQHSMHLLQQNKVQMQQQPPQNTSNLLSTQGQQGQLQSSQQLMSQIPLQSTQVQQQVPLQQQQQQQATAMSHELQQRIPVGGQAPGSLLQSQNVMDQQKQLYHSQRALPETSSTSLDSTAQTGQANGGDWQEEIYQKIKAMRELYFNELKEMYQKILPKVHQYDSLPQQPKLEQLNKLKTFKGILERLLTFLQLSKNSIAIELKDKIGQYEKQIVSFLHSNRPSRNRAPTLQPGQHPTIQPIQQSQSQMTPLQSPENQINPQLHSANMQGSVAPVQQNNMSSMQHNSLPTFSGSAAQQNMTIPMQPGSSLESGQGNSLSSLQQVAAGSLQQNPSNSSQRSNNGSLPSQNVVNTLQQNINSLQSNPNMLQHPHLKQQDPQQLLQSQQLKQMQQRQLKQQVLQHQQHQQHQQQQQQQQQQQPQLHQQQSQLHQQGKQQLPTQMQTHPMSHLNQMEISDLKIRQGLAAKPGMFQHLPATQRAAYTHQQMKPGTSFPISPPIFQAASPQVAQNSSPQVDQQSLLSSITKTGTPLQSASSPFVVPSPSTPMAPSPMPGESEKPTSGVSAHTNAGNAGQQTGVSGTQAQSLAIGTPGISASPLLAECGTDGAYANVLPTVSGKSSFTEQPLERLIKAVKSMSPKALSASVNGIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNFSHDGPNGTKKMRRHTSAMPLNVVSSAGSVNDVFKPLTGAETSDLESTATSSAKRPRVEANHVLLEEIREINQRLIDTVVVISDEVVDPSALAAAADGSEGTVVKCSFSAVALSPSLKSQYTSAQMSPIQPLRLLVPTNYPNCSPILLDKFSVEVSKEYEDLSIKAKSRFSISLRNLSQPMLLRDIARTWDICARAVVSEYAQQSGGGSFCSKYGAWENCLSAA
Length1356
PositionTail
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.03
Grand average of hydropathy-0.751
Instability index75.60
Isoelectric point9.49
Molecular weight148758.98
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11772
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     204.36|      44|      65|     337|     380|       8
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  338-  379 (73.77/21.23)	..........................PTMSQQTNLSSQQQQQLINQQTNSSNMQQSPLIGQQTSVGDM
  380-  444 (49.56/11.00)	QqqlpqqsrshgqqsnlsnmqsppsQQHMAQQSNLSSLQQQQL.GPQSNVSGLQQ..MHGTQSGNSNM
  536-  576 (40.20/ 7.04)	Q.......................sQNVMDQQKQL.YHSQRAL..PETSSTSLDSTAQTGQANG.GDW
  693-  729 (40.83/ 7.31)	.............................SQMTPLQSPENQ..INPQLHSANMQGSVAPVQQNNMSSM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     195.37|      43|      65|     920|     965|       9
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  111-  142 (38.00/ 6.79)	..PLDAASQSMQPPSISvPQ.......SSNQSQQR.........QQI...IP.Q.....
  493-  532 (32.54/ 7.14)	..PLQS............TQVQQQ.V.PLQQQQQQqatamshelQQR...IPvGGQaPG
  941-  974 (40.63/ 7.91)	SPPIFQAASPQVAQNSS.PQVDQQSLlSSIT...................KT.GT....
  975- 1008 (47.40/10.99)	..PLQSASSPFVVPSPS.TPMAPSPM.PGESE..................KP..TS.GV
 1009- 1040 (36.80/ 6.45)	SAHTNAGNAGQQTGVSG.TQA..QSL.....................aigTP.GIS..A
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     113.14|      29|     120|     144|     173|      10
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  144-  173 (49.18/27.49)	IPN..NI..VPQSSSSLSSAVPPvAGLAPSSMSN
  178-  203 (32.84/12.69)	NPNiqNVsgVPQNSG..GNAMG..QGV.PS...N
  277-  297 (31.11/11.53)	...........QMQSSQQSVMQP..SMMQSSLSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.73|      22|     121|     666|     689|      11
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  666-  682 (26.56/ 7.66)	.....SNRPSRNRAPTLQP......GQH
  734-  761 (28.45/11.77)	LPTFSGSAAQQNMTIPMQPgsslesGQG
  804-  823 (33.72/ 9.71)	INSLQSN.PNMLQHPHLKQ.......QD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     159.98|      42|     116|    1093|    1134|      12
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 1093- 1134 (69.84/47.39)	IGSVV....SMIDRIAGS........APGNGSRAAVGEDLVAMTKCR.LQARNFS
 1159- 1206 (42.63/25.97)	AGSVN....DVFKPLTGAetsdlestATSSAKRPRVEANHVLLEEIReINQR...
 1208- 1246 (47.51/29.81)	IDTVVvisdEVVDPSALA........AAADGSEGTV.......VKCS.FSAVALS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.22|      33|     345|     234|     271|      14
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  234-  270 (63.55/32.05)	LYQQQQQQMHQIMkhkfQQGNMSH.............PLMQPP....HIPQQQQ
  875-  924 (46.67/13.26)	LHQQGKQQLPTQM....QTHPMSHlnqmeisdlkirqGLAAKPgmfqHLPATQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.92|      16|      16|    1259|    1274|      17
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 1259- 1274 (29.49/17.61)	SPI..QPLRLLVPTNYPN
 1276- 1293 (22.44/11.65)	SPIllDKFSVEVSKEYED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.12|      25|      26|     593|     618|      18
---------------------------------------------------------------------------
  592-  617 (40.37/32.85)	F...NELKEmYQKILPKVHQYDSLPQQPK
  618-  645 (31.75/19.34)	LeqlNKLKT.FKGILERLLTFLQLSKNSI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.67|      13|      20|      56|      72|      19
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   56-   72 (15.98/26.18)	LRKIAVrfeeKIFTAAT
   78-   90 (22.69/18.73)	LRKISL....KMLTMET
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11772 with Med15 domain of Kingdom Viridiplantae
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