<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11770

Description LOW QUALITY PROTEIN: pre-mRNA-processing protein 40A
SequenceMANNPQYSGLQPLRPPVVGPMDQARSFVPPMNSQFRPAVPAPHSQQFVPMPSPHFQPLGQGVPLMNAGMPPPPPQAQQSQFSQPVAHLPPRPCEPVHGTLPPQTIPLPVAQPNRQFTPELQQVQPLTQPAAIGMPGPGGSGTSLSASYSYGPPQNYNTTIVQPVPQSHAPVVSSGGQLGSLVSVTPLNHSREQPYATSSVTSAANVLPMPSAAAASSEWREHTSPDGRRYYYNKKTKISSWEKPFELMTAIERADASTNWKEFTSPEGRKYYYNKITKESKWIIPEELKLARERVEKSSTLGTEKEPVPLELPSVSTLEAPSTTADTSTTAKELASNALSVAAADLQTDKDASPGTVSSVETNGGVQSPVNIVPSSCAISENDNTAGVVEVTTVEPRNDLNQSSAQDNENLTDGVSAQELEETKKDTSDEKVEFTLEERAIDQETSAYPNKQEAKNAFKALLESANVGSDWTWDRAMRIIINDKRYGALKSLGERKQAFNEFLGQRKNXEVEERRTKQKKAREEFRKMLEESTELTSSMRWGKAESIFENDERFQAVERDRDRRDLFESFLEELKNKERAKAQEERSRNILEYRKFLESCDFIKASSQWRKVQDRLEVDERCSRLEKIDRLEIFQEYLRDLEKEEEEQRKIQKEELRKAERKNRDEFRKMMEEHIAAGLLTPKIHWRDYCMKVKELPAYLAVAANTSGSTPKDLFEDVAEELQKQYRDDKTRIKDAVKLRKVAISLSWTLDDFKTAISKDIGNPPVPDTNLKLVFDELLERAREKEEKEAKKRKRLGDDFFNLLCSFKEISVYSNWEDSKPFFEGSPEYSAIEDERLCKEIFEEYIVQLKEHAKENENKRKEEKARKEREREERERRKEKHKKGEREKEDHFKKDGVDNENVDVSDTLELKENRRLEKERSKKQRKRRYSDEEYSDEDEAGHDRSKKSQSHKDRKKSRRHGSAHESDGESRHRRHKRDHRNGSYKNLDHEELEDGECGDDGASR
Length1004
PositionUnknown
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.07
Grand average of hydropathy-1.088
Instability index56.67
Isoelectric point5.98
Molecular weight114811.42
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11770
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     156.29|      39|      40|     215|     253|       1
---------------------------------------------------------------------------
  215-  253 (79.04/45.73)	ASSEWREHTSPDGRRYYYNKKTKISSWEKPFELMTAIER
  256-  294 (77.25/44.53)	ASTNWKEFTSPEGRKYYYNKITKESKWIIPEELKLARER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     109.82|      17|      19|      13|      29|       2
---------------------------------------------------------------------------
   13-   29 (31.92/14.52)	LRPPVVGPMDQARSFVP
   35-   49 (29.00/12.56)	FRPAVPAPHSQ..QFVP
   50-   63 (25.69/10.34)	MPSPHFQPLGQG...VP
  107-  118 (23.20/ 8.66)	L..PVAQP...NRQFTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     448.10|      82|      83|     828|     909|       3
---------------------------------------------------------------------------
  494-  554 (41.89/15.98)	........ER.......................KQAFNEFLGQRKN.....xeveE......RRTK.........................................QKKAREEFRK.......mlEESTEL.T..SSMRWGKAEsifeNDERF........................
  555-  617 (81.89/38.13)	..QAVER.DRDR.....................RDLFESFLEELK.................NKER..........................................AKAQEERSR.........NILEYR.KflE............SCD.F......I.KASSQWRKVQ..DRLE
  621-  669 (58.66/25.27)	RCSRLEKiDRL.......................EIFQEY...LRDLEKEE....E......EQRK................................................................IQ.K..EELRKAERK....NRDEF......R.K...............
  684-  824 (61.08/26.60)	....IHW.RDYCmkvkelpaylavaantsgstpKDLFEDVAEELQKQYRDD....K......TRIKdavklrkvaislswtlddfktaiskdignppvpdtnlklvfDELLERAREK.........EEKEAK.K..RK.....RL....GDDFFnllcsfK.EISVYSNWEDSKPFFE
  828-  909 (137.75/69.05)	EYSAIED.ERLC.....................KEIFEEYIVQLKEHAKEN....E......NKRK.........................................EEKARKERER.........EERERR.K..EKHKKGERE....KEDHF......K.KDGVDNENVDVSDTLE
  912-  995 (66.83/29.79)	ENRRLEK.ERSK.....................KQRKRRY..SDEEYSDED....EaghdrsKKSQ.........................................SHKDRKKSRRhgsahesdgESRHRRhK..RDHRNGSYK....NLDHE......ElEDG.............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     175.36|      41|      42|     125|     165|       4
---------------------------------------------------------------------------
   65-   92 (45.89/21.10)	......MNA.GMPPPPPQAQQSQFSQPVA..................HLP.......PRP
   97-  137 (34.35/14.06)	HGT...........LPP........QTIPlpvaqpnrqftpelqqvqPLTQPAAIGMPGP
  138-  177 (58.42/28.74)	GGSGTSLSA.SYSYGPPQNYNTTIVQPVP..............qshaPV.....VSSGGQ
  178-  214 (36.70/15.49)	LGSLVSVTPlNHSREQP..YATSSVTSAA...............nvlPMPSAAA......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.59|      19|      24|     369|     388|       6
---------------------------------------------------------------------------
  369-  388 (30.92/24.73)	PVNIVPSSCAiSENDN.TAGV
  396-  415 (30.67/19.27)	PRNDLNQSSA.QDNENlTDGV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11770 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ENDNTAGVVEVTTVEPRNDLNQSSAQDNENLTDGVSAQELEETKKDTSDEKVEFTLEERAIDQETSAYPNKQEAK
2) ERVEKSSTLGTEKEPVPLELPSVSTLEAPSTTADTSTTAKELASNALSVAAADLQTDKDASPGTVSSVETNGGVQSPVNIVPSSCAI
3) HAKENENKRKEEKARKEREREERERRKEKHKKGEREKEDHFKKDGVDNENVDVSDTLELKENRRLEKERSKKQRKRRYSDEEYSDEDEAGHDRSKKSQSHKDRKKSRRHGSAHESDGESRHRRHKRDHRNGSYKNLDHEELEDGECGDDGASR
4) MANNPQYSGLQPLRPPVVGPMDQARSFVPPMNSQFRPAVPAPHSQQFVPMPSPHFQPLGQGVPLMNAGMPPPPPQAQQSQFSQPVAHLPPRPCEPVHGTLPPQTIPLPVAQPNRQFTPELQQVQPLTQPAAIGMPGPGGSGTSLSASYSYGP
5) QNYNTTIVQPVPQSHAPVVSSGGQLGSLVSVTPLNHSREQPYATSSVTSA
381
293
852
1
154
455
379
1004
152
203










Molecular Recognition Features






MoRF SequenceStartStop




1) DMKGAGIDRRKRK
188
200