<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11764

Description mediator of RNA polymerase II transcription subunit 33B-like isoform X1
SequenceMAVSAQPPGQLQGIAGLWDTVLEVTKSAQDKNCDPLLWAVQLSSTLNSAGVSLPSVELAQLLVSHICWDNHVPIMWKFLEKAMTARIVPPLLVIALLSTRAIPYRKLQPAAYRLYLELLSRHVFSSTSQIYGPNYQRIMQTIDDVLHLTQIFGLQTCEPGVLMVELFFSIVWQLLDASLDDEGLLALPGEEKSAWLIRPQLHDMELDVHDSFGEKKTENSESLLKVNTAKAIEIIGQFLQNKKTERILCLALRNMPLQWAGFAQRLQLLGANSVVLGNAKLITPEVLLHWTSDKNKLLSQKGKTSQLEFRDVMSSGSLFSSAGQSHGVNWSALWLPIDLFLEDAMDGSQVLATSAVERLICLIKSLRAVNDTSWHNTFLGLWIAALRLIQRERDPSEGPVPRLDTCLCMLLSISTLAVTIIIEEEEVEPKEDDCSPSKSRDEKQSSGMCRKGLITSLQMLGEYESLLTPPQSIIAVANQAAAKAVMFISGVAVGNEYYDCASMNDAPINCSGNMRHLIVEACISRNLLDTSAYFWPGYVNALSSQVPRSASNQVVGWSSFMKGSPLTPSMVNALVATPASSLAEIEKIYEIAINGSGDEKISAASILCGASLVRGWYLQEHTALFISRLLLPPIPTDYSGSDSYLIDYAPFLNVLLVGISSVDCVQIFSLHGMVPLLAGQLMPICEAFGSSPPKSWILTSGEELTCHAVFSLAFTLLLRLWRFHHPPVENVKGDARPVGSQLTPEYLLLVRNSQLASFGKSPNDRLKARRLSKLLKFSLQPIFMDSFPKLKGWYRQHQECIASILSGLVPGAPVHQIVDALLTMMFRKINRGGQSLTSTTSGSSNSSGSANEEASIKLKVPAWDILEATPFVLDAALTACAHGRLSPRDLATGLKDLADFLPASFATIVSYFSAEVTRGIWKPAFMNGTDWPSPAATLSIVEQQIKKILAATGVDVPCLAVGGSSPAMLPLPLAALISLTITYKLDKASERLLALVGPALNSLAASCSWPCTPIIASLWAQKVKRWNDFLVFSASRTVFHHNSDAVVQLLKSCFTSTLGLGNSNGNNSGGVGTLLGHGFGSHVLGGMSPVAPGILYLRVHRSVRDVLFVVEEIVSLLMLSVRDIAVSGLPKEKAEKLKKTKYGMRYEQVSFASAMARVKLAASLGASLVWISGGSGLVQSLFKETLPSWFLSVHSVEREGVNYGGMVAVLRGHALAFFSVLCGTFSWGIDSSSSASKRRAKILDSYLEFLASALDGKFSIGCDWATWRAYVSGFVSLIVRCAPRWLLEVDLNVLTRLSNGLRQLNEEELGLELLESGGVNAMGAAAELIIEGGF
Length1334
PositionTail
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.08
Grand average of hydropathy0.195
Instability index40.85
Isoelectric point6.52
Molecular weight145069.25
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11764
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     255.26|      66|     158|     993|    1058|       1
---------------------------------------------------------------------------
  993- 1052 (96.48/56.09)	...............................LALVGPALNS.LAASCSWPC....TPIIASLWAQKVKRW...NDFL.VFS.ASRTVFHH........NSDAV.VQLLKS
 1053- 1077 (23.39/ 7.58)	CFTSTL....................................................................................glgnsngnNSGGV.GTLLGH
 1155- 1212 (70.90/39.11)	...............................MARVKLA.AS.LGASLVWIS..ggSGLVQSLFKETLPSW.....FLsVHS.VEREGV..........NYGGM.VAVLRG
 1216- 1316 (64.48/34.85)	AFFSVLcgtfswgidssssaskrrakildsyLEFLASALDGkFSIGCDWATwrayVSGFVSLIVRCAPRWlleVDLN.VLTrLSNGLRQL........NEEELgLELLES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.24|      25|      30|     378|     406|       2
---------------------------------------------------------------------------
  378-  406 (39.10/40.41)	FLGLWIAALRLIQRERDPSegpvPRLDTC
  410-  434 (40.14/28.79)	LLSISTLAVTIIIEEEEVE....PKEDDC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.11|      38|     157|      72|     119|       3
---------------------------------------------------------------------------
   72-  119 (51.80/56.49)	VPIMWKFLEKAMTARIvpplLVIALlstRAIPyrkLQPAAYRLYLELL
  232-  269 (69.31/43.45)	IEIIGQFLQNKKTERI....LCLAL...RNMP...LQWAGFAQRLQLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.15|      31|     156|     439|     470|       4
---------------------------------------------------------------------------
  439-  470 (53.03/38.78)	SRDEKQS..SGMCRKGLITSLqMLGEYES.....LLTPP
  596-  633 (47.12/29.21)	SGDEKISaaSILCGASLVRGW.YLQEHTAlfisrLLLPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.10|      13|      31|     536|     549|       5
---------------------------------------------------------------------------
  536-  549 (20.33/17.30)	PGYVNALSSqVPRS
  568-  580 (23.76/14.64)	PSMVNALVA.TPAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     178.36|      54|     164|     144|     198|       6
---------------------------------------------------------------------------
  144-  198 (88.77/50.97)	DVLHLTQIFGLQTCEPGVLMVELFFSIVWQLLDAsLDDEGLLALPGEEKSAWLIR
  311-  364 (89.59/47.95)	DVMSSGSLFSSAGQSHGVNWSALWLPIDLFLEDA.MDGSQVLATSAVERLICLIK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.05|      20|      23|     916|     935|       8
---------------------------------------------------------------------------
  916-  935 (40.33/25.47)	VTRGIWKPAFMNGTDWPSPA
  941-  960 (33.72/20.07)	VEQQIKKILAATGVDVPCLA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11764 with Med33 domain of Kingdom Viridiplantae
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