<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11757

Description mediator of RNA polymerase II transcription subunit 25
SequenceMADKQLIVVVEGTAAMGPFWQTVVSDYIEKIVRSFCGNELTGQKPPTSNVEFSLVTFHTHGSYCGCLVQRTGWTRDVDIFMQWLSAIPFSGGGFSDAAIAEGLAEALMMFPTQPNGGQNQQTMDMQKHCILIAASNPYPLPTPVYRPAVQNLEQHDNVEPGSSQSYAETVAKSFSQCFISLSVICPKQLPKLRAIYTAGKRNPRAADPPIDNVKTPSYLVLISENFVEARAALSRPGITSLPANQSPVKMDISPVVPVTGPPPTTTPSVNGPIINRQPVSVTNGPPATVKVEPNTVTSMTNGSGYPPHMPSVVRAASQGVPSLQTSSPLSSQEMITNNENTQDLKPLVNGVPQPVRSLGPANVSILNNISQARVMSTAALNGGTSIGLPSMGQTPIAMHVSNMISSGMGSSVPAAQNVFSSGQSGMTSINGSSTLSQVAPNSGISSLTSGNNNISGNPNIATSQAVGNLQGSVSVSQSVPGISQGNLAGTQVVQSGIGVSQNVMSNLTQPGVSSGNGTMIPTPGMPQQVQNGMHSLGVNNAAANMPLPQHSAGALQQAQSKYVKFWEGNLSGQRQGQPVFITRMEGYRSASASDKLAANWPQTMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLGQLQEKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDMVVFKPQISSQQQQQHQMQQQQMQQQQMQQQLQQQQQHQLSQLQQHQLPQMQQQQQQQQQQQQPQLPHMQQQQQQQQQQQSQLPQIQQQQQQQQQQTQLSQLQSQQQPQLSQLQSQQQIPQMQQQQQQMVAGGMSQSYVQGGRSQLVSQGQVSSQGQSNMSAGNFMG
Length843
PositionUnknown
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.04
Grand average of hydropathy-0.435
Instability index61.46
Isoelectric point9.00
Molecular weight90862.44
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11757
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     116.87|      17|      17|     720|     736|       1
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  720-  736 (42.38/11.61)	QQHQLPQMQQQQQQQQQ
  738-  754 (40.42/10.76)	QQPQLPHMQQQQQQQQQ
  755-  769 (34.07/ 8.03)	QQSQLPQIQQQQQQ..Q
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     102.09|      19|      68|     701|     719|       3
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  701-  719 (40.59/13.53)	QQQMQ.QQLQQQQQHQLSQL
  770-  789 (31.41/ 8.57)	QQQTQlSQLQSQQQPQLSQL
  792-  805 (30.10/ 7.86)	QQQIP.Q.MQQQQQ....QM
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     448.86|      81|      83|     390|     470|       4
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  245-  300 (67.20/22.26)	...QS......................PVKMDISPV........VP....VTGPPPTTTPSVNG........P...iiNR.QPVSVTN....GpP....ATVKVEPNT....VTS..................MT
  303-  385 (91.07/32.70)	S.GYP......................P...HMPSVVRAA.SQGVPSLQT..SSPLSSQEMITNNENTQDLKPlvngvPQ.PVRSLGP....A.NvsilNNISQARVM....STAA.............LNGGTS
  390-  470 (134.72/51.79)	SMGQT......................PIAMHVSNMISSGMGSSVPAAQNVFSSGQSGMTSINGSSTLSQVAP.....NS.GISSLTS....G.N....NNISGNPNI....ATSQ.............AVGNLQ
  474-  556 (78.80/27.33)	SVSQSvpgisqgnlagtqvvqsgigvsQNVM..SNLTQPGV...........SSGNGTMIPTPG...MPQQVQ.....N..GMHSL......G.V....NNAAANMPL....PQHS.............A.GALQ
  557-  653 (77.06/26.57)	QAQSK......................YVKFWEGNLSGQRQG......QPVFITRMEGYRSASASDKLAANWP.....QTmQIVRLISqdhmN.N....KQYVGKADFlvfrAMNQhgflgqlqekklcAVIQLP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     139.55|      44|      50|     128|     176|       5
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  113-  156 (79.02/42.82)	QPNGGQN.QQTM..DMQKHCILIAASNPYPLPT..PVYRPAVQNLEQHD
  159-  207 (60.52/46.15)	EPGSSQSyAETVakSFSQCFISLSVICPKQLPKlrAIYTAGKRNPRAAD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11757 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) INGSSTLSQVAPNSGISSLTSGNNNISGNPNIATS
2) LSRPGITSLPANQSPVKMDISPVVPVTGPPPTTTPSVNGPIINRQPVSVTNGPPATVKVEPNTVTSMTNGSGYPPHMPSVVRAASQGVPSLQTSSPLSSQEMITNNENTQDLKPLVNGVPQPVRSLGPANV
3) VMSNLTQPGVSSGNGTMIPTPGMPQQVQNGMHSLGVNNAAANMPLPQHS
429
233
503
463
363
551










Molecular Recognition Features






MoRF SequenceStartStop




NANANA