<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11748

Description mediator of RNA polymerase II transcription subunit 16
SequenceMTQVSNATEGEEQPQVQPLELPKVSDKTEPLPAQEEVMEKPDDSMDEDLVTPATVFRIKLKQPRSNLQHKMSVPELCRNFSAVAWCGKLNAIACASETCARIPSSNANPPFWIPIHIVIPERPTECAVFNVIADSPRDSVQFIEWSPTSCPRALLIANFHGRTTIWTQPSRGPANLVRDASCWQLEHEWRQDIAVVTKWLSGLSAYRWLSSKSNSSNSKPNFEEKFLPQQSQTSARWPNFLCVCSVFSSGSVQLHWSQWPPSQNSSPPKWFCTSKGLLGAGPSGIMAADAIITDSGAMHVAGVPIVNPSTVVVWEVTPGPGNGFQATPKTNTSNGVPAPLSPPNWSGFAPLAAYLFSWQEFLLSELKQGKKQTDQDVNDTIPLHCSPVSNFSAYVSPEAAAQSATTTTWGSGVTAVAFDPTRGGSVIAIVIVEGQYMSPYDPDEGPSISGWRVQRWESSLQPVVLHQIFGSPTASFSGQAPTQTVWLSKVDTSISPTSDFKSNQSAVSGPNSDLRKLSGAYIDKAKKVCFDPFDLPSDVRTLARIVYSAHGGEIAVAFLCGGVHVFSGPNFAPVENYQINVGPAIAAPAFSSTSCCSASVWHDVNKDCTMLRIIRVLPPAAPSNQLKANSSTWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSPNSVIAVLDADFHSLPSSQHRQQYGPSLDRIKCRLLEGTNAQEVRAMVLDMQARLLLDMLGKGIESALINPSALLSEPWHASGETLSGIDPEAMAVEPALIPSIQAYVDAVLDLASHFITRLRRYASFCRTLASHAVTAGTGSNRNIVASPTPSSASPATSQGAQSSTTSTTGSTQMQAWVQGAIAKISSTTDGVTSSTPNPISGSSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLPRYIGNSQRNADANIQKPQPAVPGKVEEINSNSVKPVQNIVKPDESQIVRASQLVTGAKGAEEGLAGRSRIGTGNAGQGYTSEEVKVLFLILIDLCRRTASLPHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMYGGPWSDVDDLGPNDDSSKLSNSSDPLDLNSLENCNVYYGANGLWPRKRRMSERDAAFGLNTSIGLGAFLGIMGSRRDVVTAVWKTGLEGVWYKCMRCLRQTSAFASPGATNDTTQNERETWWISRWAYGCPMCGGTWVRVV
Length1237
PositionTail
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.08
Grand average of hydropathy-0.207
Instability index46.21
Isoelectric point6.19
Molecular weight134087.89
Publications
PubMed=22753475

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process
circadian regulation of gene expression	GO:0032922	IEA:EnsemblPlants
positive regulation of plant-type cell wall cellulose biosynthetic process	GO:2001011	IEA:EnsemblPlants
positive regulation of systemic acquired resistance	GO:1901672	IEA:EnsemblPlants
regulation of cell wall pectin metabolic process	GO:1902066	IEA:EnsemblPlants
regulation of ethylene-activated signaling pathway	GO:0010104	IEA:EnsemblPlants
regulation of jasmonic acid mediated signaling pathway	GO:2000022	IEA:EnsemblPlants
regulation of long-day photoperiodism, flowering	GO:0048586	IEA:EnsemblPlants
regulation of transcription, DNA-templated	GO:0006355	IEA:EnsemblPlants
response to osmotic stress	GO:0006970	IEA:EnsemblPlants
root development	GO:0048364	IEA:EnsemblPlants
trichome branching	GO:0010091	IEA:EnsemblPlants
trichome papilla formation	GO:1905499	IEA:EnsemblPlants









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11748
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     241.84|      81|     318|       2|      93|       1
---------------------------------------------------------------------------
    2-   93 (118.44/131.37)	TQVSNATEGeeQPqvQPLELPKVSDkTEPLPA.....QEEV...MEKPDDSMDEDLVTpatvfRIKLK.QPRSNLQHKMSvPE.LCRNFSAVAWCGKLNAIA
  327-  417 (123.41/97.42)	TPKTNTSNG..VP..APLSPPNWSG.FAPLAAylfswQEFLlseLKQGKKQTDQDVND.....TIPLHcSPVSNFSAYVS.PEaAAQSATTTTWGSGVTAVA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     592.92|     156|     245|     425|     599|       2
---------------------------------------------------------------------------
  425-  585 (259.91/160.36)	SVIAIVIVegqyMSPYDPDE..GPSISGW.............R...VQR.WESSLQPVVLH..........QIFG.SPTASFSG.QAPTQTVWLSKVDTSISPTSDFKSNQSAVSGPNSD...LRKLSGAYIDKAKKVCFDPFDLPSDVRTLARIVYSAHGGEIAV....AFLCGGVHVfSGPNFAPVENYQINVGPAI
  609-  768 (201.11/96.86)	TMLRIIRV....LPPAAPSNqlKANSSTW.............EraiAERfWWSLLVGVDWW..........DAVGcTQSAAEDGiVSPNSVIAVLDADFHSLPSSQHRQQY....GPSLDrikCRLLEGTNAQEVRAMVLD.....MQARLLLDML..GKGIESALinpsALLSEPWHA.SGETLSGIDPEAMAVEPAL
  770-  900 (131.90/60.15)	.......................PSIQAYvdavldlashfitR...LRR.YASFCRTLASHavtagtgsnrNIVA.SPTPSSAS.PATSQ.....GAQSSTTSTTGSTQMQAWVQGA......IAKISST.TDGVTSSTPNPISGSSTFMPIS.INTGTFPGTPAV....R.LIGDCH.....................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.33|      22|     113|     126|     151|       4
---------------------------------------------------------------------------
  126-  151 (39.00/27.06)	CAVFNviadSPRDSVQFIEWSPT..SCP
  244-  267 (40.32/19.68)	CSVFS....SGSVQLHWSQWPPSqnSSP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11748 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MTQVSNATEGEEQPQVQPLELPKVSDKTEPLPAQEEVMEKPDDSMD
2) SNRNIVASPTPSSASPATSQGAQSSTTSTTG
1
811
46
841










Molecular Recognition Features






MoRF SequenceStartStop




1) EEQPQVQPLELPKVS
2) KTEPLPAQEE
11
27
25
36