<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11747

Description LOW QUALITY PROTEIN: cyclin-dependent kinase E-1
SequenceMGDGNNSNRGLVSANAASRNNNNNNNNGSHHKKPEWLQQYDLIGKIGEGTYGLVFLAKIKPPSPSRGKSIAKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINHADMSLYLAFDYAEHDLYEIIRHHRDKANHPLNQYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGEEQGVVKIADFGLARIYQAPLKPLFENGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGQEVKGPPNPFQLDQLDKIFKVLGHPTIEKWPTLANLPNWQQDVQHIQGHKYDNAGLYNVVHLSPKSPAYDLLSKMLEYDPRKRITAAQALEHEYFRLEPLPGYNALVPNQPGEKVINYPTRPVDTTTDFEGTTSLQPSQTVTSGNAVNMQGGHMARSVPRAMGVGMPRMPHQGMAAYNLASQAGMGMNPGGIPMQRGVSSQAHQQQQLRRKDPGMGMPGYPPQQKQQRRY
Length485
PositionKinase
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.08
Grand average of hydropathy-0.536
Instability index40.13
Isoelectric point9.31
Molecular weight54298.32
Publications
PubMed=22753475

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP11747
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.94|      30|      42|     178|     209|       1
---------------------------------------------------------------------------
  178-  209 (47.53/33.86)	LVMGEGEEQGVVKIADFGLarIYQA..PLKPLFE
  223-  254 (49.40/29.34)	LLLGAKHYTSAVDMWAVGC..IFAEllTLKPLFQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.10|      25|      42|     317|     346|       2
---------------------------------------------------------------------------
  317-  346 (32.01/33.70)	LSPKSPAydllSKMLEYdPRKRITAAQALE
  361-  385 (45.09/28.51)	LVPNQPG....EKVINY.PTRPVDTTTDFE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.61|      15|      42|     393|     407|       3
---------------------------------------------------------------------------
  393-  407 (25.64/12.83)	SQTVTSGN..AVNM....QGG
  410-  428 (19.89/ 8.54)	ARSVPRAM..GVGMprmpHQG
  436-  452 (23.08/10.92)	SQAGMGMNpgGIPM....QRG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP11747 with CDK8 domain of Kingdom Viridiplantae

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