<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11741

Description U-box domain-containing protein 33-like isoform X2
SequenceMAVVSAVQATTPRVGPINYAEASPIMISSSREIVEEPVGAVSEDIIYVAVGKDVKECLSVLRYALKSSRGKKICLLHVHVPAQMIPLMGTKFPANSLEKEEVKAYHEFEKQNLPRVMNEYILYCLQEGVHADKLCGEAKYIEKGIVDMISLHRIDKLVMGAAVDKCYSRKMVDLKSKKAIYVRSQAPAFCHIEFICKGNLICTREGISDEAQVETIISSPQISPDAESSEVTHRRSQSLPLGQDNSREVGSPSSSLRPRGRSLLLDHFRGNILDPSSPDIRSGVHAARNLEVNEAKDEWGLLTRRSPSERSENSTRSPRGVIDMAPSPFFRVELCANGLEDGNTSDNLYNQCERVMMEAANARREAFLEAIARRKSEKETVNALHRVRVAEGLYAEELKQRKEVEQELAKEKAKLESIKTQLNEEMEELRIAQDQKASLERDLLEADLTAKELEQKILSAVELLQSYKREREELQIQRDNALREAEELRENQSTGRDLTQFFTEFPFREIEEATKNFDPSLKIGEGGYGSIFRGNLRHTMVAIKILHSDSSQGPSEFQQEVNVLSKMRHPNLVTLIGACPEAWVLIYEYLCNGSLEDRLSCKDNTPPLSWQIRIRIATELCSALMFLHSSKPHSIIHGDLKPANVLLDANFVCKLGDFGICRLLSRDEMLNSETLVWRTDNPKGTFAYMDPEFLSSGELTTKSDVYSFGIILLRLLTGRSAMGISKEVQYAMANGNLESILDPLAGDWPFVQAEQLARLALRCCDMKRKSRPDLITDVWRVLGPMRASCGGRLSIQLGSAEHSQPPSYFICPIFQEVMQDPHVAADGYTYEAEAMRGWLDSGHDTSPMTNLKLEHRNLVPNRALRSAIQEWLHHN
Length875
PositionTail
OrganismCucumis melo (Muskmelon)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.06
Grand average of hydropathy-0.385
Instability index49.56
Isoelectric point5.87
Molecular weight98417.17
Publications
PubMed=22753475

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP11741
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     183.11|      63|     465|     173|     242|       1
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  173-  242 (91.00/73.90)	DLKSKKAIYvrsQAPAFCHI.EF.ICKgnLICTREGISDEAQVETiISSPQ.....ISPDAESS.EVThRRSQSLPLG
  639-  709 (92.10/53.61)	DLKPANVLL...DANFVCKLgDFgICR..LLSRDEMLNSETLVWR.TDNPKgtfayMDPEFLSSgELT.TKSDVYSFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     280.17|      89|     261|     247|     347|       2
---------------------------------------------------------------------------
  247-  347 (139.88/112.79)	REVGSPSSSLRPR...GRSLLLDHFRGNiLDPSSPDIRSgVHAARNLEVNEAKDEWGLLTRrspsersensTRSPRGV..IDMAPSPFFRV..ELCANGLEDG.NTSDN
  508-  604 (140.29/86.96)	REIEEATKNFDPSlkiGEGGYGSIFRGN.LRHTMVAIKI.LHSDSSQGPSEFQQEVNVLSK..........MRHPNLVtlIGACPEAWVLIyeYLCNGSLEDRlSCKDN
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.43|      32|      34|     375|     408|       4
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  375-  408 (44.14/43.13)	KSEKETVNALHRVRVAEGLYAEElkQRKEVEQEL
  412-  443 (48.29/39.39)	KAKLESIKTQLNEEMEELRIAQD..QKASLERDL
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP11741 with Med32 domain of Kingdom Viridiplantae

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