Description | Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MSSAGVSAGRQAEDALPQSAEPPLPDMKPLPPAQPPPPVAAPQPAPRPQSPAGVKEEENYSFLPLVHNIIKCMDKDSPDIHQDLNALKTKFQEMRKVIGTMPGIHLSPEQQQQQLHSLREQVRTKNELLQKYKSLCMFEIPKE |
Length | 143 |
Position | Middle |
Organism | Erinaceus europaeus (Western European hedgehog) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Eulipotyphla> Erinaceidae> Erinaceinae> Erinaceus. |
Aromaticity | 0.03 |
Grand average of hydropathy | -0.719 |
Instability index | 91.87 |
Isoelectric point | 6.42 |
Molecular weight | 15905.12 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP11716 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) AEDAL 2) PQSPAGVKEEENYSFLPLVHNI | 12 48 | 16 69 |
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