<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11700

Description mediator of RNA polymerase II transcription subunit 12-like isoform X1
SequenceMQTLLDDFFSKNTSQSTPHNRDQSPQMSYATSLKHRSSQLLPVSDGEEPSLHFRWWYVVRLLQWHHTEGLLLPSLVIDWIFHQLQEKQLLEIWQLFLPIVYGFLEIVVLSQTYVRTLAGVALSIIRDPAPGGSDLVDNSRRAYTAAALIEMLQYLIFAVPETFVTLDCFPLPFSVVSHTINDGNFVPKAIEAAEKIKNSSEDVVCTFRSKGLDAKYESLAFGRVISCIQKHAENLTKAVSPGYPGHCLAKAAQALDKSLVLGDIRGAYTFLFEDLYDGRSSEGWVAKISPCLRLSLKWFVNVNSSLVYSVFFLCEWATSDFRDFRTAPPCDIKFTGKKDLSQVHIAVRLLKMKLRNMHISSRQRNENTHHGVDYSAKCSSQHINWNNASKIKSSSKSMNQSICSSVIFESPGPLHDIIVCWIDQHVVHKGVGFKCLHLFIVELILAGIFYPLAYVRQLIVSGIMDTSVNMVELERQKRHCQILKQLSGNFVRHALEESEIIEGPLLIEALHVYLNERRLILRGSFSENHINGSSRANNSTVNKKHCTSSAKDGFSTVSIDQQKTVPSNKISDKVEKDNTCVENLKTAISVLLQLPKSLPNPNTTELGESQGSVKRLVRCYSKIDLMEATPGCEECRRAKKQKLSEERSSLDVEDTWWVKKGLKSLEPLKVDQPLKTTKQVTKSRHKTVRKTQSLAQLAASRIEGSQGASTSHVCDIKVSCPHHRTAMDGDTAKSVDGIRTSQYQDIVSLGRALKRLRFVEKKEITVWLMTVIRQFIGDSEKSIGKVGQFGRPVTTMDDRSSIRWKLEEDELSAILYLMDVSDDLVPAIKFLLWLLPKVCSSSNSTIHSGRNVLMLARNVDNQVCNVGEAFLLSSLRRYENILASADLIPEALSSVMDRAAAIIASNGRVSGSGALAFARYLLKKYSNVVSVIEWEKNFKTTCDKRLASEFESGGRLVDGEFGLPLGVPAGIEDPDDYFRQKISGGRLPSRVASGMRDVVQRNVEDAFHYLFGKDRKLFAAGSPKGFSLEKWDNGYQIAQHIVIGLIDCIRQTGGAAQEGDPSLVTSAVSAIVGSVGPSLAKLPDFSAGNNHPNISLATSSLNYAKCILRMHITCLCLLKEALGERQSCVFDIALAIEASNALAGVFAPSKASRSQFQMSPETDDTSATMSNDVVNSSSKIVLARTTKIASSVSALIVGAIIYGVTSLERMVTILRLKEGLDVVQFVRNSRSNSNGNARSTGAIKVDSSVEVHLHWFRLLVGNCRTICEGLVVDLLSEPSIVAFSRMQRTLPQRLVFPPAYSIFSFVIWRPFITSANVANREDTNQLYQTLTMAINDAMKHLPFRDVCLRDSQGLYDLIAADTSDLEFANLLELNGSDMRLNSTAFVPLCARLFLNAMVDCKMPQSIYTKDGGSCISGHGESKIHFTDSESKLQDQLVDVLEALQPAKFHWQWVELRLLLNELALIEKLQTHNVSLADAIQLSLPSSEKAAASENENNFIQILFTRLLVRPDAAPLFSELVHLFGKSLEDSMLLQAKWFLGGEDVLFGRKTIRQRLINIAETKGFSVKPHSLEPWGWCSPSTDPLTIKGGKRKVDSLSLEEGEVVEEGVNVKRSIKGFSQVFDSEGSTIKQQHGTERAFLELILPCIDQSSNESRYSFASGLIKQLSYIEQQIAVVTCGPGNPAASMPVTEGQTNKGNSRKTIKGGSLGLARRPTSSTDSSPPSPAALRASMSLRIQLLMRFLPILCTDGEPSVRNMRRTLASVTLRLLGSRIVLEDANILVNATHSSLSKKDAESPSKVAYAAFVDSSVEGLFERLLLMLHGLLSSSPPSWLRLKPVSKTTTNEPTRDLSGVDRELLETLQV
Length1862
PositionKinase
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.07
Grand average of hydropathy-0.123
Instability index48.26
Isoelectric point8.50
Molecular weight206190.06
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11700
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     213.45|      72|     377|    1377|    1456|       1
---------------------------------------------------------------------------
 1377- 1456 (113.63/90.89)	DMR..LNSTAFVPLCARLFL...NAMVDCKMpQSIYTKDGGScisghgESKI...HFTDSESK.LQDQLVDVLEALQPAKfHWQWVELR
 1755- 1835 (99.82/59.19)	NMRrtLASVTLRLLGSRIVLedaNILVNATH.SSLSKKDAES......PSKVayaAFVDSSVEgLFERLLLMLHGLLSSS.PPSWLRLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     158.47|      52|     378|    1208|    1263|       2
---------------------------------------------------------------------------
 1208- 1263 (80.48/70.60)	ERMVTILRLKEGlDVVQFVRNSRSNSNGNAR...STGA.IKVDSSVEvhlHWFRLLVGNC
 1590- 1645 (77.99/54.99)	KRKVDSLSLEEG.EVVEEGVNVKRSIKGFSQvfdSEGStIKQQHGTE...RAFLELILPC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.92|      37|     378|     223|     333|       3
---------------------------------------------------------------------------
  277-  316 (61.03/149.56)	DGRSSEGWvaKISPCLRLSLKWFVNVNSSLVYSVFFLCeW
  797-  833 (64.89/12.78)	DDRSSIRW..KLEEDELSAILYLMDVSDDLVPAIKFLL.W
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11700 with Med12 domain of Kingdom Viridiplantae
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