<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11695

Description mediator of RNA polymerase II transcription subunit 25 isoform X2
SequenceMAEKQLIVVVESTAAMGPYWDTLQMDYIEKIVRCLCGNESSGQKPSVSNVEFALVTYNTHGCYSGILVQRTGWTKDPDVFLQWLSSVPFSGGGFNDVAIAEGLAEALMMFPHSQSGGPNQQSADMHMHCILVAASNPYPLQTPVYVPQLQSLEQSESVDSEPGKQLYDAEAVAKVFPQFSISLSIICPKQLPKVKAVYNAGKRNNRAADPPVDAKTSHFLILISEGFREARGALSRSGITNLPSNQSPVKVDTVSVTPVTGGPPTSLPSVNGTIANRQPIPAGNVTPATVKVEQVPVTSMITGPAFPHNSSAARATSTGQGNPSLQASSPSSVSQDIMTSNENAQDTKPIVSMLQPLRPVNPAQVNGNILNNLSQARQVAQNTGLASLTSATSNLSSSSNTGISQSLANLQGAVSMGQQASGMNPGNLSGAQMVQGGVNMNQNVMNGLGQSVVSSGNGAMIPTPGMPQQVQSGMQPLVNNAASANLPLSQQTSAQSKYIRVWEGSLSGQRQGQPVFITKLEGYRSSSASETLAANWPPVMQIVRLISQDHMNNKQYVGKADFLVFRAMNPHGFLGQLQEKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDMVVFKPQLSSQQQQMQQQHQQMQSQQQHLPQLQQQQQLPHMPQQLQQQQQQLPQLQQQQQQQLSQLQQQQLPQLQQQQLSQLQSQQQQLPQLQQLQQQQMVGAGMGQTYVQGPGRSQMVSQGQVSSQGATNIGGGNFMS
Length751
PositionUnknown
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.05
Grand average of hydropathy-0.365
Instability index62.00
Isoelectric point8.56
Molecular weight80728.30
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11695
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     185.91|      39|      39|     637|     675|       1
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  489-  514 (33.50/ 6.67)	SQQTSA...QSKYIRVWEGSLSGQRQGQP..........
  637-  675 (82.61/26.22)	QQQHLPQLQQQQQLPHMPQQLQQQQQQLPQLQQQQQQQL
  679-  712 (69.80/21.12)	QQQQLPQLQQQQ.LS....QLQSQQQQLPQLQQLQQQQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     304.79|      70|      73|     305|     375|       2
---------------------------------------------------------------------------
  260-  300 (59.28/21.97)	.............TG.GPPT...SLP.SV.......NGTIANRQPI.....PAGNVTPATVKV............EQVPVTSM
  305-  375 (117.98/53.82)	AFPHNSSAARATSTGQGNPSLQASSPSSVSQDiMTSNENAQDTKPIVSMLQPLRPVNPAQVNG............NILNNLSQ
  378-  450 (85.43/34.83)	QVAQNTGLASLTSAT...SNLSSSSNTGISQS.LANLQGA......VSMGQQASGMNPGNLSGaqmvqggvnmnqNVMNGLGQ
  451-  485 (42.10/13.52)	.........SVVSSGNGAMIPTPGMPQQVQ.................SGMQPLVN.NAASAN.....................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     278.92|      91|     508|      21|     126|       3
---------------------------------------------------------------------------
   21-  126 (137.38/110.11)	DTLQMDY..IEKIVRcLCGNESSGQKPSVSNVEF.ALVTYNTHGcYSGILVQR..TGWTKDPDVFLqwLSSVpfSGGGFNDVAiaeglaealMMFP......HSQSGGPNQQSADMH
  530-  631 (141.54/77.81)	ETLAANWppVMQIVR.LISQDHMNNKQYVGKADFlVFRAMNPHG.FLGQLQEKklCAVIQLPSQTL..LLSV..SDKACRLIG.........MLFPgdmvvfKPQLSSQQQQMQQQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.73|      21|      34|     196|     216|       6
---------------------------------------------------------------------------
  196-  216 (35.89/23.73)	AVYNAGKRNNRAADPPVDAKT
  233-  253 (34.84/22.80)	ALSRSGITNLPSNQSPVKVDT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11695 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AGMGQTYVQGPGRSQMVSQGQVSSQGATNIGGGNFMS
2) ALSRSGITNLPSNQSPVKVDTVSVTPVTGGPPTSLPSVNGTIANRQPIPAGNVTPATVKVEQ
3) PVTSMITGPAFPHNSSAARATSTGQGNPSLQASSPSSVSQDIMTSNENAQDTKPIVSMLQPLRP
4) SLANLQGAVSMGQQASGMNPGNLSGAQMVQG
715
233
296
406
751
294
359
436










Molecular Recognition Features






MoRF SequenceStartStop




NANANA