<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11694

Description mediator of RNA polymerase II transcription subunit 25 isoform X1
SequenceMAEKQLIVVVESTAAMGPYWDTLQMDYIEKIVRCLCGNESSGQKPSVSNVEFALVTYNTHGCYSGILVQRTGWTKDPDVFLQWLSSVPFSGGGFNDVAIAEGLAEALMMFPHSQSGGPNQQSADMHMHCILVAASNPYPLQTPVYVPQLQSLEQSESVDSEPGKQLYDAEAVAKVFPQFSISLSIICPKQLPKVKAVYNAGKRNNRAADPPVDAKTSHFLILISEGFREARGALSRSGITNLPSNQSPVKVDTVSVTPVTGGPPTSLPSVNGTIANRQPIPAGNVTPATVKVEQVPVTSMITGPAFPHNSSAARATSTGQGNPSLQASSPSSVSQDIMTSNENAQDTKPIVSMLQPLRPVNPAQVNGNILNNLSQARQVMNSAALSGGTSMGLPSMGQTPVAMHMSNMISSATTSSGPTGQNVFSSGPPVITSITSSGSLTAPAQVAQNTGLASLTSATSNLSSSSNTGISQSLANLQGAVSMGQQASGMNPGNLSGAQMVQGGVNMNQNVMNGLGQSVVSSGNGAMIPTPGMPQQVQSGMQPLVNNAASANLPLSQQTSAQSKYIRVWEGSLSGQRQGQPVFITKLEGYRSSSASETLAANWPPVMQIVRLISQDHMNNKQYVGKADFLVFRAMNPHGFLGQLQEKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDMVVFKPQLSSQQQQMQQQHQQMQSQQQHLPQLQQQQQLPHMPQQLQQQQQQLPQLQQQQQQQLSQLQQQQLPQLQQQQLSQLQSQQQQLPQLQQLQQQQMVGAGMGQTYVQGPGRSQMVSQGQVSSQGATNIGGGNFMS
Length818
PositionUnknown
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.04
Grand average of hydropathy-0.320
Instability index61.42
Isoelectric point8.56
Molecular weight87182.51
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11694
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     185.91|      39|      39|     704|     742|       1
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  556-  581 (33.50/ 7.79)	SQQTSA...QSKYIRVWEGSLSGQRQGQP..........
  704-  742 (82.61/29.72)	QQQHLPQLQQQQQLPHMPQQLQQQQQQLPQLQQQQQQQL
  746-  779 (69.80/24.00)	QQQQLPQLQQQQ.LS....QLQSQQQQLPQLQQLQQQQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     219.93|      40|      40|     232|     271|       2
---------------------------------------------------------------------------
  232-  269 (59.32/25.87)	...........GAL..SRSGITNLPS.NQ..SP..VKVDTVSVTPVTG........GPPTSLPS
  270-  308 (41.72/15.96)	VN.........GTI.aNRQPI...PAgNV..TPatVKVEQVPVTSMIT........GP..AFPH
  309-  350 (43.09/16.73)	NS.........SAAraTSTGQGN.PS.LQasSP..SSVSQDIMTSNEN........AQDTK.PI
  351-  395 (40.31/15.16)	VSmlqplrpvnPAQ..VNGNILN....NL..SQ..AR.QVMNSAALSG........GTSMGLPS
  430-  474 (35.49/12.44)	VI.........TSI..TSSGSLTAPA..Q..VA..QNTGLASLTSATSnlssssntGISQSL..
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      75.12|      15|      49|     478|     492|       3
---------------------------------------------------------------------------
  478-  492 (31.87/16.45)	QGAVSMGQQ.ASGMNP
  517-  529 (21.64/ 8.43)	QSVVSSGNG.A..MIP
  531-  543 (21.61/ 8.42)	PG...MPQQvQSGMQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.37|      28|     387|     396|     425|       4
---------------------------------------------------------------------------
  396-  425 (48.94/25.80)	MGQT.pvAMHMSNMISSATTSS.GPT...GQNVFS
  784-  818 (39.43/15.25)	MGQTyvqGPGRSQMVSQGQVSSqGATnigGGNFMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     278.92|      91|     575|      21|     126|       5
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   21-  126 (137.38/121.56)	DTLQMDY..IEKIVRcLCGNESSGQKPSVSNVEF.ALVTYNTHGcYSGILVQR..TGWTKDPDVFLqwLSSVpfSGGGFNDVAiaeglaealMMFP......HSQSGGPNQQSADMH
  597-  698 (141.54/85.93)	ETLAANWppVMQIVR.LISQDHMNNKQYVGKADFlVFRAMNPHG.FLGQLQEKklCAVIQLPSQTL..LLSV..SDKACRLIG.........MLFPgdmvvfKPQLSSQQQQMQQQH
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11694 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AGMGQTYVQGPGRSQMVSQGQVSSQGATNIGGGNFMS
2) ALSRSGITNLPSNQSPVKVDTVSVTPVTGGPPTSLPSVNGTIANRQPIPAGNVTPATVKVEQ
3) ARQVMNSAALSGGTSMGLPSMGQTPVAMHMSNMISSATTSSGPTGQNVFSSGPPVITSITSSGSLTAP
4) PVTSMITGPAFPHNSSAARATSTGQGNPSLQASSPSSVSQDIMTSNENAQDTKPIVSMLQPLRPVNPAQVNGNILNNL
782
233
376
296
818
294
443
373










Molecular Recognition Features






MoRF SequenceStartStop




NANANA