<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11673

Description cyclin-dependent kinase E-1
SequenceMGDGNRSNSNKPEWLLQYDLIGKIGEGTYGLVFLARIKSPTNRGKSIAIKKFKQSKDGDGVSPTAIREIMLLREITHENVVKLVNVHINHTDMSLYLAFDYAEHDLYEIIRHHRDKVNQSINQYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDGEEHGVVKIADFGLARIYQAPLKPLSENGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGAEVKATPNPFQLDQLDKIFKVLGHPTLEKWPSLANLPHWQQDSQHIQGHKYDNANLYSVVHLSPKSPAYDLLSKMLEYDPRRRITAAQALEHEYFKMEPQPGRNALVPCTPGEAFVNYPTRPVDTTTDFEGTTNMQQSQQVPSGAAIAGNMPGGHVSNRSVPRPMNVGMQRMHQLQAYNLTSQAGMGGGINPGGIPMQRGVPQQAHQQQQLRRKDQMGMPGYPPQQKSRRM
Length464
PositionKinase
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.08
Grand average of hydropathy-0.483
Instability index45.32
Isoelectric point9.18
Molecular weight52214.13
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11673
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     137.74|      35|      38|     361|     396|       1
---------------------------------------------------------------------------
  334-  358 (23.82/ 7.68)	................PGRNALVPCT.PGEAFVNyptRPVDT
  361-  396 (59.22/32.10)	DFeGTTNMQQSQ..QVPSGAAIAGNM.PGGHVSN...RSVPR
  399-  436 (54.71/25.96)	NV.GMQRMHQLQayNLTSQAGMGGGInPGGIPMQ...RGVPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.67|      28|      42|     156|     185|       2
---------------------------------------------------------------------------
  156-  185 (44.45/35.95)	LVMGDGEEHGVVKIADFGLarIYQA..PLKPL
  201-  230 (45.23/29.95)	LLLGAKHYTSAVDMWAVGC..IFAEllTLKPL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11673 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALVPCTPGEAFVNYPTRPVDTTTDFEGTTNMQQSQQVPSGAAIAGNMPGGHVSNRSVPRPMNVGMQRMHQLQAYNLTSQAGMGGGINPGGIPMQRGVPQQAHQQQQLRRKDQMGMPGYPPQQKSRRM
338
464










Molecular Recognition Features






MoRF SequenceStartStop




1) KSIAIKKFK
2) RKDQMGMPGYPPQQKSRRM
3) WLLQYD
45
446
14
53
464
19