<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11660

Description mediator of RNA polymerase II transcription subunit 23 isoform X1
SequenceMDQSQNQRTVASTTTSSRSFQFHPARVPILDLFNLYLGLGRNSRNKSDDPLREPPNKTQKRVHAINREVPPPNEQFIIDFEQLQTQFPDHEQLRSVTEAILISLVVQCSGHGPRSDFLLFVLRSLCGIGCINWDTFLPSLLSSVSSAELPVGQMSQAVSTVTSSSLSQSGMLPPPNTIANSSNFQSSNPASPLTSVHTIGSPAQSSIEPLSCAALSPVKSSDISSNGQQSKLRGSPSVRNNDISNSSLRQLCCKIILTGLEFSLKPVTYAEIFHHMLNWLVNWDQRQQGVDESDILKSWRSGRAVIAWLHSCLDVIWLLVDEGKCRVPFYELLRSDLQFIENIPDDEALFTLILEIHRRRDMMAMHMQMLDQHLHCPTFGTQRILNQTTPTISESAHLRLAAISYLSVLGEPLHGEETAISVQKGSLDWERAVRCIRHALRSAPSPDWWRRVLVLAPCYRLLSQGTTAGAVFSSEMICEATIDRIVELLKLTNSEINCWQDWLVFSDIFYFLTKSGCIDFVDFVDKLVSRLTEGDHHILKTNHVTWLLAQIIRIELVMNALNSDSRKVETTRKVLSFHREDRSSDPNSPQSILLDFVSSCQNLRIWSLNTSTREYLNNEQLQKGKQIDEWWRQASKGDRMMDYMNMDERSVGMFWVVTYTMAQPACETVMNWLTSAGVIDLLPATNLQPAERLVATREVSPLPMSLLSGFSLNLCLKLSYQMEDSLFSGQVVPSIAMVETYTRLLLIAPHSLFRSHFNHLVQKSPSMLSKPGVTLLLLEILNYRLLPLYRYQGKSKTLMYDVTKIISALRVKRGDHRVFRLAENLCLNLIFSLRDFFLVKREGKGPTEFTETLNRVTVITLAILIKTRGITDADHLLYLQNMLEQIMATSLHTWSEKTLRHFPSVLREALSGRQDKRSLAIQAWQQAETTVIHQCTQLLSPSADPSYVNTYINHSFPQHRQYLCAGALILMHGHAENINSGNLGRVLREFSPEEVTSNIYTMVDVMLHHMQIELQQGHLIQDLMLKACASLAFFVWTNELLPLDILLLALIDRDDDPHALRIVISLLDMPDLQQRVKLFCLTRGHPEHWLYTGVFKRVELQKALGNHLSWKDRYPVFFDDIAARLLPIIPLIIYRLIENDAMDTAERLLALYSPFLAYYPLRFTFVRDILAYFYGHLPGKLIVRILYVLDFSKIPFSESFPQQMSSSNPAMCPPLDYFTTLLLGIVNNVIPPLHNNSKSGCIGDASNSTLRTAQNKPPIVSQSGPANVSEGQKAFYQIQDPGTYTQLVLETAVIEILSLPVSASQIVQSLVQIVVNIQPTLIQSSNSLHSSSNGVGQSSVLPTSPSGGSTDSLGASRSTPSVSGVNTTNFASRSGYTSQQLSCLLIQACGLLLAQLPSDFHVQLYSETTRIIKENWWLTDMKRSLAEIDSAVGYALLDPTWAAQDNTSTAIGNVVALLHSFFSNLPQDWLEGSNVIIKQLRPVTSVAMLRIAFRIMGPLLPKLANAHALFNKTLSMLLSILVDVFGKNSQTSIAVDASEIADITDFLHHIIHYEGQGGPVQASSKPRPDVLALIGRAAESLRPDIQHLLSHLNTDVNSSVYAASHPKLVPNPT
Length1613
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.08
Grand average of hydropathy-0.041
Instability index50.22
Isoelectric point6.55
Molecular weight180749.51
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11660
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.11|      17|     102|      70|      88|       1
---------------------------------------------------------------------------
   70-   88 (28.97/25.43)	PPPNEqfIIDFEQLQTQFP
  173-  189 (33.14/21.15)	PPPNT..IANSSNFQSSNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.03|      23|     102|    1237|    1264|       2
---------------------------------------------------------------------------
  200-  222 (37.33/16.60)	GSPAQSSIEPLSCAALSP..VKSSD
 1240- 1264 (35.70/30.29)	GCIGDASNSTLRTAQNKPpiVSQSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     114.14|      39|     102|     772|     817|       4
---------------------------------------------------------------------------
  524-  551 (25.49/ 6.57)	VDKLVS..RLTEGDHHilktnHVTWLLAQI................
  772-  796 (32.25/13.72)	.....................GVTLLLLEILNYRLLPLYRYQGKSK
  802-  846 (56.40/46.11)	VTKIISalRVKRGDHR.vfrlAENLCLNLIFSLRDFFLVKREGKGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     160.44|      47|      49|     418|     464|      12
---------------------------------------------------------------------------
  418-  464 (83.53/51.18)	TAISVQKGSLDWERAVRCIRHALR.SAPSPDWWRRVLVLAPCYRLLSQ
  467-  514 (76.90/46.54)	TAGAVFSSEMICEATIDRIVELLKlTNSEINCWQDWLVFSDIFYFLTK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.99|      31|      50|     939|     969|      13
---------------------------------------------------------------------------
  939-  969 (56.25/39.35)	LSPSADPSYVNTYINHSFPQHRQYLCAGALI
  990- 1020 (54.73/38.07)	FSPEEVTSNIYTMVDVMLHHMQIELQQGHLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     394.32|     129|     783|     628|     771|      14
---------------------------------------------------------------------------
  628-  771 (207.10/188.60)	DEWW.....RQASKGDRMMDYMNMDERsvgmfWVVTyTMAQPACETVM............NWLTSAGVI..DLLPATNLqpAERLVATREVSPLPMSLLSGFSL.N..LCLKLSYQMEdsLFSGQVVPSIAMVETYtrlllIAPHSLFRSHFNHLV.QKSP.SMLSKP
 1414- 1566 (187.22/132.17)	ENWWltdmkRSLAEIDSAVGYALLDPT.....WAAQ.DNTSTAIGNVVallhsffsnlpqDWLEGSNVIikQLRPVTSV..AMLRIAFRIMGPLLPKLANAHALfNktLSMLLSILVD..VFGKNSQTSIAVDASE.....IADITDFLHHIIHYEgQGGPvQASSKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.43|      19|    1184|      24|      42|      15
---------------------------------------------------------------------------
   24-   42 (36.28/25.14)	PARVPILDLF.NLYLGLGRN
 1209- 1228 (34.15/23.15)	PAMCPPLDYFtTLLLGIVNN
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11660 with Med23 domain of Kingdom Viridiplantae
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