<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11654

Description mediator of RNA polymerase II transcription subunit 33B-like isoform X2
SequenceMSMTVVWERVIEITKWAQEKKTEAVVWSIEVSSWLKTAGVSLPSVELAHRLVSHICWENHVAGTWKYLEKAMEVRMVPPLLVLALLSTKVVPNRHPLLHPSAYSLYLHLLNKHVFSLSSHINSPNYPSLMNSIHNVLRLSQLYDYYYDDDDDHPHPGVVLVHFLFTLVWQLLEASLQDEGLLQHNSLLFVDPDLDLTMELELELDNHHHNVHVNNNNSNKHTLHAKNTATAIQFIARFLHNKVTSRILSLVQRNMPTHWGAFVNELERLAAKSLILRSLKNVSPKSFFPLNFKSKKMKLSSVLAASASAVQSHNDSSLWLPIDLILEDAMDGDHVMAASAVELLTGLVKALQAVNATAWHNAFLGLWIAALRLVQRERDPCEGPVPRLDTCLCMLLCITTLVVANVIEEEEGELIEEAERSPTNQRKDKPALGKCRGELVTSLQLLGDYEDLLNPPQPVIWVANQAAAKAIMFVSGHSGYLEYMNLNDLPTNCSGNLWHLIIEACIARHLIDTSAYFWPGYVSSPCNQPLHSIPNHLPSWSSLMKGSPLTPPMVNALVATPASSLAEIEKIFEFAINGSDEEKISAATILCGASLVRGWNVQEHVVFFIIKLLSPPVPPKYSGTENHLISYAPFLNVLLVGISPVDSVQIFSLHGAVPLLAAALMPICEAFGSCVPSVSWTSATGDKLSCHAVFSNAFVLLLRLWRFNHPPVEHVMGGAATPALGSQLGPEYLLLVRNCMLASFGKSPRDRIRSRRFSKMISFSSEPLFMDSFPKLNTWYQQHQECLASTRCALVPGGPILQIVDALLSMTCRKINRSAQSLTSTTSGSSNSSGSSLDDALMKLKVPAWDILEAAPFVLDAALTACAHGRLSPRELATGLKDIADFLPATLATIVSYLSAEVTRGVWKPAFMNGTDWPSPAANLSIVEQQIKKILAATGVNVPSLAIDGNAPATLPLPLAAFLSLTITYKLDKSSERFLVLIGPSLINLSSGCPWPCMPIVGSLWAQKVKRWSDFFVFSASGTVFHHSRDAVVQLLKSCFTSTLGLGSACIYNNGGVGALLGHGFGSHFCGGISPVAPGILYLRVYRSIRDAMFLTEEIVSLLMLSVRDIASGGLPKGEAHKLKKAKYGMRYGQVSLAASMTRVKHAALLGASFLWISGGSSLVQSLITETLPSWFLSAQGLEQEVGESGVVVAILRGYALAYFAVLSGTFAWGIDSLSAASKRRPKVLGIHLEFLANALDGKISLRCDCATWRAYVSGFMSLMVSCTPLWIEELDASILKRVSKGLRQLNEDDLALHLLEIRGTSLMGEVAEMISQNGF
Length1320
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.08
Grand average of hydropathy0.192
Instability index45.26
Isoelectric point6.78
Molecular weight144508.80
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11654
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     199.89|      50|      52|     757|     808|       1
---------------------------------------------------------------------------
  703-  752 (48.16/19.54)	RLWRFNHPPVehVMGgaATPALGS..QLGPEYLLLVRnCMLASFGksPRDR....I.....
  759-  808 (89.00/49.84)	KMISFSSEPL..FMD..SFPKLNTWYQQHQECLASTR.CALVPGG..PILQ....IVDALL
  813-  863 (62.73/28.44)	RKINRSAQSL..TST..TSGSSNSSGSSLDDALMKLK....VPAW..DILEaapfVLDAAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      62.57|      11|      17|       6|      16|       2
---------------------------------------------------------------------------
    6-   16 (22.35/13.53)	VWERVIEITKW
   26-   34 (18.09/ 9.45)	VWS..IEVSSW
   56-   65 (22.13/13.32)	CWENHVAGT.W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     193.50|      54|      55|    1166|    1220|       3
---------------------------------------------------------------------------
 1148- 1204 (73.20/52.50)	ALL.GASFLWisGGSSL...vqSLI.TETLPS......WFLsAQGLEQEVGESGVVVAIL..RGYALAYF
 1205- 1261 (75.05/49.28)	AVL.SGTFAW..GIDSLSA......aSKRRPKvlgihlEFL.ANALDGKISLR.CDCATW..RAYVSGFM
 1262- 1307 (45.25/26.29)	SLMvSCTPLW...IEELDAsilKRV.................SKGLRQ.LNEDDLALHLLeiRGTSL...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.94|      27|      48|     304|     332|       4
---------------------------------------------------------------------------
  304-  332 (42.70/35.94)	AASASAVqsHND.SSLWL.PIDLIL..EDAMDG
  353-  383 (37.23/23.92)	AVNATAW..HNAfLGLWIaALRLVQreRDPCEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.38|      19|      55|      95|     117|       5
---------------------------------------------------------------------------
   95-  117 (26.28/26.64)	HPllHPSAysLYLHLLNKHVFSL
  153-  171 (36.09/20.96)	HP..HPGV..VLVHFLFTLVWQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.40|      35|      49|     881|     915|       6
---------------------------------------------------------------------------
  881-  915 (60.04/36.70)	KDIADFLPATLATIVSYL...SAEVTRGVWKPAFMNGT
  929-  966 (51.37/30.25)	QQIKKILAATGVNVPSLAidgNAPATLPLPLAAFLSLT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11654 with Med33 domain of Kingdom Viridiplantae
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