<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11649

Description U-box domain-containing protein 33 isoform X1
SequenceMAVVNHVGGEIEEEPDQGVVDEAIYVAVSKDVKESKSNLIWAIQNSGGKKICILYVHVPATMIPLMGAKFPASSFKDQEVRAYRDIERQNMHKTLDEYLRICHRMGVRAEKLHIETDNIEKGILELISQQGIRKLIMGAASDKCYSRRMMDLKSKKAIYVCEQAPASCYIQFICKGHLIHTRDRSLDERNVEVASPLVQQVPNSVRSLRSQSITLGQNHRTDSINSVQELFRRAKSASDEQRPSNVDVPSPDDTARFSTPRNMRGTEVSSDESDRLSKTSPSGLSTCSDSAIEPALTPNSVAESSEIALELSLSHLVIEDLHHLSPPSVLQDGGVNDTLYDQLEQAMSEAHNATRNAYQETFRRGKAEKEAIEAIRKAKASESLYTEELNLRKMAEEELKKEKEELENITSQRDKVQEELQLALDLKSSLESQLASSEVMVQELEQKIISAVELLQSYKNEREELQMQRDNALREAEELRKKQGDDSSSHVPQLFSEFSFSEIEEATRNFDPSLKIGEGGYGNIYQGILRHTEVAIKILHANSMQGPLEFQQEVDVLSKLRHPNLITLIGACPESWSLVYEYLPNGSLEDRLVCKDNTPPLSWQTRIRVAAELCSALIFLHSSKPHSIVHGDLKPSNIILDANLVSKLSDFGICRILSNYENSSNNSTQFWKTDPKGTFVYMDPEFLASGELTPKSDVYSFGIILLRLLTGRPALGITKEVKYAIDTGKLTSLLDPLAGDWPFVQAEQLARLALRCCEMNRKSRPDLHSDVWRILDSMRASSGGTNSFGLSSEGPHQPPSYFICPIFQEVMRDPHVAADGFTYEAEAIRGWLDSGHDTSPMTNSTLAHQSLVPNRALRSAIQDWLQSH
Length868
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.06
Grand average of hydropathy-0.456
Instability index53.24
Isoelectric point5.45
Molecular weight97222.60
Publications
PubMed=26259924

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11649
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.81|      45|      49|     612|     657|       1
---------------------------------------------------------------------------
  565-  615 (56.51/34.94)	.LITLIGACPEswSLVYEYL.P.NGSLEDRLVCKDNT...PPLswqTRIRvaaELCS
  616-  664 (69.73/49.40)	ALIFLHSSKPH..SIVHGDLKPsNIILDANLVSKLSD...FGI...CRILsnyENSS
  678-  709 (31.57/16.20)	TFVYM...DPE..FLASGELTP...........K.SDvysFGI.ilLRLL.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     103.64|      34|      53|     380|     414|       2
---------------------------------------------------------------------------
  355-  378 (20.15/ 9.11)	............RNAYQETF........................RRGKAEKEAIEAiRKA
  380-  414 (49.49/40.71)	ASESLyTEELNLRKMAEEEL........................KKEKEELENITS.QRD
  416-  470 (34.00/21.37)	VQEEL.QLALDLKSSLESQLassevmvqeleqkiisavellqsyKNEREELQ...M.QRD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.34|      16|      19|     240|     258|       3
---------------------------------------------------------------------------
  240-  258 (23.86/20.72)	EQRPSNVdvpSPDDTARFS
  262-  277 (27.48/14.61)	NMRGTEV...SSDESDRLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.54|      18|      19|     523|     540|       4
---------------------------------------------------------------------------
  523-  540 (31.92/18.92)	NIYQGILR.HTEVAI..KILH
  542-  562 (23.62/12.38)	NSMQGPLEfQQEVDVlsKLRH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11649 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HHLSPPSVLQDGGVNDTLYDQLEQAMSEAHNATRNAYQETFR
2) INSVQELFRRAKSASDEQRPSNVDVPSPDDTARFSTPRNMRGTEVSSDESDRLSKTSPSGLSTCSDSAIEPALTPNSVAES
322
224
363
304










Molecular Recognition Features






MoRF SequenceStartStop




NANANA