<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11634

Description mediator of RNA polymerase II transcription subunit 33A isoform X3
SequenceMLYQEMELDGHDNYNDKNTEQNEKLHSANTLMAVEIIGRFLQDRVTSRILCLARRNLPAHWLSFVQRLQLLGANSLALRKSKTLSPEALLHLTSDTCMVLSQESKTNSQQKFHKVMAFEYLSSSASLCHGASHSALWIPLDLVLEDAMDGYQVSATSAVEEISGLIKTLRAINGTSWHDTFLGLWFASLRLVQRERDPIEGPMPHLDTRLCMLLCITPLVVANLIEEEEPIPIDEKDSVTDHWKEKRVPGKCRNDLVSSLQVLGDYQSLLTPPQSVITAANQAAAKAMLFISGITVGSAYFDCLAMTEMPVDCSGNMRHLIVEACIARNLLDTSAYLWPGYGNGHINQRPQCMPAPVPGWSSFMKGEPLTSVLVNALVSSPATSLAELEKIFEFAIAGSEDEKISAATILCGASLIRGWNIQEHTVHFILRLLSPRVPVENTEGNNYLINYAPILNALFVGIASIDCIQVFSLHGLVPQLACSLMPICEVFGSCVPNISWTLTSGEEISAHAVFSNVFILLLKLWRFNRPPLDHGIGDVPTVGSQLTPEYLLLVRNSHLMSAGNNCKDRNRRRLSEIASLSSPNSVFVDSFPKLKVWYRQHQACIASTLSGLVHGTPFHQIVEGLLNMMFRKINRGNQTTITVPSGSSSSSGPVNEDASIGPMLPAWDILEAIPFVVDAALTACAHGRLSPRELATGLKDLADFLPASLATIISYFSAEVTRGVWKPAFMNGTDWPSPAANLLNVEEQIKKILAETGVVVPSLAPVVAISTGDSSPATLPLPLAAFTSLTITYKVDRSSERFLHLAGQTLEGLAAGCPWPCMPIVASLWTQKAKRWSDFLIFSASRTVFLHNSDAVVQLVKSCFTATLGMSSSPISCSGGVGALLGHGFKSNLSGGICPVAPGILYLRAYRSIRDIVFLTEEIVSILMQSVREIVCGGLPKQRLKKSKATKDSIKYGQVSLAASMTRVKLAAALGASLVWISGGLTLVQLLIKETLPSWFISVHRSDQEEKSNGMVAMLGGYALAYFAVLSGAFAWGVDSSSSASKRRPKVLGTHMEFLASALDGNISLGCDPATWRAYVSGFVSLMVSCTPNWVLEVDVHVLKRLSNGLRQLNEEELALALLGAGGVGTMGAAAELIIDTEM
Length1143
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.07
Grand average of hydropathy0.175
Instability index46.18
Isoelectric point6.29
Molecular weight124054.95
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11634
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     162.28|      55|     116|     615|     678|       1
---------------------------------------------------------------------------
  615-  678 (82.87/72.80)	GTPFHQIVEGLLNM..MFRKInrGNQTTITVPsgsssSSGPVNEdASIG.......PM.LPAWDILeAIPFVVD
  732-  796 (79.41/46.24)	GTDWPSPAANLLNVeeQIKKI..LAETGVVVP.....SLAPVVA.ISTGdsspatlPLpLAAFTSL.TITYKVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     139.89|      43|     116|     167|     214|       2
---------------------------------------------------------------------------
  167-  214 (67.78/57.21)	KTLRAINGTSWHDTFlglwFASLRLVQRERDpIEGPMPHLDTRLCM...LL
  286-  331 (72.11/44.66)	KAMLFISGITVGSAY....FDCLAMTEMPVD.CSGNMRHLIVEACIarnLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.65|      33|     281|     104|     137|       3
---------------------------------------------------------------------------
  104-  137 (55.30/45.27)	SKTNSQQKFHKVMAF.......EYLSSSASLChGASHSALW
  380-  419 (50.35/35.12)	SPATSLAELEKIFEFaiagsedEKISAATILC.GASLIRGW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.98|      25|     712|     343|     374|       6
---------------------------------------------------------------------------
  343-  374 (34.43/35.85)	NGHINQrpQCMPAPvpgWSSFMKGepLTSVLV
 1064- 1088 (47.55/24.66)	DGNISL..GCDPAT...WRAYVSG..FVSLMV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.06|      12|     710|      85|      96|       7
---------------------------------------------------------------------------
   85-   96 (21.35/11.65)	SPEALLHLTSDT
  798-  809 (21.71/11.96)	SSERFLHLAGQT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.07|      38|     281|     243|     282|       8
---------------------------------------------------------------------------
  243-  282 (59.15/40.97)	WKEKRVP...GKCRNDLVSSlQVLGDYQsLLTPPQSVITAANQ
  525-  565 (64.92/36.81)	WRFNRPPldhGIGDVPTVGS.QLTPEYL.LLVRNSHLMSAGNN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11634 with Med33 domain of Kingdom Viridiplantae
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