<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11605
Description |
Mediator of RNA polymerase II transcription subunit 13 |
Sequence | MEIDSGKWSASGFVLLDCPQSMKIESNNASLLGSISDYFLSLSNGWDLACYLKSLSKALKALKLGQFLSTNQKEGISGPCMVIYVVCPFPEPTAVLKTVIESSIAVGSIILPSDRERRSVLHSQVGKALSSSAAADEASISNIPVVSGFSVPKLVLQIVTVDAIFRVTSPPFNELVVLKETAFTIYNKARRISRGSVNDVLSSSFSNRSHSVLTPMTSIPGMWNSRISGSSLPREGEIDSSLRAGAWDNSWQATRTGGLSCDPNRNGDIYYQDEVRYMFEPLFILAESGSVEHGVSPTGFGNLTSETSKTVSDESSGGFMQNANSTGSIDPGSGSQFDTSEPDALSSGSHKTPSLHCCYGWTEDWRWLVCTWTDARGELLDCNIFPFGGISSRQDTKGLQCLFVQVLQQGCQILQTCAFDTGVIKPRDFVITRIGNFYELEYLEWQKAIYSVGGSEVKKWPLQLRRSVPDGMPASTNGTSLQQQEMSLIQERTLPSSPSPLYSPHTKTGFMKGGLGQPAARKQLMSGHTIVDNSRGLLQWVQSISFVSVSVDHSLHLVLQADGISPGTHGVGGMGQSSYIEGFTPVKSLGSASASYMLIPSPSMRFLPPTPLQLPICLTAESPPLAHLLHSKGSAIPLSTGFVVSKAVPSMRRDYRNYTKEEWPSILSVSLIDYYGGNNVGQMRGMAKQAGSSVSSEARDFEIDNHLILESVAAELHALSWMTISPGYLERRSALPFHCDMVLRLRRLLHFAEKELSRQPDKPQV |
Length | 765 |
Position | Kinase |
Organism | Corchorus olitorius |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
rosids> malvids> Malvales> Malvaceae> Grewioideae> Apeibeae> Corchorus.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.145 |
Instability index | 53.32 |
Isoelectric point | 6.37 |
Molecular weight | 83290.61 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364134
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP11605
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 212.42| 57| 58| 461| 517| 1
---------------------------------------------------------------------------
461- 512 (84.78/47.69) .......................................PLQLR.....RSVP.........DGMPASTNGTSLQQ..QEMSLIQERTLPSSPSPLYSPHTKTGFMK
513- 570 (84.56/47.55) GGLGQ..................................P.AAR.....KQLM.........SGHTIVDNSRGLLQwvQSISFVSVSVDHSLHLVLQADGISPGTHG
572- 663 (43.08/20.62) GGMGQssyiegftpvkslgsasasymlipspsmrflpptPLQLPicltaESPPlahllhskgSAIPLST.G...........FVVSKAVPSMRRD.YRNYTKEEW..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 61.92| 17| 58| 83| 99| 2
---------------------------------------------------------------------------
83- 99 (32.39/18.69) IYVVCPFPEPTAVLKTV
143- 159 (29.53/16.44) IPVVSGFSVPKLVLQIV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 128.92| 40| 58| 257| 314| 3
---------------------------------------------------------------------------
257- 301 (63.52/81.60) GGLSCDPNRNGDIYYQDEVRY.MFEPLFIlaESGSveHGvSPT...GFG
317- 360 (65.40/38.57) GGFMQNANSTGSIDPGSGSQFdTSEPDAL..SSGS..HK.TPSlhcCYG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 61.03| 20| 463| 221| 242| 5
---------------------------------------------------------------------------
221- 242 (31.36/22.33) GMwnSRISGSSL...PREGEIDSSL
685- 707 (29.67/13.94) GM..AKQAGSSVsseARDFEIDNHL
---------------------------------------------------------------------------
|