<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11552

Description "Mediator complex, subunit Med12"
SequenceMQRYHPANCTSAVNNSAIGGASARDTSRADSSTLPPNFSLNSRRQSQLAPYKLKCDKESLNSRLGPPDFHPQSQNCPEETLTRENVQQGYKETIDGLEDSKEISLTQIQAFTKPVVLKCRDAIRKCLRAINESRAQKRKAGQVYGIPLSGSLLSKPGVFPEQRPCNEDFRKKWIEGLSQQHKRLRSLADQVPHGYRKRTLIEVLIRNNVPLLRATWFIKVTYLNQVRPGSAISSGAPDKTQLSRTELWTKDVIDYLQYLLDEFSSRNNSHSTQHGRDRLPQMLYTGSLQHRNDSALTIVDGEEPSLHFKWWYVVRLLQWHHAEGLVLPSLIIDWVLSQLQEKELLEILQLLLPIIYGVLETIILCQTYVRNLVGIAIRFIREPSPGGSDLVDNSRRAYTISALVEMLRYLIQAVPDTFVALDCFPLPACVVSHALNDGGFLSKSSDDAGKTKNTLADAYVLKGRGFDSQYQSLSFDHVVSTIQKRADYLAKGASAEYPSQSVAKAVQTLDKALLQGDLVEAYKHIFEDLCDGVVGEGWVAEVSPCLRSSLKWIRTVNVSLICSVFFLCEWATCDFRDFRTAPPRDVKFTGRKDISQIYLAIQLLKLKMRELQNPQHKNGRASKSTAKYSSQQNNYSRRTLLGNQYEAKSNARGMDGRSSNSSDLFDSPGPLHDIIVCWIDQHEGHKGEGGKRLQLFVLELIRSGIFYPLAYVRQLLVSGIIDTNGPAGDLDRRKRHHRILKQLPGQFMCDALEEARIAEASELLEAVNVYSNERRLVLKGLLFDQCNNGNYANVSSKKQKYHATSAKDAASQALGDQWKIGQSSKTFRRDVDLEELKASISALLQFPSSSSTSADSGVDESQGSAKRSVGSIGNKMDSFEGTPGCEDCKRVKRQKLSEEKSSSLQVPSPIPSDDEDTWWVRKGPKNLEPFKADPPLKSTKQVSRGRQKTVRKTQSLAQLAAARIEGSQGASTSHVCDNKISCPHHRTDAETLKPVDGIRTTPSGDIVSIGKGLKQLRFVEKRTVTVWLISVVRQLVEEYEKSVAKVGQYGRPFVAADEKSPLRWKLGEDELSTILYLMDVSCDSALAVKFLLWLLPKVISNPSPTIHGGRNIIMVPRNVENHACEVGEAYLLSSLRRYENILIAADLIPEALSATMHRAAAVLATNGRITGSGALVFARYLLKRYGNITSVIDWEKNFKPTCDKRLLSELESGRTVDGEFGFPLGVPAGIEDPDDYYRQKIASGRVSRVGLNMRDMVQRHIDDVLHYFLGKERKLFAGNAPKGLAMEKGDDGYQVAQQIIVGLLECLRQTGGAAQEGDPGLLSSAISAIVSNVGPAIAKIPDLTVGGNYSNYQQPVNSLNIAKRILRIHIICLSLLKEALGERQSRAFEVALGTEASSALAVAFAPAKSSRGQFQLPPDGPDSNANIPGDNMSSAKVTLGRTTKMAAAVSALFIGAVIHGVISLERMVSVLRLKEGLDVVQFVRNTKTSSNGNARSAGPFKDNSVEVNVHWFRLFVGNCRTVCDGLVLELLGEQSVVALSRMQRLLPIDLVFPPAYAIFAFVIWKPFILNSNIATREDIHQLYLSLTMAIGDAIKHMPFRDACMRDSRTFYDIVAADTTDTEFAALLEMNGLDMHLKSMAFVPLRARLFLNAIIDCEMPYSASQQDDGTRVSGHSESKALRESEPKLSDKLVRALDTLQPAKFHWQWVELRLLLNEQALIDKMENHDMPLVDAIRSSSPSSERASPSENEKFLIEIILTRLLVRPDAASLFSEVIHLFGRSLEDSMLMQAKWFLGGQDVLLGRKTVRQKLINIAESRSLSTKTQFWKPWGWSHSGVDPITNRGDKKKYEVTSLEEGEVIEDGMESKRHVKGSSKVDLGSSISRLHVTEKAFVELVLPCIDQSSDDSRNTFASDLIKQFNTIEQQMSSVTRGVSKQTGSASSGIEGSVSKGNNRKGMRGGSPGMSRRTVVPAESAPPSPAALQASMSLRLQIIVRLLPIICADGEPSARNMRHMLASVILRLLGSRVVHEDVDLSLNLLNSKRDMEMMSSVASSEMSGDSLFDRLLLVLHGLLSSCQPNWLRSKTATKATSEIAKNSSGFDREAVESLQNELDSMQLPEMIRWRIQAAMPILFPSFRNLISCHTPSVPIGALSSLQPSIFVPGSYPGTLSAPQRQGPSTRTSNNTQGKSKSMPVVQEYDMEIDPWTLLEDGAGSGPSTSSTAVIGSSDHANLRASSWLKGAVRVRRTDLTYIGAVDDDS
Length2258
PositionKinase
OrganismCorchorus capsularis (Jute)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Grewioideae> Apeibeae> Corchorus.
Aromaticity0.07
Grand average of hydropathy-0.290
Instability index50.57
Isoelectric point8.79
Molecular weight249732.96
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11552
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.47|      48|     449|    1534|    1586|       1
---------------------------------------------------------------------------
 1534- 1586 (67.81/62.37)	QSVVALsRMQ...RLLPIDLV..FPPAYA...IFAFVIWKpfILNSNIaTREDIhQLYLSL
 1982- 2037 (67.67/41.47)	QASMSL.RLQiivRLLPIICAdgEPSARNmrhMLASVILR..LLGSRV.VHEDV.DLSLNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     280.02|      91|     364|     262|     361|       2
---------------------------------------------------------------------------
  262-  361 (135.06/136.24)	EFSSRNNSHS..TQHGRDRLPQMLYTGsLQHRNDSALTIVDGEEPsLH...FKWwyvVRLLQWHHAE.GLVLPSLIIDWVLSQLqEKELLEILQLLlpiIYGVLET
  627-  723 (144.96/109.52)	KYSSQQNNYSrrTLLGNQYEAKSNARG.MDGRSSNSSDLFDSPGP.LHdiiVCW...IDQHEGHKGEgGKRLQLFVLELIRSGI.FYPLAYVRQLL...VSGIIDT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     171.68|      53|     193|    1218|    1273|       3
---------------------------------------------------------------------------
 1218- 1273 (90.28/71.53)	GEFGFPLGVP.AGIEDP.DDYYRQKIASGRVSRVGLNMRDMvqrHIDDVLHYFLGKER
 1412- 1466 (81.40/56.16)	GQFQLPPDGPdSNANIPgDNMSSAKVTLGRTTKMAAAVSAL...FIGAVIHGVISLER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     355.28|     116|     976|     730|     967|       4
---------------------------------------------------------------------------
  839-  967 (180.04/324.83)	SISALLQFPSSSSTSaDSGVD..ESQGSAKR.SVGS......IGNKMDS...FEGTPGCEDCKRVKRQKLSEEKSSSLQVPS.PIPSDDEDTWWVRKGPKNLEPFKadpplKSTKQVSRGRQKtvrKTQSlaqlAAARIEGS
 1818- 1946 (175.24/91.28)	SLSTKTQFWKPWGWS.HSGVDpiTNRGDKKKyEVTSleegevIEDGMESkrhVKGSSKVDLGSSISRLHVTEKAFVELVLPCiDQSSDDSRNTFASDLIKQFNTIE.....QQMSSVTRGVSK...QTGS....ASSGIEGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     318.24|     105|    1711|     365|     515|       5
---------------------------------------------------------------------------
  403-  515 (150.15/167.88)	LVEMLRYLIQ.AVPDTFVA....LDCFpLPACVVShALNDggfLSKSSDDAGKTKNTLAdAYVLKG....RGFDSQYQSLSFDhVVSTIQKRAD...YLAKGASAeYPSQSVAKAVQTLDKALLQ
 2116- 2232 (168.09/89.80)	LPEMIRWRIQaAMPILFPSfrnlISCH.TPSVPIG.ALSS...LQPSIFVPGSYPGTLS.APQRQGpstrTSNNTQGKSKSMP.VVQEYDMEIDpwtLLEDGAGS.GPSTSSTAVIGSSDHANLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.38|      42|     189|     786|     831|       6
---------------------------------------------------------------------------
  786-  831 (68.17/63.05)	CNNgnyaNVSSKKQKYHATSAK..DAA.SQALGDQWKIGQSSKTFR....RDV
  976- 1024 (60.21/43.75)	CDN....KISCPHHRTDAETLKpvDGIrTTPSGDIVSIGKGLKQLRfvekRTV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11552 with Med12 domain of Kingdom Viridiplantae
Unable to open file!