<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11508

Description Ergosterol biosynthesis ERG4/ERG24
SequenceMKEEFEIEITFNEILGGGPTADGGGGHGLLGIQRVGQFLDQLSQAGGLGVRWGDPVRRSGEERKPIRCSTAYDDPADSVFELPEERIGGRVGFGLDMLDFLCGGIQSGLNGSSRVVGGVGAAEKLNQAVQQQLNLESLKTRAISLFKAITRILEDFDAYSRTNTTPKWQDILGQYSMVNLELFNIVDEIKKVSKAFVVHPKNVNAENAPILPVMLSSKLLPEMETEDNLKREQLLQGMQNLPIPSQIEKLKTRIDMIGAACESAEKVLADTRKAYCFGSRQGPAILPTLDKGQAAKIQEQENMLRNAVNFGEGLRLPADQKQITPSLPLHLADIMPAADGVHSFADPSGIYMKSTPPLSSNSIGSQASLLQASGAQLIGRSAASPSAATSATSFDNTSNSPLPYVNSPRSGTTMMNTPSPQQQTQQHQQQQQQQQQQQQQQQRQKMMQLPQHQQQLLAQQQYRQSTMQGLGQNQLPLHDLQGQTQQKFQSLHGQMQYSQSLGHQQFQGRQLPPGHVQHGIGQSQLNQGNQLSRQLSQFSSPANTALFNAAQATPSTQMIPNMSATMSSQSLLPRMQFGLSGSNPQRSHASQLLNDQMFNMGSSASGMMQMQPQQQQQQQQGAFGNMPTAQNLQSNMIWNDVLGSSRRVTYCIKQYELYGKVADSMLVNTILMLLDSIFIGGLVWVPSVHTSPGMYLVNHPVNLGTQLALYIIVAGILCIYINYDCDRQRQEFRRTNGKCKVWGKAPSKIEATYTTSGETKTNLLLTSGWRVM
Length772
PositionHead
OrganismCorchorus olitorius
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Grewioideae> Apeibeae> Corchorus.
Aromaticity0.06
Grand average of hydropathy-0.458
Instability index55.54
Isoelectric point8.46
Molecular weight84833.16
Publications

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	GO:0016628	IEA:InterPro
GO - Biological Process
sterol biosynthetic process	GO:0016126	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP11508
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     167.27|      23|      23|     431|     453|       1
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  431-  453 (47.53/20.41)	QQQQQQQQQ............QQQRQKMMQ.LPQ.HQ
  454-  474 (27.51/ 8.64)	QQ...LLAQ............QQYRQSTMQgLGQ.NQ
  482-  516 (23.56/ 6.31)	GQTQQKFQSlhgqmqysqslgHQQFQGR.Q.LPPgHV
  585-  607 (28.50/ 9.22)	QRSHASQLL............NDQMFNMGS.SAS.GM
  608-  630 (40.18/16.08)	MQMQPQQQQ............QQQQGAFGN.MPT.AQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.89|      28|      72|     209|     246|       3
---------------------------------------------------------------------------
  209-  237 (42.65/24.11)	P.ILPvMLSSKLLPEMETEDNLKREQLLQG
  283-  311 (42.24/24.29)	PaILP.TLDKGQAAKIQEQENMLRNAVNFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.40|      14|      55|      34|      53|       4
---------------------------------------------------------------------------
   34-   47 (25.90/ 7.44)	RVGQFLDQLSQAGG
   90-  103 (26.50/ 8.41)	RVGFGLDMLDFLCG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.08|      11|      14|     390|     403|       5
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  390-  403 (16.29/18.42)	SATSFDNTsnsPLP
  410-  420 (22.79/14.55)	SGTTMMNT...PSP
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP11508 with Med8 domain of Kingdom Viridiplantae

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