Description | Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MDTIIDARFERVEKALACLIESVSKYHPHARQALDLHEADNDLARGLEEVQTHQNNHIRLQQLRATTASLDNQIKETLQNLAVTRKDITTTQITPQPDGPNYPVKYDELLNYARRISKTTLPPAAVINNFPTSSGTPPPDPNTSITTNPNTPAANGLQSQPVSAAPTPSQTQTPDPTGGPNGGSAQDLSATHQANTVTSLPDGLRNHLDPHFNASFIPWPNEFQIRSGAMAVFQDLQDKGIDPRGYDPQQIAEAKRKEEEERKAREEQDRLETERKNREYQEKMEKIRREQQEAYRRDSMAVGGAGASSAGKSKQFQFTSIMDDDDDED |
Length | 329 |
Position | Middle |
Organism | Colletotrichum chlorophyti |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Glomerellales> Glomerellaceae> Colletotrichum. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.986 |
Instability index | 49.99 |
Isoelectric point | 5.15 |
Molecular weight | 36619.78 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP11461 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 186.43| 61| 77| 76| 142| 1 --------------------------------------------------------------------------- 98- 172 (89.21/50.73) DGPNYPVKYDeLLNYARRISKTTLpPAAVINNF.PTSSGTPPPDPNtsittnpntpaaNGLQSQPVSAAPTPSQTQ 178- 251 (97.21/40.50) GGPNGGSAQD.LSATHQANTVTSL.PDGLRNHLdPHFNASFIPWPNefqirsgamavfQDLQDKGIDPRGYDPQQI --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 40.32| 12| 26| 258| 269| 2 --------------------------------------------------------------------------- 258- 269 (19.71/11.24) EEEERKAREEQD 281- 292 (20.61/12.02) QEKMEKIRREQQ --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 67.76| 22| 26| 13| 34| 3 --------------------------------------------------------------------------- 13- 34 (38.10/30.85) EKALACLIESVSKYHP.HAR.QAL 40- 63 (29.67/22.37) DNDLARGLEEVQTHQNnHIRlQQL --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) AGKSKQFQFTSIMDDD 2) EAYRRDSMAVG 3) YPVKYDELLNYARRI | 310 293 102 | 325 303 116 |
© 2021 Shailesh Lab
Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab