<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11426

Description Uncharacterized protein
SequenceMNPAQFSNPGGGMSGLVKPGMSQQQSQQQRNENAQLIMSSVAQELQMQPRLGGWKDEVPIKVRAMNVYQMITSLRLIQPRIDLKQAGNAAIAFETGAFKKAAERSDYEKDCNEKLLHIKDTRQRQAAVAIQSGMMPQGGPAMQNQLQGGFPPQMNPNMQASPVAPGQSQMAMGMNGPNQQAAMQQRQQQQQQQAMLQQQQQQQHHQQQQQQQQQQQQQQQQQQQQQQQQQRAQQRPPNGLLLPDDVTGLQNPEAEHVIRLADQMMHKTSPADVEKIKLNLANMNPEQRDYLQRQGIEPITYFFRTQAVTQLRRFRNRTGMNMGRPANAANANADAMLTGDPMMNQQAMFQNMMNLQRSNSTFSGNPAQGQDPNAFFGNVENIQGQQADGLRSQEAGQLVVPASSSQMNQAPFNNQQNLFPQQSGQNGQGNGAMNGMGMNPQMFSQQQMQQGLPNGAQQFQAQQAQAQARAHAAAQKAQLAMSGQVNPQAQAQFSQQSPVMPMLNQGMPPGQISPVPMAAQVRPPSRPANMGQHPGGMQAAQPTMQNRPQIPPNLPGPIQEQLSGLTNEQLHSFLQTQRRAHANNLTRANLQQQQQQQQQQPAPQSQPQQQQQQQQGSLPQDVQNPAMFNGQMVNNPRMRNSMSMPQGMNMAAGLLQNQQQLTPQQRAVRQQRQTEMMKLNALRKQNNGHEMTVDQQKEMDRVPFPPSLVANNPHVPQHIKTWAQIKHWASTNPVTTTGVDFNRLLTLQKLHFAQILATKIAQQQNQQNQQNQQNQQNQAQIQQAYQGPQNGMQIPQNHPHPGMNIAMRPITNEDVQSARQKLGSNSSNYTDDQIRELLRNKQRQMLEQAVQQRALAMGRAVPQPPGVVPQKQTQVPPVPVAQQPPQVTGDLQPPNPRPQQAAPAPKGGKAPTVNQRSKKRPNQDDIVVEMPVMNTTPQQPQATPIAKNSVPQKPVPNQALSQEGLAAMTPEQRLHVEQTMRLQQQALFRGQYFNRAVAESNWKNNLPPKLLDIYNEISKAAPAPNIVTVSPEQKAIMTQQLQDSLEVLARLDILVLHGFQKAANQERNIRNLLAMRIQLMRQFKNTPEWIINDHFTITPDYLTGAIIFVRKLFQMTLVRITNERQSALNRANTPAAQSEQPTQTTPLNANNLKQLQFQQQQHEEALQRARRASSQSAPVPPAPFGAPSPQGVPAYGSGGLAPEKLKLPPPKKRKQSQTGVSSSPVPASAPLIADASYKKTVADAKSAAAPLVGTFKCGIVECQFHFQGFPTQAALDKHVEESHKPEVVEVIDDPFQFYIDSLDIGLGLTADNQGANQVVTTSAGPTGLMASPVKPGLATPASSTATPMLRAPSQVVAKSASPATSAQQLTPQQGKAKKPGSKPGALDLPSEPALPWANSHMTPQELADTFDPLFDDLDDGNGLNMFSDEAFNNNAFLGADPTEDTPDSNDLALAIQTPQDDPINWSEWAEYDEESARATAEWMNIPLELQDNSGDGIPGVRVDFDRLEREQREEKELALRGGRGNLVISTVR
Length1532
PositionTail
OrganismPenicillium subrubescens
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Penicillium.
Aromaticity0.04
Grand average of hydropathy-0.812
Instability index59.46
Isoelectric point9.32
Molecular weight169236.35
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11426
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     128.79|      30|      31|     497|     527|       2
---------------------------------------------------------------------------
  438-  463 (44.60/ 8.18)	MNPQMFSQQQMQQGLPN....GAQQFQAQQ
  605-  631 (42.55/ 7.45)	SQPQQ..QQQQQQG.SLPQDVQNPAMFNGQ
  755-  783 (41.64/ 7.13)	ILATKIAQQQNQQNQQNQQNQQNQAQI.QQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     168.23|      24|      25|     504|     527|       4
---------------------------------------------------------------------------
  148-  166 (31.74/ 7.25)	GGFPP.QMNP.NMQASPVA...P.G
  505-  529 (41.83/11.96)	QGMPPGQISPVPMAAQVRPPSRPaN
  530-  548 (32.11/ 7.42)	MGQHPGGMQ....AAQPTMQNRP..
  900-  922 (30.07/ 6.47)	QAAPAPKGGKAPTVNQ.RSKKRP.N
 1175- 1194 (32.47/ 7.59)	QSAPVP...PAPFGA.PSPQGVP.A
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     752.63|     152|     375|     221|     373|       5
---------------------------------------------------------------------------
   23-  220 (116.75/32.33)	QQQSQQQRNENAQ.......................................LIMS.SVA....QE....LQMQPRLGgwkDEVPI..............................KVRAMNVY....QMITSLRLIQP...R........IDL...K...QAGNAAIafeTGAFKKAAeRSDYEKDCNEKLLHI.....kdTR.................QRQAAVAI...QSGMMPqGG.....PAMQ.......................NQlqggfppqmnpnmqaspvapgqsqmAMGMN.............gpnqqaamqqrqqqqqqqamlqqqqqqqhhqqqqqqQQ..QQQQ.QQQ
  221-  373 (257.50/82.91)	QQQQQQQQQQRAQQ................................RP.PNGLLLPDDVTGLqNPE....AEHVIRLA...DQMMH..............................KTSPADVE....KIKLNLANMNPEQ.R........DYL...Q...RQGIEPI...TYFFRTQA.VTQLRRFRNRTGMNM.......GR.................PANAANAN...ADAMLT.GD.....PMMN.......................QQ.........................AMFQNMMNLQRSNSTFSG....................................NP..AQGQ.DPN
  591-  742 (152.76/44.69)	QQQQQQQQQQPAPQsqpqqqqqqqqgslpqdvqnpamfngqmvnnpRM.RNSMSMP.........Q....G...MNMA...AGLLQ..............................NQQQ................LTPQQ.R........AVR...Q...QRQTE.......MMKLNA....LRKQNNGHEMTV.......DQ.................QKEMDRVP..fPPSLVA.NN.....PHVP.......................QH...........................IKTWAQIKHWAST.......................................NPvtTTGV.DFN
  784-  944 (104.45/28.11)	...........AYQ................................GP.QNGMQIPQN.....HPH....PGMNI.......A.MR..............................PITNEDVQsarqKLGSNSSNYTDDQiR........ELLrnkQ...RQ...ML...E.....QA.VQQ.R......ALAM.......GRavpqppgvvpqkqtqvpPVPVAQQP...PQ..VT.GDlqppnPRPQqaapapkggkaptvnqrskkrpnQD.........................DIVVEM.......PVMNT....................................TP..QQPQaTP.
  946- 1135 (121.18/33.85)	.......AKNSVPQ................................KPvPNQALSQEGLAAM.TPEqrlhVEQTMRLQ...QQALFrgqyfnravaesnwknnlppklldiyneisKAAPAP..........NIVTVSPEQ.KaimtqqlqDSL...EvlaRLDIL.V...LHGFQ.KA.ANQERNIRNLLAMRIqlmrqfkNT.................PEWIINDHftiTPDYLT.GA.....IIFV.......................RK..........................LFQ..MTLVRITNERQS....................................AL..NRAN.TPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.85|      21|      29|    1411|    1432|       6
---------------------------------------------------------------------------
 1411- 1432 (34.84/31.16)	DPLfDDLDDGNGLNMF....SDEAFN
 1440- 1464 (33.01/22.84)	DPT.EDTPDSNDLALAiqtpQDDPIN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.92|      18|      29|     378|     397|       7
---------------------------------------------------------------------------
  378-  397 (26.65/15.01)	NVENIQGQQadGLRSQEAGQ
  408-  425 (34.27/14.55)	NQAPFNNQQ..NLFPQQSGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.63|      18|      19|    1326|    1343|      10
---------------------------------------------------------------------------
 1326- 1343 (32.07/18.45)	TGLMASP..VKPGLATPASS
 1346- 1365 (26.57/13.88)	TPMLRAPsqVVAKSASPATS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.63|      27|     565|     561|     588|      18
---------------------------------------------------------------------------
  561-  588 (42.44/24.06)	QLSGLTNEQLHSfLQTQRRAHANNLTRA
 1143- 1169 (46.19/22.11)	QTTPLNANNLKQ.LQFQQQQHEEALQRA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11426 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAERSDYEKDCNEKLLHIKDTRQRQAAVAIQSGMMPQGGPAMQNQLQGGFPPQMNPNMQASPVAPGQSQMAMGMNGPNQQAAMQQRQQQQQQQAMLQQQQQQQHHQQQQQQQQQQQQQQQQQQQQQQQQQRAQQRPPNGLLLPDDVTGLQNPEAEHVIRLADQMMHKTSPADVEKIKLNLANMNPEQRDYLQRQGI
2) ATKIAQQQNQQNQQNQQNQQNQAQIQQAYQGPQNGMQIPQNHPHPGMNIAMRPITNEDVQSARQKLGSNSSNYTDDQIRELLRNKQRQMLEQAVQQRALAMGRAVPQPPGVVPQKQTQVPPVPVAQQPPQVTGDLQPPNPRPQQAAPAPKGGKAPTVNQRSKKRPNQDDIVVEMPVMNTTPQQPQATPIAKNSVPQKPVPNQALSQEGLAAMTPEQRLHVEQTM
3) ERQSALNRANTPAAQSEQPTQTTPLNANNLKQLQFQQQQHEEALQRARRASSQSAPVPPAPFGAPSPQGVPAYGSGGLAPEKLKLPPPKKRKQSQTGVSSSPVPASA
4) MNPAQFSNPGGGMSGLVKPGMSQQQSQQQRNENAQLIMSS
5) NGLNMFSDEAFNNNAFLGADPTEDTPDSNDLALAIQTPQ
6) QGANQVVTTSAGPTGLMASPVKPGLATPASSTATPMLRAPSQVVAKSASPATSAQQLTPQQGKAKKPGSKPGALDLPSEPALPWANSHMTPQELADTFDPLFDDLDD
7) RRFRNRTGMNMGRPANAANANADAMLTGDPMMNQQAMFQNMMNLQRSNSTFSGNPAQGQDPNAFFGNVENIQGQQADGLRSQEAGQLVVPASSSQMNQAPFNNQQNLFPQQSGQNGQGNGAMNGMGMNPQMFSQQQMQQGLPNGAQQFQAQQAQAQARAHAAAQKAQLAMSGQVNPQAQAQFSQQSPVMPMLNQGMPPGQISPVPMAAQVRPPSRPANMGQHPGGMQAAQPTMQNRPQIPPNLPGPIQEQLSGLTNEQLHSFLQTQRRAHANNLTRANLQQQQQQQQQQPAPQSQPQQQQQQQQGSLPQDVQNPAMFNGQMVNNPRMRNSMSMPQGMNMAAGLLQNQQQLTPQQRAVRQQRQTEMMKLNALRKQNNGHEMTVDQQKEMDRVPFPPSLVANNPHVPQHIKTWAQIKHWASTNPVTTT
8) TAEWMNIPLELQDNSGDGIPGVRVDFDRLE
101
757
1123
1
1421
1313
312
1479
296
980
1229
40
1459
1419
737
1508










Molecular Recognition Features






MoRF SequenceStartStop




NANANA