<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11403
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MDDDDAELRNPFPSPPSHYTKYTSHNLHLLNLLKERVPDTDLAFNQHEILKDQTDVPDWSLTQLEKPRVDWILKGDEPYYDVFGDRWFVKDKIPSLAELGGQQLYPEDPNVDRRPALQTILRSMLVTYSNLTGALLAPPPTQSSSMPPEWQKHVEWITILGQNLMAAANDLRPVQARGNLEMMMKRQLELRKDETRVIHTKCNALEARLLELRASAEDLKQSTSPVRGRYHKSFSVIREICTSQPRRSSTMGGRSQLTQLSDSVVLLDPQKIPCLWFSST |
Length | 280 |
Position | Middle |
Organism | Lentinula edodes (Shiitake mushroom) (Lentinus edodes) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes>
Agaricomycetidae> Agaricales> Omphalotaceae> Lentinula.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.594 |
Instability index | 60.37 |
Isoelectric point | 6.18 |
Molecular weight | 32088.15 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP11403
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 58.64| 18| 21| 172| 191| 1
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172- 191 (27.99/22.08) RPVQARGNleMMMKRQLELR
196- 213 (30.65/18.04) RVIHTKCN..ALEARLLELR
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 48.80| 14| 14| 33| 46| 2
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33- 46 (23.56/13.29) LKERVPDTDLAFNQ
50- 63 (25.23/14.68) LKDQTDVPDWSLTQ
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