<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11386

Description Med12 domain-containing protein
SequenceMQRYHAASCNSAVNNSPIGGTSARDARADSSSLPNNFSLNPRRPSPLAPYKLKCDKEPLSSRLGPPDFHPQTPNCPEETLNREYVQSGYRETVEGLEEAREITLTQVQAFSKPVVLRCRESIRKCLRAINESRAQKRKAGQVYGVPLSGSLLTKPAVFPEQRPCGEDFRKKWIEGLSQQHKRLRSLADHVPHGYRKKYLFEVLIKNNVPLLRATWFIKVTYLNQVRPGPSSISSGAPDRTHLSRSEIWTKDVIDYLQYLLEDFFSKNNPHSTAHNRDLSPQLLYAGSVQHRGDPISAVLDGEEPSLHFKWGYVVRLLQWHHSEGLLLPSLIIDWVLNQLQEKELLEILQLLLPIIYGVLETIVLSQTYVRTLVGIAVRFIREPSPGGSDLVDNSRRAYTTSALVEMLRYLILAVPDTFVALDCFPLPSCVVSYALNDGNFVMKASEDAEKVKINSEVTTVFRSKGIDSQYQSLSFDHVVSTIEKRANKLAKSTTPGYPGHSVAKAVQALDKSLLLGDIRGAYKHLFEDLCDGTVDEGWIAEVSPCLRSSLKWIGTVSLSFICSVFLLCEWATCDFRDFRTAPPNDLKFTGKKDFAQLYVAIRLLKLKIRDSQSSSRRRNESTLGDGLANGHNQLDNHSSRSSVGYEYNIKRNTKSNCSEIFESPGPLHDIIVCWIDQHEVHKGEGIKRLQLFILELVRSGIFYPQAYARQLIVSGIMNMNGPVIDLDRRKRHHRILKQLPGLFMRDALEEARIAEGSQLLQAMRVYTSERRLVLRELLSDQHKNASNANTSVQKQKPNYTSGRDGVSPALVVDQWKTIQSSSNILSSKNVKINADIEELKASISLLLQLPSASSTSTDAGMDESQGSAKRPGGSTSNKMDLAEATPGCEDCRTAKRQKLSEERSSCVQGNSPVPSDDEDTWWMRKGPKPESFKVDPPLKATKQVTRGRQKVVRRTQSLAQLAAARIEGSQGASTSHVCDNKVSCPHHRTGVEGETLKSMDGMRTKHLGDIISIGKGLKQLRFVEKRTITGWLISVVRQLVEETEKTVAKVGQFGRPYIPVDDRSCIRWKLGEDELSAILYLMDVSNDFVSAAKFLLWLLPKVHSIPSSTIHSGRNMLMMPRNAENHVCEVGEAFLLSSLRRYENILVATDLIPEALSTTMELAAALVSSNGRVSGSASLVYARYLLKKYCNVASVIDWEKKFKATNDKRLISELDFGRSLDGDVGFAFGVPAGVEDLDDYFRQKISGGRISRVGVNMRDVVHRNVEDAFKYFIGKERKLLSAGTPKGPAIEKWDDEYQIAQQIIMGLMECIRQTGGAAQEGDPSLVSFAVSAIVGNVGQAIMTALDFTAGNYSNCPSATGSLSFAKCILRIHIICLCLLKEALGERQGRVLEIALATEASTALAGVLAPGKPSRNHDSNSSLANEVSNNSAKPVPGRATKITAAVSALVIGAVIHGVTSLERMVTVLRLKEGLDVIHFVRGTKSSSNGNARSVGAFKGDNSIEVYVHFFRLLVGNCKTISDGLIVEFLGEPSVVSLSRMQRMLPLSLVFPPAYSIFALVIWKPFILNSHVSAREDFHQLYQSLTVAIADSIKHLPFRDVCLRDSQGFYDLVAADSCDAEFASLPEMNGLDMQLKVMAFVPTRARLFLNAIIDCKMPNSIFTQDDGKKVSGQSELKVQHGENETKLLDKLVHVLDTLQPAKFHWQWVELRLLLNEQALFEKLHDMPLVDAIRSSSPSPDKAAASENEKNFFEIILTRLLVRPDAAPLFSELVHLFGRSLEDYMLLQARYLLGGVDVLFGRKSIRQKLIIIAETKGLSTKSQFWKPWGWSSSDLDVTTNRRDKKMFDATSLEEGEVIEEGMDSKRHGKGSQSVDTEGFNDTEQHVTERALVELVLPWIDQSSDDSRNTFANDLIKQLINVEQQINVVTTGASKQAGTVPSGIEVSANKGSSRKGIRGGSPALARRPTVESAALSSPAALRASMSLRLQFLLRLLPVIYAIGEPSGRNLRHMLASVVLRLLGNRVVHEDADMSYCPTQSSQSKREMELLKEAYAVSADFSGENLFDWLLLVLHGLLSSCQPSWLRSKPASKSSHESSKELYGFDREVAESLQNDLDRMQLPDAIRWRIQASMPILFPSVRCSVSCQPPSVPSAALASLQSSISIPGTLNAVFSPLQRNLLPLARGSTNTSGKSKLLTSQQDCDVEIDPWTLLEDGAGSGPSSSNTAVIGGGDHVNLRASSWLKGAVRVRRTDLTYIGAVDDDS
Length2260
PositionKinase
OrganismCephalotus follicularis (Albany pitcher plant)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Oxalidales> Cephalotaceae> Cephalotus.
Aromaticity0.07
Grand average of hydropathy-0.243
Instability index47.90
Isoelectric point8.60
Molecular weight250070.63
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11386
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     206.48|      49|     182|    1964|    2012|       1
---------------------------------------------------------------------------
 1964- 2012 (83.14/50.58)	PTVESAA......LSS.PAALRASMSLR..LQF..LLR.LLPVIYAIGEPSGRNLRHMLAS
 2033- 2087 (64.29/37.28)	PTQSSQSkremelLKE.AYAVSADFSGEnlFDW..LLL.VLHGLLSSCQPSW..LRSKPAS
 2145- 2195 (59.05/33.58)	PSVPSAA......LASlQSSISIPGTLN..AVFspLQRnLLPLARGSTNTSGKS..KLLTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     385.10|     127|     184|    1053|    1187|       2
---------------------------------------------------------------------------
 1053- 1187 (201.68/148.47)	FGRPYIPVDDRSCIRWKLGEDELSAI.LYLMDVSNDFV.SAAKFLL....WLL....PKVHSIP..SSTIHSGRNMLM..MP..RNAENHVCEvGEAFLLSslrryENILVATDLIPEALSTTMELAAALVSSNGRVSGsaSLVYARYLLK
 1228- 1370 (183.42/116.19)	FGVPAGVEDLDDYFRQKISGGRISRVgVNMRDVVHRNVeDAFKYFIgkerKLLsagtPKGPAIEkwDDEYQIAQQIIMglMEciRQTGGAAQE.GDPSLVS.....FAVSAIVGNVGQAIMTALDFTAGNYSNCPSATG..SLSFAKCILR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.19|      29|     180|      39|      67|       3
---------------------------------------------------------------------------
   39-   67 (54.73/33.62)	LNPRRPSPLAPYKLKCDKEPLS.SRLGPPD
  222-  251 (48.46/28.80)	LNQVRPGPSSISSGAPDRTHLSrSEIWTKD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11386 with Med12 domain of Kingdom Viridiplantae
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