<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11385

Description Pkinase domain-containing protein/U-box domain-containing protein
SequenceMALVSPVPTIKLPVGPIRYGEIRVMASTREIVEEPVAQVIEEKMYVALGKEVKENRSILIWALHNSGGKRICIIHVHVPAQMIPLLGTKFPASSLKEQEVRAYREIERQSMENILNEYLVICSQMGVRAERYFIEKDCIEEGILELISRHGIRKLVMGAAAEKHCSKKMMDLKSKKAIYVRLEAPASCHIWFVCKGSLIHTREGISEGAGIEVASSSLQASPSIETGQSNHLRSQSLPLGHNNFTRLTNPAQDLFSRIKFGHLDGRVGRVTRLTSPDGTAGLTSLRSRLDTEESFDEQDRFSRMSLSQSSNLSSSSSSPSYPGLRTGERDSGLDLAALPQFKEVLHHSSPPSVLDGNIDGPPLYEQLEQAMTEAENSRREAFEEAIRRGKAEKGAIEAIRKAKASEAFYNEEFKLRKEIEEALAKEQEELEKIKREQEGVMEELQFTLDEKLLLERQVAECDEMVKELEQKIISAVELLQNYKKERDELQMERDNALKEAEDLRKSRAEASTANMPRFYSEFSFTEIGEACHNFDPSLKIGEGGYGSIYRGVLRHTQVAIKMLHSYSLQGPSEFQQEVDVLSKTRHPNLVTLIGACPEAWTLIYEYLPNGSLEDRLSCRDNSPPLSWQTRIRIAAELCSVLIFLHSSKPHSVVHGDLKPANILLDANFVSKLSDFGISRLLSHDGTLSSNSTLCCRTDPKGTFAYMDPEFLATGELTPKSDVFSFGIILLRLMTGRQALGIIKEVQYALDKGNLKTLLDPLAGDWPFVQAEQLAYMALRCCEMNRRCRPDLGSEVWRILEPMRASCGGSSSFRLGSEEHCQPPPYFICPIFQEVMRDPHVAADGFTYEAEALRGWLDSGHDTSPMTNIKLEHSNLVPNRALRSAIQEWLQQN
Length892
PositionTail
OrganismCephalotus follicularis (Albany pitcher plant)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Oxalidales> Cephalotaceae> Cephalotus.
Aromaticity0.07
Grand average of hydropathy-0.374
Instability index56.84
Isoelectric point5.79
Molecular weight100145.03
Publications









Function






Annotated function

Functions as an E3 ubiquitin ligase.



ECO:0000256	ARBA:ARBA00003861

GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11385
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.20|      22|      24|     380|     403|       1
---------------------------------------------------------------------------
  380-  399 (28.19/16.42)	....EAF..EEAIRRGKAEKGAIEAI
  402-  423 (20.41/13.06)	AKasEAFynEEFKLRKEIE....EAL
  424-  444 (25.60/10.64)	AKeqEEL..EK.IKR..EQEGVMEEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.82|      14|      18|     205|     218|       2
---------------------------------------------------------------------------
  205-  218 (21.91/12.41)	ISEGAGIEVASSSL
  224-  237 (23.91/14.16)	IETGQSNHLRSQSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.65|      12|      24|     239|     250|       3
---------------------------------------------------------------------------
  239-  250 (24.48/16.44)	LGH.....NNFTRLTNP
  260-  276 (18.17/10.35)	FGHldgrvGRVTRLTSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     368.35|      99|     405|     277|     379|       4
---------------------------------------------------------------------------
  277-  379 (166.00/130.79)	DGT.AGLTSLRSRLDTEESFDEQD.RFsrmsLSQSS...NLSSSSSSPSYPG...LR..TGERDSGLDLAA.LPQ...FKEVLHHSSPPSVLDGNIDGPP...LY..EQLE.QAMTEAENSRR
  607-  680 (72.67/46.56)	...............................LPNGSledRLSCRDNSP..P....LS..WQTR...IRIAAeLCSvliF...LHSSKPHSVVHGDLK.PAnilLD..ANFV.SKLSDFGISRL
  684-  786 (129.68/92.29)	DGTlSSNSTLCCRTDPKGTFAYMDpEF....LA.TG...ELTPKSDVFSF.GiilLRlmTGRQALGI.....IKE...VQYALDKGNLKTLLDPLAGDWP...FVqaEQLAyMALRCCEMNRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.28|      23|      24|     470|     493|       5
---------------------------------------------------------------------------
  470-  493 (32.08/26.71)	QKIISAvELLQNYKKERDELQMER
  495-  517 (34.20/23.28)	NALKEA.EDLRKSRAEASTANMPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.57|      17|      24|     135|     157|       6
---------------------------------------------------------------------------
  135-  152 (24.14/13.42)	EKDCIEEgILELISRHGI
  162-  178 (27.42/11.51)	EKHCSKK.MMDLKSKKAI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11385 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HHSSPPSVLDGNIDGPPLYEQLEQAMTEAENSRREAFEEAI
2) RVTRLTSPDGTAGLTSLRSRLDTEESFDEQDRFSRMSLSQSSNLSSSSSSPSYPGLRTGERD
346
269
386
330










Molecular Recognition Features






MoRF SequenceStartStop




NANANA