Description | Med21 domain-containing protein |
Sequence | MDIISQLQEQVNTIATVAFNTFGTLQRDAPPVRLSPNYPEPPPPPIPTDDSSNFSDLPKLLSVDLVKAAKKFDALVAALPLSEGGEEAQLKKIAELQTENDAVGQELQRQLEAAEKELKLVQELFNEAADNCFNLKKPD |
Length | 139 |
Position | Middle |
Organism | Cephalotus follicularis (Albany pitcher plant) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Oxalidales> Cephalotaceae> Cephalotus. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.409 |
Instability index | 45.66 |
Isoelectric point | 4.44 |
Molecular weight | 15241.03 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP11353 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 78.07| 30| 44| 61| 92| 1 --------------------------------------------------------------------------- 61- 92 (35.46/29.50) LSVDLVKAAKKFDaLVAALpLSEGGEEA.QLKK 107- 137 (42.61/25.02) LQRQLEAAEKELK.LVQEL.FNEAADNCfNLKK --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EEAQLKKIAELQTEN 2) TDDSSNFSDLPKLLSVDLVKAAKKFDALVAALPL | 86 48 | 100 81 |
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Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab