<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11320

Description ATP-dependent DNA helicase
SequenceMFCFTSCLGAVADFWERRRRRKGKHAAVDSAGESMESEAIQEDLQNLDVELKDVQGQISALIEHQDRLYERKSELKTLLKALAASGSPVASSGGSSAIENWSETFEWDSRADDVRFNVFGISKYRANQKEIINAIMTGRDVLVIMAAGGGKSLCYQLPAMLRGGTTLVVSPLLSLIQDQVMGLAALGISAYMLTSTSGKENEKFVYKALEKGEDDLKILYVTPEKVSKSKRFMSKLEKCHNAGRLSLISIDEAHCCSQWGHDFRPDYKNLSILKTQFPKVPMVALTATATQKVQNDLIEMLHIPKCVKFVSSVNRPNLFYSVREKSAVGKLVVDEIAEFIRESYSNNESGIVYCFSRKECEQIAGDLRERGISADYYHADMDANMREKVHMRWSKNKLQVIVGTVAFGMGINKPDVRFVIHHSLSKSMETYYQESGRAGRDGLPSECILFFRSADVPRQSSMVFYEYSGLQNLYDIVRYCQSKTKCRRSAFFRHFGEPSQDCNGMCDNCALSSEVKEVDVSDLSKLVVSMVQETQAKDQRVTMLQLGDKLRNKHKDLIAELKRDEVEHLVIKLIVDSVLKEEFQHTPYSTNAYVTMGPLANQLLQGRKTIKMETSSRQTKKLKRSITFSGLELKLDELRKEISAADGSILPHTVLSTQQIGSISSQKPVSLQELESIIGKLKTEKYGDRILEEVMRHEAVSEQLVEDPTKEETCKSRLRKRAKTQKDVVLVESSGEEEA
Length739
PositionUnknown
OrganismArabidopsis thaliana (Mouse-ear cress)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Brassicales> Brassicaceae> Camelineae> Arabidopsis.
Aromaticity0.07
Grand average of hydropathy-0.390
Instability index43.60
Isoelectric point8.00
Molecular weight83196.29
Publications
PubMed=11130712
PubMed=27862469

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro
GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP11320
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     258.66|      69|     304|     271|     340|       1
---------------------------------------------------------------------------
  272-  340 (111.52/69.33)	ILKTQFPKVPMVALTATATQKVQN.DLIEMLHIPKCVKF.VSSVNRPNLFYSVREKSAVGKLVVDEIAEFI
  528-  576 (53.10/28.78)	........VSMVQETQAKDQRVTMlQLGDKLR.NKHKDL.IAELKRDEV......EHLVIKLIVD......
  578-  642 (94.04/53.56)	VLKEEFQHTPYSTNAYVTMGPLAN.QL...LQGRKTIKMeTSSRQTKKLKRSITF.SGL.ELKLDELRKEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.65|      22|     299|     105|     140|       2
---------------------------------------------------------------------------
  119-  140 (39.38/52.79)	FGISKY.......RANQKEIINAIMTGRD
  186-  214 (31.27/11.81)	LGISAYmltstsgKENEKFVYKALEKGED
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP11320 with Med34 domain of Kingdom Viridiplantae

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