<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11311

Description Kinase with adenine nucleotide alpha hydrolases-like domain-containing protein
SequenceMWLPKANGAKKETGSGSVAVAIDKDKGSQHALKWTIDNLASRGQTISLIHVLCRSHSSSDLEEGTPQQKQQMEKIAKDLFVSFHCYCSRKEINCRDILLEDADKVRAITEYVSSSAIENLVVGSASRNGFMRRFKTDLPTTVSKSAPDFCNVYVISKGKIASVRNASRPAPYQNSMQQCEIDNHHPHTPDKAPKYHDHPNSAGSTPSRPRKSVEADRSPLVKRKPYGDFYDSDSDLSFISPSSHRDSDISFISSGRPSVERSSFSLDFPESARTSRMSTSSEQSIGSNRLGIKFSDPDFLNESSTFSEESGRTSSYSSQSLDDVEAEMKRLRLELKQTMDMYSTACKEALSARQQATELQKLRTEEERRLEEAKSSEEAAMSIVEKERAKAKAALEAAEAAKRLAEVESKRRLTAEMKTMKESDSFSRGFVRYRKYTVDEIEEATSNFAESQKVGEGGYGPVFRGFLDHTSVAVKVLRPDAAQGRSQFQKEVEVLSCIRHPNMVLLLGACPEFGILVYEYMAKGSLEDRLFMRGNTPPITWQLRFRIAAEIATGLLFLHQTKPEPIVHRDLKPGNVLLDYNYVSKISDVGLARLVPAVAENVTQYRVTSAAGTFCYIDPEYQQTGMLGVKSDVYSLGIMLLQILTAKQPMGLAYYVEQAIEEGTLKDMLDPAVPDWPIEEALSLAKLSLQCAELRRKDRPDLGKEILPELNRLREIGEESLESVFYAGNQGKSPNTSQVSIPESPAAESQS
Length751
PositionTail
OrganismArabidopsis thaliana (Mouse-ear cress)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Brassicales> Brassicaceae> Camelineae> Arabidopsis.
Aromaticity0.07
Grand average of hydropathy-0.525
Instability index51.53
Isoelectric point6.16
Molecular weight83584.29
Publications
PubMed=11130712
PubMed=27862469

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11311
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.52|      14|      14|     241|     254|       1
---------------------------------------------------------------------------
  241-  254 (25.68/14.87)	PSSHRDS.DISFISS
  257-  271 (20.84/10.70)	PSVERSSfSLDFPES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.91|      30|     349|     358|     392|       2
---------------------------------------------------------------------------
  327-  356 (45.37/24.76)	EMKRLRLELKQTMDMYSTACKEALS..ARQQA
  358-  389 (40.55/27.25)	ELQKLRTEEERRLEEAKSSEEAAMSivEKERA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.33|      26|      58|      57|      82|       3
---------------------------------------------------------------------------
   57-   82 (44.79/29.75)	SSSDLEE...GTPQQKQQMEKIAKDL..FVS
  113-  143 (34.54/21.24)	SSSAIENlvvGSASRNGFMRRFKTDLptTVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.40|      25|      35|     406|     430|       5
---------------------------------------------------------------------------
  406-  430 (42.07/29.93)	EVESKRRLTAEMKTMKES..DSFSRGF
  440-  466 (38.32/26.56)	EIEEATSNFAESQKVGEGgyGPVFRGF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11311 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RNASRPAPYQNSMQQCEIDNHHPHTPDKAPKYHDHPNSAGSTPSRPRKSVEADRSPLVKRKPY
2) RQQATELQKLRTEEERRLEEAKSSEEAAMSI
3) SSFSLDFPESARTSRMSTSSEQSIGSNRLGIK
164
353
262
226
383
293










Molecular Recognition Features






MoRF SequenceStartStop




1) NRLREIGEESLESVFYAGN
711
729