<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11307

Description "BMA-SUR-2, isoform n"
SequenceMGTTTEAIATSATSLTAAVGNDAEKLQWIVLNQVEGVQMREMFWDLSKDVDVDVLACSEAVKMLRTMTEEEKTQCCKASLSLLSNKDDPRYIHYERILSSIFMIACNEGVLPLSDCCELLILCTNFSLTTPMDSRKFEYMQKNLHLIDYKGLRNILKLLVVERMQEVPSTITHHHRHMLLPVENMLLTLIDRQLNLLPCIFTITELHRVSNNSRAFLLPRVAKKFNDMFISFRPLTEMVTIIGRSWLYPIAAHISFPVSTPSWKLEVTTTRLHQRAHLPYKSELFAPQSFLLYTLLRQPRGKDTISYVMRQNTSLTPQRLQCDELLHMIILEAMSEMEKTDTRLDDPANQYQWMNITQTVTFSLLHGNASFARLLKILYESLSETVYRKGRDELMWVILQYVAVYIDRVSNEEMVRVAEIYNLLYSDEQTWSGADTDPLLFVRFLVPAAIWIHFYKKLGNSHTEILPKPSESLWRQIQFLQERTADSDPNIQNVADHNAVLAAVANAYSSDMPNFQKLVLTAVDVFLDGSPEEMNTVWHLPYGIISYSKKTPLPLSLIDSLTFHARNHLFQLCLLKLTAMLSIQQAQKVPSPATIDTLVRLAVTTEFEYGVKQVLALLSSTLASVNKSTNLGPAQQDRSRDLLFVLCDILSYRFISYPFPVGSKINLMLWCYTALGNSQVQMNIVLCSALEQVMMRYWMWNSPQEMFYLSNAFLGMEMTAEMMQRCNVNFCWPLSINRTYSSQLIGCNVDDGAADTVIYDELMHRVIQEVHQVQEIIYAQGLAAEEQLLKFFSGERRQTIFCVVYNMLFETKKIHPVIYSVLSSMNNKELTATINKFTDYFIFIFKKNLPSDDQQFTAMIGILNDMAFNLHLIPLDRLLISLVLHPTDDGATEIAMLIIHSLVGSYPDLHNRITALVHIIPSNKIGNSGAAFFNKMSEYYSQFPELSYREMEAKMRREMQIELGMRPIEQSTVNPELHMPIYYGNIMERILPIVDIILLRAIETVVADQLFTTLLMCFKPCYRYHPQPAAYMYSVLYCLDKTISHTVRARDFVLEICGQLEDRDGKYALLTPSFISDNHQLSLPSQFCQALVDRILQASNYAHQPPAFVYKDWRFAEMPPAGQALTGACIELLASPHAPVITAHALIDLVFIRPLHQPYATINAVALILTALPVSFQQVFYDHIVSVLDSEALHGDPSVCFGSLESECLLLTENQLLTNLALGHAYLQHCNTSSLAALPEFVRDQLAPKLVTEAQLIFVLRLVVPILQRFYDAKERSKQIQDLAVDVYKMTVKVNERVGLLKYEDSICDFLYHMKYMYVGDFVKNEAEQAIQRLSPSMRNKLKYISHTQMNTAIDLPHKLAPGPSNLDVVRRDVWMEHGAASHTVQFSQTMKLIRGSSWYWGNMSWKDAEKVLMSQLPGTYLVRDSASDRYIFTISYRTKHSVHHTRLAQHGGNFCLGGPNSLVKANSLVSFIENSLQSCCKRRICMLMHPKSDSTGIETLELNHLLRRHELLPSLKYLCRVVIRNCVEKELLASLPLPSNMICYLEDPKYFVPPCLYQ
Length1559
PositionTail
OrganismBrugia malayi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Brugia.
Aromaticity0.09
Grand average of hydropathy0.001
Instability index45.19
Isoelectric point6.28
Molecular weight178267.93
Publications
PubMed=17885136

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process
intracellular signal transduction	GO:0035556	IEA:InterPro
negative regulation of signal transduction	GO:0009968	IEA:UniProtKB-KW
regulation of growth	GO:0040008	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11307
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     153.81|      38|      38|     545|     582|       1
---------------------------------------------------------------------------
  545-  582 (65.29/43.15)	ISYSKKTPLPLSLIDSLTFHARNHLFQLCLLKLTAMLS
  583-  619 (56.17/36.02)	IQQAQKVPSP.ATIDTLVRLAVTTEFEYGVKQVLALLS
  623-  647 (32.35/17.40)	ASVNKSTNLGPAQQD....RSRDLLFVLC.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.55|      20|      38|    1210|    1229|       2
---------------------------------------------------------------------------
 1210- 1229 (34.66/21.19)	LLTENQLLTNLALGHAYLQH
 1250- 1269 (32.89/19.73)	LVTEAQLIFVLRLVVPILQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     151.00|      36|      37|    1072|    1107|       5
---------------------------------------------------------------------------
 1029- 1068 (25.51/10.10)	AAymysVL.YCLDKtisHTVrarD.FVLEICGQLEDR...DGKYA...
 1072- 1105 (54.13/29.38)	......PS.FISDN...HQL...S.LPSQFCQALVDRILQASNYAHQP
 1106- 1139 (43.05/21.92)	P.......aFVYKD...WRF...AeMPPA.GQALTGACIELLASPHAP
 1142- 1158 (28.31/11.98)	TA....H.........................ALIDLVFIRP..LHQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.37|      33|      40|     905|     942|       6
---------------------------------------------------------------------------
  920-  961 (47.08/36.26)	IPSNKIGNSGAAFFNKMSEYYsqfpelsyrEMEAKMRREMQI
  963-  996 (52.29/31.32)	LGMRPIEQSTVNPELHMPIYY........gNIMERILPIVDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.19|      16|     359|      14|      31|      10
---------------------------------------------------------------------------
   14-   31 (23.96/19.94)	SLTAAV...GNDaeKLQWIVL
  381-  399 (24.22/13.48)	SLSETVyrkGRD..ELMWVIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.74|      26|      29|     192|     219|      14
---------------------------------------------------------------------------
  192-  219 (40.14/34.65)	RQLNLLPCIF.TITELhrVSNNSRAFLLP
  223-  249 (43.61/29.68)	KKFNDMFISFrPLTEM..VTIIGRSWLYP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11307 with Med23 domain of Kingdom Metazoa
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