<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11306

Description "BMA-SUR-2, isoform d"
SequenceMGTTTEAIATSATSLTAAVGNDAEKLQWIVLNQVEGVQMREMFWDLSKDVDVDVLACSEAVKMLRTMTEEEKTQCCKASLSLLSNKDDPRYIHYERILSSIFMIACNEGVLPLSDCCELLILCTNFSLTTPMDSRKFEYMQKNLHLIDYKGLRNILKLLVVERMQEVPSTITHHHRHMLLPVENMLLTLIDRQLNLLPCIFTITELHRVSNNSRAFLLPRVAKKFNDMFISFRPLTEMVTIIGRSWLYPIAAHISFPVSTPSWKLEVTTTRLHQRAHLPYKSELFAPQSFLLYTLLRQPRGKDTISYVMRQNTSLTPQRLQCDELLHMIILEAMSEMEKTDTRLDDPANQYQWMNITQTVTFSLLHGNASFARLLKILYESLSETVYRKGRDELMWVILQYVAVYIDRVSNEEMVRVAEIYNLLYSDEQTWSGADTDPLLFVRFLVPAAIWIHFYKKLGNSHTEILPKPSESLWRQIQFLQERTADSDPNIQNVADHNAVLAAVANAYSSDMPNFQKLVLTAVDVFLDGSPEEMNTVWHLPYGIISYSKKTPLPLSLIDSLTFHARNHLFQLCLLKLTAMLSIQQAQKVPSPATIDTLVRLAVTTEFEYGVKQVLALLSSTLASVNKSTNLGPAQQDRSRDLLFVLCDILSYRFISYPFPVGSKINLMLWCYTALGNSQVQMNIVLCSALEQVMMRYWMWNSPQEMFYLSNAFLGKQGKLAVIFNTANPAFCDPQHGNVSVEQQYTNSHISLELLRCLLLSMFRSLKMTGMEMTAEMMQRCNVNFCWPLSINRTYSSQLIGCNVDDGAADTVIYDELMHRVIQEVHQVQEIIYAQGLAAEEQLLKFFSGERRQTIFCVVYNMLFETKKIHPVIYSVLSSMNNKELTATINKFTDYFIFIFKKNLPSDDQQFTAMIGILNDMAFNLHLIPLDRLLISLVLHPTDDGATEIAMLIIHSLVGSYPDLHNRITALVHIIPSNKIGNSGAAFFNKMSEYYSQFPELSYREMEAKMRREMQIELGMRPIEQSTVNPELHMPIYYGNIMERILPIVDIILLRAIETVVADQLFTTLLMCFKPCYRYHPQPAAYMYSVLYCLDKTISHTVRARDFVLEICGQLEDRDGKYALLTPSFISDNHQLSLPSQFCQALVDRILQASNYAHQPPAFVYKDWRFAEMPPAGQALTGACIELLASPHAPVITAHALIDLVFIRPLHQPYATINAVALILTALPVSFQQVFYDHIVSVLDSEALHGDPSVCFGSLESECLLLTENQLLTNLALGHAYLQHCNTSSLAALPEFVRDQLAPKLVTEAQLIFVLRLVVPILQRFYDAKERSKQIQDLAVDVYKMTVKVNERVGLLKYEDSICDFLYHMKYMYVGDFVKNEAEQAIQRLSPSMRNKLKYISHTQMNTAIDLPHKLAPGPSNLDVVRRDVWMEHGAASHTVQFSQTMKLIRGSSWYWGNMSWKDAEKVLMSQLPGTYLVRDSASDRYIFTISYRTKHSVHHTRLAQHGGNFCLGGPNSLVKANSLVSFIENSLQSCCKRRICMLMHPKSDSTGIETLELNHLLRRHELLPSLKYLCRVVIRNCVEKELLASLPLPSNMICYLEDPKYFVPPCLYQICIYNGIMFILIFVLANNQALIMK
Length1638
PositionTail
OrganismBrugia malayi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Brugia.
Aromaticity0.09
Grand average of hydropathy0.023
Instability index44.47
Isoelectric point6.41
Molecular weight187139.42
Publications
PubMed=17885136

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process
intracellular signal transduction	GO:0035556	IEA:InterPro
negative regulation of signal transduction	GO:0009968	IEA:UniProtKB-KW
regulation of growth	GO:0040008	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11306
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     153.81|      38|      38|     545|     582|       1
---------------------------------------------------------------------------
  545-  582 (65.29/42.53)	ISYSKKTPLPLSLIDSLTFHARNHLFQLCLLKLTAMLS
  583-  619 (56.17/35.49)	IQQAQKVPSP.ATIDTLVRLAVTTEFEYGVKQVLALLS
  623-  647 (32.35/17.15)	ASVNKSTNLGPAQQD....RSRDLLFVLC.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.03|      35|      36|    1127|    1162|       2
---------------------------------------------------------------------------
 1100- 1133 (34.97/18.60)	HTVrarD.FVLEICGQLEDR...DGKYA......lltPS.FISDN
 1134- 1167 (52.97/32.18)	HQL...S.LPSQFCQALVDRILQASNYAHQP..P.....aFVYKD
 1168- 1202 (31.09/20.33)	WRF...AeMPPA.GQALTGACIELLASPHAPviT..aHA.LI...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.55|      20|      37|    1265|    1284|       3
---------------------------------------------------------------------------
 1265- 1284 (34.66/27.44)	LLTENQLLTNLALGHAYLQH
 1305- 1324 (32.89/25.57)	LVTEAQLIFVLRLVVPILQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.37|      33|      40|     960|     997|       4
---------------------------------------------------------------------------
  975- 1016 (47.08/39.87)	IPSNKIGNSGAAFFNKMSEYYsqfpelsyrEMEAKMRREMQI
 1018- 1051 (52.29/34.44)	LGMRPIEQSTVNPELHMPIYY........gNIMERILPIVDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     126.98|      34|     868|     509|     542|       9
---------------------------------------------------------------------------
  183-  214 (28.31/15.60)	.......ENMLLTLIDRQLNLLPciftiTELHRV....SNNSR
  215-  249 (38.25/24.11)	AFLLPRVAK...KFNDMFISFRP....lTEMVTIigrsWLYP.
  509-  542 (60.42/43.05)	SSDMPNFQKLVLTAVDVFLDGSP.....EEMNTV....WHLPY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.39|      30|     526|    1057|    1086|      13
---------------------------------------------------------------------------
 1057- 1086 (56.42/36.43)	IETVVADQLFTTL.....LMCFKPCYRYHPQPAAY
 1579- 1613 (49.97/31.34)	IRNCVEKELLASLplpsnMICYLEDPKYFVPPCLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.02|      25|      40|     855|     880|      16
---------------------------------------------------------------------------
  855-  880 (38.77/30.00)	IFCVVYNMLFETKKIHPVIySVLSSM
  897-  921 (43.25/27.93)	IFIFKKNLPSDDQQFTAMI.GILNDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.47|      31|     666|     784|     814|      18
---------------------------------------------------------------------------
  731-  784 (32.94/19.71)	FCDPqhgnVSVEQQYtnshiSLELLRCLLlsmfrslkMTGMEMTaemmqrCNVN
  785-  815 (58.53/41.49)	FCWP....LSINRTY.....SSQLIGCNV........DDGAADT......VIYD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11306 with Med23 domain of Kingdom Metazoa
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