<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11288

Description Serine/threonine-protein kinase ssn3
SequenceMSLLDDWSTSNILVNDPMRVYRAKRDAARKRVTDKYSILGFISSGTYGRVYKAQSKDSDGRIHAIKKFKPDKEGDVVTYTGISQSAIREIALNREISHENIVALKEVILEDKSIYMVFEYAEHDFLQVIHHHSQTLRSSITQPVLKSLTYQLINGLLYLHEAHIIHRDLKPANILITSAGVVKIGDLGLARLTHQPLQPLFLGDKVVVTIWYRAPELLLGAKHYNKSVDIWAVGCVMAELASLRPIFKGEEAKLDSKKNVPFQKDQLLKIFEVLGTPSERDWPKIKDLPEYQNMRRLDPYTNRLIEWCQSRIRPHGTDLLAQLFAYDPDKRLTAAEALQHKWFQEEPRPTRNAFDSLPSHQIPPHRRITHDDAPSMMPVAAAGSQVQAQVSQVQATAQAHLSQLSHSHSNHSKVGSAASFASLSAGGNGTGSRKKARLG
Length439
PositionKinase
OrganismTrametes pubescens (White-rot fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Polyporales> Polyporaceae> Trametes.
Aromaticity0.07
Grand average of hydropathy-0.386
Instability index40.60
Isoelectric point9.38
Molecular weight49363.85
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11288
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.34|      24|      27|     159|     184|       1
---------------------------------------------------------------------------
  159-  184 (35.60/29.37)	LHEAHIIHRDLKPanILITSAGVVKI
  187-  210 (40.74/26.80)	LGLARLTHQPLQP..LFLGDKVVVTI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     138.58|      32|      34|     306|     337|       2
---------------------------------------------------------------------------
  277-  302 (30.03/16.68)	........P..SERDWpkIKDLPEYQNMRRLDPYTN
  306-  337 (56.11/37.64)	EWCQSRIRP..HGTDL..LAQLFAYDPDKRLTAAEA
  341-  373 (52.45/34.70)	KWFQEEPRPtrNAFDS..LPS.HQIPPHRRITHDDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.47|      19|      29|      20|      48|       3
---------------------------------------------------------------------------
   20-   41 (26.90/36.72)	VYRAKRDAARKRVtdkYSILGF
   50-   68 (32.57/15.13)	VYKAQSKDSDGRI...HAIKKF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11288 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EALQHKWFQEEPRPTRNAFDSLPSHQIPPHRRITHDDAPSMMPVAAAGSQVQAQVSQVQATAQAHLSQLSHSHSNHSKVGSAASFASLSAGGNGTGSRKKARLG
336
439










Molecular Recognition Features






MoRF SequenceStartStop




1) SRKKARLG
2) YGRVYK
432
47
439
52