<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11268

Description Uncharacterized protein
SequenceMFGKSFPFYNSVAGFYPQSTDSRRPPGTGYTSKVRVRDRYHIVGFISSGTYGRVYKAIGKNGQKGEFAIKKFKPDKEGEVVQYTGLSQSAIREMALCSELDHANVVQLAEIILEDKCIFMVFEYTEHDLLQIIHHHTQPQRHAIPAAMVKSILFQLLNGLLYLHTNWVLHRDLKPANILVTSSGAIRIGDLGLARLFYKPLNSLFSGDKVVVTIWYRAPELLMGSRHYTPAVDLWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMMKIMEIMGLPTKETWPGIVSMPEYAQLQSLAVSRAPGHFSRSSNLEGWYQSCLKNNGYSANASAGTPGADGYDLLARLLEYDPTKRITAQEALEHPYFRSGGAISANCFEGFEGKYPHRRVTQDDNDIRSGSLPGTKRSGLPDDTLMGRAAKRLKE
Length427
PositionKinase
OrganismAspergillus aculeatus ATCC 16872
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus> Aspergillus subgen. Circumdati.
Aromaticity0.10
Grand average of hydropathy-0.304
Instability index41.25
Isoelectric point9.18
Molecular weight47822.30
Publications
PubMed=28196534

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP11268
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     134.74|      34|     123|     117|     150|       2
---------------------------------------------------------------------------
  117-  150 (64.94/42.63)	CIFM.......VFEYTEHDLLQIIHHHTQP.QRHAIPAAMVK
  216-  238 (33.42/18.81)	..............YRAPELLMGSRHYT.P....AVDLWAVG
  239-  273 (36.38/21.05)	CIFAellslrpIFKGEE...AKMDSKKTVPfQRN....QMMK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     168.40|      52|     278|       5|      65|       3
---------------------------------------------------------------------------
    5-   65 (74.80/80.21)	SFPFYNSVagfypQSTDSRRPPGTgYTSKVRVRDRYHivGFISSGTYGRVYKAiGKNGQKG
  291-  342 (93.61/65.30)	SMPEYAQL.....QSLAVSRAPGH.FSRSSNLEGWYQ..SCLKNNGYSANASA.GTPGADG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP11268 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) RRVTQDDNDIRSGSLPGTKRSGLPDDTLMGRAAKRL
390
425

Molecular Recognition Features

MoRF SequenceStartStop
1) AKRLKE
422
427