Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MADGTTLNTAFAPPPPLWKHFTPENVRKLEQIKKEASKGEDGKPQKKDWSAKELRSLTLPPELRFLVPPDIPSEQYSVFGEMQSLSTALHPLEDQGITQLYPSSPKPGANGEPAPQPEQPLNHAYYLLKISKSLLLNFLEFVGILSQTPEQFEPKVEDIRNLFINAHHLLNLYRPHQARESLIMMMEEQLSRTKEEIQHMDKLKEELNAALDQLAAEGADVGSTIQPAIEDDKNAVKLKEQATEDSRLLWDIIDGKVDS |
Length | 259 |
Position | Middle |
Organism | Aspergillus versicolor CBS 583.65 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus> Aspergillus subgen. Nidulantes. |
Aromaticity | 0.06 |
Grand average of hydropathy | -0.607 |
Instability index | 45.62 |
Isoelectric point | 5.04 |
Molecular weight | 29206.80 |
Publications | PubMed=28196534 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP11164 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 224.00| 72| 113| 40| 114| 1 --------------------------------------------------------------------------- 40- 114 (117.42/76.46) EDGKPQKKD.....WSAKELRSLTLPPELR.FLVPpdIPSEQYS.VFGEMQSLSTALHPLeDQGITQLYPSSPKPGANGEPA 150- 228 (106.57/60.05) EQFEPKVEDirnlfINAHHLLNLYRPHQAReSLIM..MMEEQLSrTKEEIQHMDKLKEEL.NAALDQLAAEGADVGSTIQPA --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) QKKDWSAKELRSLTLPPELRF 2) RLLWDIID 3) WKHFTPENVRKLEQIKKEASKGE | 45 247 18 | 65 254 40 |
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