<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11151

Description Uncharacterized protein
SequenceMTAAPVSPREIRERLLQAIDKQSNIQNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTSNEDLAKRAKKLLRNWQKLIEPVTQNEQLVRGIPNLPGSANGGGSHNCKADPAPTNLLAGKPIQELKGRNDIQKAHSPKADKTPKRKRKEHRDGGQGTPGHLSKPNHELFQNSSPPPTNGIGGSPPDNLPSPLDGGLQSNNRLEPAENDKHGKIPINAVRPHTNSPGLVKHPSTSSLLKVVVLQQHSGGLDDALSHQPRSPRCSSFSPRGTRAELATRQHTTYAPKGSAPSPSQRLPGVDSAHQSPLHPSTPPATAKRLESPRQDRVSSPHKPVEQLPSTDCHQVLPRTSQQHIPRSSLVDSQTPRTGFSPESSKLDSDDAASGSDNLKRKKSRLRIECEGQSADGTGKPARVKKERRLTFDVITGQIKPLTLKDPAQVESSAPTEQHRTETDKQDLTLSLPSPFQLTNWKELSGNEIIQSYLHRQSSLLSSSGIQTQSAHYYMSEYLKQEECTKRESRKTHVLVPIVLPSDLPGRTREITSSDTDRIQNQHWPGVNGCHDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length597
PositionUnknown
OrganismXenopus laevis (African clawed frog)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Amphibia> Batrachia> Anura> Pipoidea> Pipidae> Xenopodinae> Xenopus> Xenopus.
Aromaticity0.03
Grand average of hydropathy-0.907
Instability index62.59
Isoelectric point9.32
Molecular weight65770.88
Publications
PubMed=27762356

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11151
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     470.46|      89|      91|      94|     182|       1
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   58-  133 (97.88/37.31)	NDVRKKT.S..NEDL..A..KRAK.......K.........................LLRNWQkliEP..VT......qneqlVRGIP..NLPGSANGGG....S.HNCKAD........PAPTNLLAGK.PIQELKGR
  134-  226 (138.23/55.49)	NDIQKAH.SPKADKT..P..KRKR.......KEH.R...D..GGQGTPGHLSKPNHELFQNSS...PP..PT.........ngIGGSPpdNLPSPLDGGL....Q.SNNRLE........PAE.NDKHGKiPINAVRPH
  227-  302 (79.89/29.20)	TN......SPGLVKH..P..STSSllkvvvlQQH.S...G..GLDDALSH..QPRSPRCSSFS...PR..GT............................raelA.TRQHTT........YAPKG.SAPS.PSQRLPG.
  303-  398 (82.03/30.17)	..VDSAHqSPLHPST..PpaTAKR.......LESpR...Q..DRVSSP.H..KPVEQLPSTDC...HQvlPRtsqqhiprsslVDS....QTPRTGFSPE....S.SKLDSD........DAAS...GSD.NLKRKKSR
  399-  480 (72.42/25.83)	LRIE.CE.GQSADGTgkP..ARVK.......KER.RltfDviTGQIKPLTLKDPAQ..VESSA...PT..E..................................qHRTETDkqdltlslPSPFQLTNWK....ELSGN
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11151 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PLTLKDPAQVESSAPTEQHRTETDKQDLTLSL
2) VTQNEQLVRGIPNLPGSANGGGSHNCKADPAPTNLLAGKPIQELKGRNDIQKAHSPKADKTPKRKRKEHRDGGQGTPGHLSKPNHELFQNSSPPPTNGIGGSPPDNLPSPLDGGLQSNNRLEPAENDKHGKIPINAVRPHTNSPGLVKHPSTSSLLKVVVLQQHSGGLDDALSHQPRSPRCSSFSPRGTRAELATRQHTTYAPKGSAPSPSQRLPGVDSAHQSPLHPSTPPATAKRLESPRQDRVSSPHKPVEQLPSTDCHQVLPRTSQQHIPRSSLVDSQTPRTGFSPESSKLDSDDAASGSDNLKRKKSRLRIECEGQSADGTGKPARVKKERRL
434
87
465
423










Molecular Recognition Features






MoRF SequenceStartStop




1) LRIEC
399
403