<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11146

Description Uncharacterized protein
SequenceMTAAPLTPREIRERLLQAIDKHSNIHNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTSNEDLAKRAKKLLRNWQKLIEPGTQNEQFVRGIPNLPGSANGGGSHNCKADLAPTTLLCGKPIQELKSRNDIQRAHSPKAEKTTNRKRKGELRDGGQGTPGHLPKPNHELFQNSSPPPTNGVGGSPPENLPSLLDGGLQSNRLEPAENDKHGKIPVNAVRPHTNSPGLVKQPSTSSLLKAVVLQQHSGGLDDALSLQPRSPRCSSFSPRGTRAELTTRQHTTYAPKGSAPSPSQRLPGVDSAHQSPLHPSTPPATAKRLESPRQDRVSSPHKLVEQIPSTDCHQVLPRTSQQHIPRSSLLDSSPRTGFLTESSKVDSDDAASGSDNRKRKKSRFRIECEGHSADGTGKPARVRKERKLTFDVMTGQIKPLTLKDPAQVESSAPSEQHRTETDKQDLKLSLPSPFQLTNWKELSGSDIIQSYLHRQGSLLSSSGVQTQSAHYYMSEYLKQEECTKREARKTHVLVPIVLPSDLPGRTREITSSDTDRIHNQHWPGVNGCHDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length596
PositionUnknown
OrganismXenopus laevis (African clawed frog)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Amphibia> Batrachia> Anura> Pipoidea> Pipidae> Xenopodinae> Xenopus> Xenopus.
Aromaticity0.03
Grand average of hydropathy-0.866
Instability index58.68
Isoelectric point9.35
Molecular weight65734.98
Publications
PubMed=27762356

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11146
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.90|      15|      15|     339|     353|       1
---------------------------------------------------------------------------
  339-  353 (28.68/16.35)	EQIPSTDCHQVLPRT
  356-  370 (25.22/13.48)	QHIPRSSLLDSSPRT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     276.58|      86|      91|      94|     183|       2
---------------------------------------------------------------------------
   42-  135 (99.13/47.46)	......PITKEALEETRLGKL.iNDVRKKTS.NEdLAKRAKKL..........LRNWQkliEPGTqneqfVRGIP..NLPGSANGGGSHNcKadLAPT.TLLCGK.PIQELKSRND
  136-  228 (132.97/59.03)	IQrAHSPKAEKTTNRKRKGEL..RDGGQGTP.GH.LPKPNHEL..........FQNSS...PPPT...ngVGGSPpeNLPSLLDGGLQSN.R..LEPAeNDKHGKiPVNAVRPHTN
  260-  319 (44.47/13.91)	LQ.PRSPRCSSFSPRGTRAELttRQHTTYAPkGS.APSPSQRLpgvdsahqspLHPST...PPAT...................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.93|      17|      23|     391|     413|       3
---------------------------------------------------------------------------
  391-  413 (25.41/32.66)	RKRKKSRFRIECeghsadGTGKP
  417-  433 (30.52/20.76)	RKERKLTFDVMT......GQIKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.65|      14|      15|     435|     448|       4
---------------------------------------------------------------------------
  435-  448 (23.50/13.05)	TLKDPAQVESSAPS
  453-  466 (23.15/12.75)	TETDKQDLKLSLPS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11146 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) CGKPIQELKSRNDIQRAHSPKAEKTTNRKRKGELRDGGQGTPGHLPKPNHELFQNSSPPPTNGVGGSPPENLPSLLDGGLQSNRLEPAENDKHGKIPVNAVRPHTNSPGLVKQPSTSSLLKAVVLQQHSGGLDDALSLQPRSPRCSSFSPRGTRAELTTRQHTTYAPKGSAPSPSQRLPGVDSAHQSPLHPSTPPATAKRLESPRQDRVSSPHKLVEQIPSTDCHQVLPRTSQQHIPRSSLLDSSPRTGFLTESSKVDSDDAASGSDNRKRKKSRFRIECEGHSADGTGKPARVRKERKLT
2) GTQNEQFVRGIPNLPGSANGGGSHNCKADLAP
3) PLTLKDPAQVESSAPSEQHRTETDKQDLKLSL
123
87
433
423
118
464










Molecular Recognition Features






MoRF SequenceStartStop




1) FRIEC
398
402