<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11093

Description Probable cyclin-dependent kinase E-1
SequenceMSLTSNPPSSGGAGPSSANAQRTQTLKRSVQQAFDDPADRGLGPNVGYQSKVRVIDRYKVIGFISSGTYGRVYKACGRHGQTGEFAIKKFKPDKEGEQIQYTGISQSAVREMALCSELSHPSVIKLIEIILEDKCIFMVFEYAEHDLLQIIHHHTQPTRHPIPPSTVKSIMFQLLNGCQYLHANWVLHRDLKPANIMVTSSGEVKIGDLGLARLFNKPLHSLFSGDKVVVTIWYRAPELLLGSRHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVEIMGLPTKEKWPHLVNMPEYSQLSTLSTSSHPKSGSNLEKWYYSTINSHSATSNPSSNASLGAEGYKLLSGLLEYDPERRLTAQQALQHPFFSTGDKVSSNCFEGVKMEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSRPVKRLKE
Length440
PositionKinase
OrganismPhialocephala subalpina
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Helotiales> Mollisiaceae> Phialocephala> Phialocephala fortinii species complex.
Aromaticity0.08
Grand average of hydropathy-0.450
Instability index40.40
Isoelectric point9.14
Molecular weight49159.52
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11093
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.21|      15|      33|     358|     373|       1
---------------------------------------------------------------------------
  358-  373 (24.68/16.62)	GYKLLS....GL.LEYdPERR
  388-  407 (20.53/ 9.02)	GDKVSSncfeGVkMEY.PHRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.57|      10|      27|       6|      15|       3
---------------------------------------------------------------------------
    6-   15 (20.59/ 9.42)	NPPSSGGAGP
   35-   44 (19.98/ 8.97)	DDPADRGLGP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11093 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FEGVKMEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSRPVKRLKE
2) MSLTSNPPSSGGAGPSSANAQRTQTLKRSVQQAFDD
396
1
440
36










Molecular Recognition Features






MoRF SequenceStartStop




NANANA