<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11067

Description CIC11C00000000232
SequenceMSADYWSSSQRLKWQLTREGLSECRQKLILLEKKMIQSGLIKDFPQITYDVNMRIYLHTLLVKLGRRLNVRQVALATSEVYLTRFLTRVSLKEINVYLLVTTCLYVSCKIEECPQHIRLIISEARNLWPEYIPHDVTKLAEFEFYLIEEMDMYLFLHHPYKSLIQLRDFLRERQLHFGFVLSDDELQHSWSLINDSYITDLHLLFPPHVIALAAVYITIVLKKNLNSIRSGTGLIPERQGLQGDSSSMHIDDLMTISNGGRADTTMDLHNLQNNFLDPRLDEDTVKIDCFMDFFNYSHVNLDEVVEAMQEMINLYVAWDRYNENLVRKALQYMLLSR
Length337
PositionKinase
Organism[Candida] intermedia
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.10
Grand average of hydropathy-0.121
Instability index45.62
Isoelectric point5.85
Molecular weight39661.41
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP11067
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     103.31|      23|      23|     290|     312|       1
---------------------------------------------------------------------------
  266-  287 (29.70/18.19)	.MDLHNLQNNFLDPRLDEDTVKI
  290-  312 (40.68/27.41)	FMDFFNYSHVNLDEVVEAMQEMI
  315-  334 (32.92/20.89)	YVAWDRYNE.NL..VRKALQYML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.16|      16|      23|      55|      77|       4
---------------------------------------------------------------------------
   55-   70 (26.41/29.29)	IYLHTLLVKLG.RRLNV
   80-   96 (21.75/ 7.31)	VYLTRFLTRVSlKEINV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.57|      22|      27|     156|     177|       5
---------------------------------------------------------------------------
  156-  177 (38.82/25.41)	LHHPYKSLIQLRDFLRERQLHF
  186-  205 (34.16/21.56)	LQHSW.SLIN.DSYITDLHLLF
  221-  239 (23.59/12.82)	LKKNLNSIRSGTGLIPERQ...
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP11067 with CycC domain of Kingdom Fungi

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