<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11051

Description CIC11C00000003994
SequenceMSKVEPIRSAATIISSENVNVTSILSQAHKKVLVDHDVTNDEAVILALGYKAEFKREFSLLTTFGVSFSVLGLLPSIASTLWYSIAYAGNAGITWAYLVGMIGVLGVACSMAEISSAFPTSGGLYYATAMLSPPKYKAILSWWVGWSNYFTQVTGAPSVAYGCASMILALKIMVDENYVYHTWHCYLLTTGLTFASAIVASAPTKWLAWINSTSTALNLIFLFVSFVVFMGGNNRTEQGLPKFNDNNTAWAITNFTEWNDGVAILMTFMAVIWTMSGFDSPFHLAEECSNAQVATPRAIVLTAVVGGVLGFVFQLGMAYTIVDINEAVNDELGQPYVAYLNQILTRDRVIALTSLAIVLAFSMSFACMIAASRVLFSYSRDGCFPMSKYWSKVNDVTKTPVNAVWANWILGELLLLLMFGGVAIDAIFSVGAIGSFVSFTVPTLLRITYARNTFKPGPWNLGRFSYISGILAVSFVLLMIPILCFPQYKGKDNTPDMMNWTVLVYWGSMFLTVAWYYIYAHKIYLGPKSNIDAYNLVDESEDVAVIDGVISAHDVLLVHNATPGTILQFHDELSNKLPTLKGKWNFSFKIFRNNTYSIPPELASTQTTSTENKYLYTWVPSYLNDSCVTLIDKKTSAVFSHVVQEEVTNPFEFAIPNDHLHNGATSGLNDSFDYLVNQRLQSLWTQRQVIKGDGGQIYELENGNLIIRTANVTLHGNFRGLLIQLEIDHSKLDSVDVEQIFKDVTSRYDIPAGNLCHRVMDGNAFDEFGDLALQYAEILNF
Length781
PositionHead
Organism[Candida] intermedia
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.13
Grand average of hydropathy0.291
Instability index28.19
Isoelectric point5.35
Molecular weight86500.36
Publications

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
transmembrane transporter activity	GO:0022857	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP11051
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.46|      22|     100|     383|     415|       1
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  383-  415 (29.13/45.83)	CFPmsKYWSKvndvTKTP......VNAVWanwilGELLL
  484-  511 (40.33/24.67)	CFP..QYKGK....DNTPdmmnwtVLVYW.....GSMFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     384.37|     123|     209|      40|     173|       2
---------------------------------------------------------------------------
   40-  173 (200.17/144.16)	NDEAVILALGYKAEFKREFSLLTTF.GVSFSVLGL.LP.SIASTLWYSIAYAGNAGITWAYLVGMIGV...LGVACSMAEISSAFPTS.GGLY..YATAMLSPPKYKAILSWwvgwsnyftQVTGAPSVAYGCasMILALKIM
  244-  375 (184.20/110.30)	NDNNTAWAITNFTEWNDGVAILMTFmAVIWTMSGFdSPfHLAEECSNAQVATPRAIVLTAVVGGVLGFvfqLGMAYTIVDINEAVNDElGQPYvaYLNQILTRDRVIALTSL.........AIVLAFSMSFAC..MIAASRVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.19|      19|     433|     175|     194|       4
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  175-  194 (34.01/27.13)	DENYVYhTW.HCYLLTTGLTF
  611-  630 (33.18/20.58)	ENKYLY.TWvPSYLNDSCVTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.43|      23|     521|      16|      39|       5
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   16-   39 (34.05/27.72)	SENVNVTSILSQAHKKVLVdHDVT
  540-  562 (38.38/25.95)	SEDVAVIDGVISAHDVLLV.HNAT
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP11051 with Med20 domain of Kingdom Fungi

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